Version 2.77

Term Description

This is an screening assay of esophageal cancer by the retrieval of samples obtained using a non-endoscopic swallowable balloon from the distal esophageal mucosa. The test is positive if either VIM and CCNA1 DNA methylation biomarkers are present.
Source: Regenstrief LOINC

Part Description

LP150045-5   Sequencing
Sequencing is a method used to determine the sequence of individual genes, larger genetic regions (i.e. clusters of genes or operons), full chromosomes or entire genomes. Historically, most sequencing has been performed using the chain termination method developed by Frederick Sanger in 1977. PMID: 271968 Sequencing technologies have improved dramatically, making them cheaper, faster, and more accurate. Next-generation sequencing (NGS), also known as high-throughput sequencing, deep sequencing, and second-generation sequencing, is a type of technology that uses parallel sequencing of multiple small fragments of DNA to determine sequence. This "high-throughput" technology has increased the speed and amount of DNA sequenced at a significantly reduced cost. PMID: 18576944 Several NGS platforms (ie, sequencing instruments and associated reagents) have been developed. Third-generation sequencing is another methodology currently under development that uses parallel sequencing similar to NGS. In contrast to NGS, third-generation sequencing uses single DNA molecules rather than amplified DNA as a template. PMID: 20858600 Source: Regenstrief LOINC

Fully-Specified Name

Component
Noninvasive esophageal cancer DNA+esophageal cell screening
Property
PrThr
Time
Pt
System
Esophagus
Scale
Ord
Method
Sequencing

Additional Names

Short Name
Noninv esophageal Ca screen Esoph Ql Seq
Display Name
Noninvasive esophageal cancer DNA and esophageal cell screening Sequencing Ql (Esophagus)
Consumer Name Alpha Get Info
Noninvasive esophageal cancer DNA and esophageal cell screening, Esophagus

Example Answer List: LL2021-5

Source: Gen-Probe
Answer Code Score Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6
InvalidCopyright http://snomed.info/sct ID:455371000124106 Invalid result (qualifier value) LA15841-2

Basic Attributes

Class
MOLPATH
Type
Laboratory
First Released
Version 2.75
Last Updated
Version 2.75
Order vs. Observation
Both

Language Variants Get Info

Tag Language Translation
it-IT Italian (Italy) DNA del cancro esofageo + cellule esofagee, screening non invasivo:PrThr:Pt:Esofago:Ord:Sequenziamento
Synonyms: Patologia molecolare Presenza o Soglia Punto nel tempo (episodio) Screening non invasivo del DNA del cancro esofageo e cellule esofagee
zh-CN Chinese (China) 无创性食管癌 DNA+食管细胞筛查:存在情况或阈值:时间点:食管:序数型:序列测定
Synonyms: Asympt SCN 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 分子病理学;分子病理学试验 去氧核糖核酸;脱氧核糖核酸;脱氧核糖核酸（Deoxyribonucleic acid，DNA） 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 序列分析;测序 无创性（非侵入式、非侵入性、非创伤性）食管癌 DNA+食管细胞筛查 无症状 无症状（Asymptomatic，Asympt） 无症状的 无症状筛查 时刻;随机;随意;瞬间 普查 普查试验 癌 筛分 筛分试验 筛查（Screening，SCN） 筛查试验 筛选 筛选试验 食道

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=101906-6