102082-5
Alpha-1-Antitrypsin Proteotype Panel - Serum or Plasma
Active
6771-0 Alpha 1 antitrypsin [Mass/volume] in Serum or Plasma by Nephelometry
Part Descriptions
LP14643-8 Alpha 1 antitrypsin
Used to diagnose hereditary hypo α1-antitrypsin (α1AT). An increased prevalence of non-MM phenotypes is found with cryptogenic cirrhosis and with CAH. Cirrhosis in a child should raise consideration of α1AT deficiency or Wilson's disease. Diagnosis of inflammatory states, if elevated (eg, rheumatoid arthritis, bacterial infection, vasculitis, neoplasia). Alpha 1-antitrypsin or α1-antitrypsin (A1AT) is a serine protease inhibitor (serpin). It protects tissue from enzymes from inflammatory cells, especially elastase, and is present in human blood at 1.5 - 3.5 gram liter.
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Source: Wikipedia, Alpha 1 antitrypsin (Wikipedia)
Fully-Specified Name
- Component
- Alpha 1 antitrypsin
- Property
- MCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
- Nephelometry
Additional Names
- Short Name
- A1AT SerPl Neph-mCnc
- Display Name
- Alpha 1 antitrypsin Nephelometry [Mass/Vol]
- Consumer Name Alpha Get Info
- Alpha 1 antitrypsin, Blood
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 1.0h(2)
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 1494
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 102082-5 | Alpha-1-Antitrypsin Proteotype Panel - Serum or Plasma |
| 102088-2 | Torch Ab.IgG panel - Serum |
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG6779-5 | Alpha 1 antitrypsin| |
| LG42372-9 | Alpha 1 antitrypsin| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-DE | German (Germany) | Alpha-1-Antitrypsin: |
| es-MX | Spanish (Mexico) | Antitripsina alfa 1: |
| es-ES | Spanish (Spain) | Alfa 1 antitripsina: Synonyms: Cuantitativo |
| es-AR | Spanish (Argentina) | dispersión de la luz: |
| et-EE | Estonian (Estonia) | Alfa-1-antitrüpsiin: Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma |
| fr-CA | French (Canada) | Alpha 1 antitrypsine: |
| fr-BE | French (Belgium) | Alpha 1 antitrypsine: Synonyms: AAT |
| fr-FR | French (France) | Alpha-1-antitrypsine: |
| it-IT | Italian (Italy) | Alfa 1 antitripsina: Synonyms: Chimica Concentrazione di Massa Nefelometria Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
| ko-KR | Korean (Korea, Republic Of) | 알파 1-항트립신: |
| nl-NL | Dutch (Netherlands) | alfa-1-antitrypsine: Synonyms: nefelometrische methode |
| pt-BR | Portuguese (Brazil) | Alfa 1 antitripsina: Synonyms: ; |
| ru-RU | Russian (Russian Federation) | Альфа 1 антитрипсин: Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени; |
| tr-TR | Turkish (Turkey) | Alfa 1 antitripsin: |
| uk-UA | Ukrainian (Ukraine) | Альфа-1-антитрипсин: Synonyms: A1; |
| zh-CN | Chinese (China) | Alpha 1 抗胰蛋白酶: Synonyms: Ⅰ A1 型 A1A; |
Example Units
| Unit | Source |
|---|---|
| g/L | Example UCUM Units |
| g/L | eCHN |
49244-7 Alpha 1 antitrypsin phenotype [Interpretation] in Serum or Plasma Narrative
Part Descriptions
LP17187-3 Alpha 1 antitrypsin phenotype
Alpha-1 antitrypsin deficiency is a relatively common autosomal recessive condition. The most common deficiency alleles in the alpha-1-antitrypsin gene on the protease inhibitor locus are PI*Z and PI*S. The normal allele is PI*M. Patients homozygous for PI*Z or PI*S or heterozygous PI*Z/PI*S will have decreased alpha-1-antitrypsin levels, with PI*Z/PI*Z having lowest levels of 10-20% of normal. Patients with PI*Z/PI*Z or PI*S/PI*Z genotypes reportedly have increased risk of childhood liver disease and chronic obstructive pulmonary disease(COPD) and emphysema in adult life. PI*M/PI*Z patients may have decreased pulmonary function and increased risk for COPD, especially smokers.
Source: Regenstrief Institute
Fully-Specified Name
- Component
- Alpha 1 antitrypsin phenotype
- Property
- Imp
- Time
- Pt
- System
- Ser/Plas
- Scale
- Nar
- Method
Additional Names
- Short Name
- A1AT Phenotyp SerPl-Imp
- Display Name
- Alpha 1 antitrypsin phenotype Nar [Interp]
- Consumer Name Alpha Get Info
- Interpretation of Alpha 1 antitrypsin phenotype test result, Blood
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.21
- Last Updated
- Version 2.73
- Change Reason
- Release 2.71: COMPONENT: Changed for naming consistency across LOINC.;
- Order vs. Observation
- Observation
- Common Test Rank Get Info
- 6812
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 102082-5 | Alpha-1-Antitrypsin Proteotype Panel - Serum or Plasma |
| 102088-2 | Torch Ab.IgG panel - Serum |
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG13381-5 | Alpha 1 antitrypsin phenotype| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | Fenotipo Alfa 1 antitripsina: |
| es-MX | Spanish (Mexico) | Fenotipado de alfa 1 antitripsina: |
| fr-BE | French (Belgium) | Phénotypage de l'alpha-1-antitrypsine: Synonyms: AAT |
| fr-CA | French (Canada) | Phénotype de l'alpha 1 antitrypsine: |
| fr-FR | French (France) | Alpha-1-antitrypsine phénotype: |
| it-IT | Italian (Italy) | Alfa 1 antitripsina, fenotipo: Synonyms: Chimica Fenotipo dell''alfa 1 antitripsina Impressione/interpretazione di studio Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
| nl-NL | Dutch (Netherlands) | alfa-1-antitrypsine fenotype: |
| pt-BR | Portuguese (Brazil) | Alfa 1 antitripsina Fenotipagem: Synonyms: ; |
| ru-RU | Russian (Russian Federation) | Альфа 1 антитрипсин фенотипирование: Synonyms: Впечатление/интерпретация исследования Описательный Плазма Сыворотка Сыворотка или Плазма Точка во времени; |
| tr-TR | Turkish (Turkey) | Alfa 1 antitripsin fenotipleme: |
| uk-UA | Ukrainian (Ukraine) | Альфа-1-антитрипсин фенотип: Synonyms: A1; |
| zh-CN | Chinese (China) | Alpha 1 抗胰蛋白酶表现型: Synonyms: Ⅰ A1 型 A1A; |