Version 2.80

Part Description

LP204843-9   Rotavirus A
Rotaviruses are non-enveloped, multilayered, icosahedral viruses composed of an outer layer, an inner layer, and a core. After the immature, double-layered virus is assembled in the host cell cytoplasm, they bud across the endoplasmic reticulum (ER) and acquire a temporary membrane that has on its surface the ER resident viral glycoproteins NSP4, VP4 and VP7. The virus loses its temporary membrane and the NSP4 glycoprotein as it moves toward the center of the ER cisternae. The VP4 and VP7 proteins are pushed to the outermost membrane layer and become the mature triple-layered rotavirus. The outer capsid glycoprotein VP7 is believed to be important for the attachment to and entry in the host cell. After it enters the host cell, the VP7 glycoprotein is lost. [UniProt: Q89865] When the host cell lyses, the mature virus are released. There are eight groups of rotavirus, A through H. Groups A, B, C, and H are associated with an acute gastroenteritis and are found in humans and animals. Groups D, E, F, and G are found only in animals. Rotavirus A (RVA) are the cause an acute gastroenteritis in children and animals. RVA is the most common infectious organism to cause severe gastroenteritis in children less than 3 years of age. It is estimated that 95% of children worldwide between the ages of 3 and 5 will become infected with RVA. Approximately 8000 children under 5 years of age in Latin America and the Caribbean die of acute enteritis caused by RVA. PMID: 2556635[http://www.sciencedirect.com/science/article/pii/S004268220700400X?via%3Dihub] PMID: 27462899 Source: Regenstrief LOINC

Fully-Specified Name

Component
Rotavirus A RNA
Property
PrThr
Time
Pt
System
XXX
Scale
Ord
Method

Additional Names

Long Common Name
Rotavirus A RNA [Presence] in Specimen
Short Name
RVA RNA Spec Ql
Display Name
Rotavirus A RNA Ql (Specimen)
Consumer Name Alpha Get Info
Rotavirus A, Specimen

Example Answer List: LL744-4

Source: Regenstrief Institute
Answer Code Score Answer ID
Detected LA11882-0
Not detected LA11883-8

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.78
Last Updated
Version 2.78 (ADD)
Order vs. Observation
Both

Language Variants Get Info

Tag Language Translation
el-GR Greek (Greece) Ροταϊός Α RNA:PrThr:Pt:XXX:Ord:
Synonyms: PrThr
es-ES Spanish (Spain) Rotavirus A RNA:PrThr:Punto temporal:XXX:Ord:
fr-FR French (France) Rotavirus A ARN:Présence/Seuil:Ponctuel:Milieux divers:Qualitatif:
it-IT Italian (Italy) Rotavirus A RNA:PrThr:Pt:XXX:Ord:
Synonyms: Microbiologia Presenza o Soglia Punto nel tempo (episodio)
nl-NL Dutch (Netherlands) Rotavirus A RNA:aanwezigheid:moment:XXX:ordinaal:
pl-PL Polish (Poland) Rotawirus grupy A RNA:granica wykrywalności:punkt w czasie:XXX:półilościowy:
Synonyms: RNA Rotawirusa A
zh-CN Chinese (China) 轮状病毒 A 组 RNA:存在情况或阈值:时间点:XXX:序数型:
Synonyms: A 型 ROTAV;RV 不明的;其他;将在相应消息内其他部分之中加以详细说明;未作详细说明的;未作说明的;未做说明的标本;未加规定的;未加说明的标本;杂项 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 时刻;随机;随意;瞬间 核糖核酸;Ribonucleic acid 轮状病毒（ROTAV、RV） A 组;A 组轮状病毒

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=105056-6