Version 2.78

Term Description

APC Resistance is a ratio of aPTT with APC to aPTT without APC
Source: Regenstrief LOINC

Part Descriptions

LP18494-2   Activated protein C resistance
A hemostatic disorder characterized by a poor anticoagulant response to activated protein C (APC) which increases the risk of a clotting disorder. The activated form of Factor V (Factor Va) is more slowly degraded by activated protein C. Factor V Leiden mutation (R506Q) is the most common cause of APC resistance. Source: National Library of Medicine, MeSH 2006

LP18494-2   Activated protein C resistance
Activated protein C resistance (APC) has emerged as the most frequent abnormality in patients with idiopathic thrombosis. Patients found to be heterozygous for APC resistence have a seven fold increased risk for venous thrombosis as compared to the general popualtion. Homozygous individuals have an eight fold increased risk of thrombosis. Familial studies and counselling should be considered for positive patients. The activated form of Factor V (Factor Va) is more slowly degraded by activated protein C. Factor V Leiden mutation (R506Q) is the most common cause of APC resistance. Often measured as the ratio of the Appt W APC. Source: Regenstrief Institute

Fully-Specified Name

Component
Activated protein C resistance
Property
TRto
Time
Pt
System
PPP
Scale
Qn
Method
Coag

Additional Names

Short Name
aPCR PPP
Display Name
Activated protein C resistance Coag (PPP) [Time ratio]
Consumer Name Alpha Get Info
Activated Protein C Resistance, Blood

Basic Attributes

Class
COAG
Type
Laboratory
First Released
Version 1.0k
Last Updated
Version 2.73
Order vs. Observation
Both
Common Test Rank Get Info
2793

Member of these Panels

LOINC Long Common Name
48596-1 Activated protein C resistance panel - Platelet poor plasma

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Aktiviertes-Protein-C-Resistenz:Zeitverhältnis:Zeitpunkt:Thrombozytenarmes Plasma:Quantitativ:Gerinnungstest
Synonyms: APC-Resistenz
de-AT German (Austria) Synonyms: APC-Resistenz (Ratio)
es-MX Spanish (Mexico) Resistencia a la proteína C activada:Razón de tiempo:Punto temporal:Plasma pobre en plaquetas:Cuantitativo:Ensayo de coagulación
es-ES Spanish (Spain) Resistencia a la proteína C activada:Relacion de Tiempo:Punto temporal:Plasma pobre en plaquetas:Qn:Coagulativo
Synonyms: Cuantitativo
es-AR Spanish (Argentina) resistencia a la proteína C activada:relación de tiempo:punto en el tiempo:plasma desplaquetado:cuantitativo:coagulación
et-EE Estonian (Estonia) Aktiveeritud proteiini C resistentsus:TRto:Pt:PPP:Qn:Koagulomeetria
Synonyms: Juhuslik Kvantitatiivne Trombotsüütidevaene plasma
fr-CA French (Canada) Résistance à la protéine C activée:Ratio de temps:Temps ponctuel:Plasma pauvre en plaquettes:Quantitatif:Test de coagulation
fr-FR French (France) Protéine C activée résistance:Temps (Ratio):Ponctuel:Plasma pauvre en plaquettes:Numérique:Coagulation
fr-BE French (Belgium) Résistance à la protéine C activée:Ratio de temps:Temps ponctuel:Plasma pauvre en plaquettes:Quantitatif:Test de coagulation
Synonyms: Rapport. Temps RPCa Test d''Hémostase
it-IT Italian (Italy) Proteina C attivata, resistenza:TRto:Pt:PPP:Qn:Coag
Synonyms: Plasma povero di piastrine Punto nel tempo (episodio) Rapporto Tempo Resistenza alla proteina C attivata Studio di coagulazione Test di coagulazione
ko-KR Korean (Korea, Republic Of) 활성 C 단백 내성:시간율:검사시점:혈소판제거혈장:정량:응고검사
nl-NL Dutch (Netherlands) geactiveerd proteïne C-resistentie:tijdsverhouding:moment:plaatjesarm plasma:kwantitatief:stollingsmethode
Synonyms: coagulatiemethode
pt-BR Portuguese (Brazil) Resistência a Proteína C ativada:TRto:Pt:PPPQ:Qn:Coagulação
Synonyms: ; Prot C; PC; Autoprothrombin II-a; PR; aPCR; APCr; APC-R; Time ratio; Point in time; Random; Platelet poor plasma; Plas; Quantitative; QNT; Quant; Quan; Coagulation assay; Clot; Tilt tube; ClottAcle; Resistanc; Resist; Resistent; Resistant; APC
ru-RU Russian (Russian Federation) Активированный протеин С резистентность:Время доля:ТчкВрм:ОПП:Колич:Коаг
Synonyms: Анализ факторов свертывания крови;Коагулограмма Белок Белок C Доля в общем времени;Временное отношение Количественный Обеднённая пластинками плазма;Бедная тромбоцитами плазма Точка во времени;Момент
tr-TR Turkish (Turkey) Aktiflenmiş protein C resistans:ZOran:Zmlı:TFkP:Kant:Koag
uk-UA Ukrainian (Ukraine) Резистентність до активованого протеїну С:Часове Співвідношення:МоментЧасу:Бідна тромбоцитами плазма:Кількісно:Аналіз коагулограми
Synonyms: Activ; APC; APCr; APC-R; Autoprothrombin II-a; Clot; Clottable; COAGULATION; Coagulation assay; Hematology; Heme; PC; Plas; Platelet poor plasma; Point in time; PR; Prot; Prot C; QNT; Quan; Quant; Quantitative; Random; Resist; Resistanc; Resistant; Resistent; Tilt tube; Time ratio; UniversalLabOrders
zh-CN Chinese (China) 活化蛋白 C 抗性:时间比率:时间点:贫血小板血浆:定量型:凝血功能分析
Synonyms: APC 抗性;APC 抵抗;aPCR;APC-R;活化 C 蛋白抗性;活化蛋白 C 抗性（Activated protein C resistance，APC-R）;活化蛋白 C 抗性是采用 APC 的 aPTT 与不采用 APC 的 aPTT 之比。;活化蛋白 C 抵抗;活化蛋白 C 抵抗性 C 型;丙;丙型 C 蛋白;PC;自体凝血因子 II-a;自体凝血素 II-a;自体凝血酶原 II-a;自体前凝血酶 II-a;自体因子 II-a;自体第二凝血因子-a;自体第二因子-a;自身凝血因子 II-a;自身凝血素 II-a;自身凝血酶原 II-a;自身前凝血酶 II-a;自身因子 II-a;自身第二凝血因子-a;自身第二因子-a;蛋白 C（Protein C，PC）;蛋白质 C PR;Prot;成分 - 化学 - 蛋白质类;蛋白;朊;蛋白质类;蛋白质类物质 乏血小板血浆;Platelet poor plasma;PPP 倾斜试管;倾斜试管法;凝固测定;凝血功能测定;凝血测定;快速凝固试验;快速凝血试验;快速凝集试验 凝血功能;凝血功能试验;凝血过程;血液凝固;血液凝固功能;血液凝固过程 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 抗力 抗耐性 抵抗力 抵抗性 时刻;随机;随意;瞬间 时间比 活化型蛋白C（Activated protein C，APC） 激活型蛋白C 激活型蛋白C（Activated protein C，APC） 电阻 耐性 阻力

Example Units

Unit Source
{ratio} Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=13590-5