13955-0

Hepatitis C virus Ab [Presence] in Serum or Plasma by Immunoassay

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Part Description

LP14400-3 Hepatitis C virus
Hepatitis C virus (HCV) is a small (50 nm in size), enveloped, single-stranded, positive sense RNA virus in the genus hepacivirus, which is in the Flaviviridae family. More than 170 million people worldwide are affected by hepatitis C, and the majority of patients with acute hepatitis C develop chronic HCV infection, which can result in liver cirrhosis, hepatic failure or hepatocellular carcinoma. The HCV core protein is a highly basic, RNA-binding protein that forms the viral capsid. The E1 and E2 envelope glycoproteins are necessary for viral entry and fusion. Non-structural proteins include NS2, NS3, NS4A and 4B, and NS5A and 5B. The NS2-NS3 complex functions as a protease, and NS3 also has a helicase/NTPase domain. NS4A is a cofactor of NS3 protease activity. NS3-NS4A protease is one target of anti-HCV drugs. NS4B is a membrane anchor for the replication complex, and NS5A plays a role in regulating viral replication. NS5B is an RNA-dependent RNA polymerase. [NCBI Books: NBK1630] Source: Regenstrief LOINC, NCBI Books: NBK1630

Fully-Specified Name

Component: Hepatitis C virus Ab
Property: PrThr
Time: Pt
System: Ser/Plas
Scale: Ord
Method: IA

Additional Names

Short Name: HCV Ab SerPl Ql IA
Display Name: HCV Ab IA Ql
Consumer Name Alpha Get Info: Hepatitis C virus (HCV) antibody, Blood

Example Answer List: LL360-9

Source: Regenstrief Institute

Answer	Code	Score	Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value)			LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value)			LA6577-6

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 1.0k
Last Updated: Version 2.73
Change Reason: The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation: Both
Common Test Rank Get Info: 393

Member of these Panels

LOINC	Long Common Name
24363-4	Acute hepatitis 2000 panel - Serum
75886-2	HCV antibody screening - Meaningful Use set
106060-7	Hepatitis B and C virus Ab panel - Serum by NAA with probe detection
72061-5	Vaccination panel [ESRD]

Member of these Groups Get Info

LOINC Group	Group Name
LG32754-0	Hepatitis C virus

Language Variants Get Info

Tag	Language	Translation
de-DE	German (Germany)	Hepatitis-C-Virus Ak:Nachweis oder Schwellenwert:Zeitpunkt:Serum oder Plasma:Ordinal:Immunoassay Synonyms: Hepacivirus C; HCV
el-GR	Greek (Greece)	Ιός Ηπατίτιδας C Αντίσωμα:PrThr:Χρονική στιγμή:Ορός/Πλάσμα:Τακτική:IA Synonyms: Ab
es-MX	Spanish (Mexico)	Virus de la hepatitis C Ab:Presencia o umbral:Punto temporal:Suero o Plasma:Ordinal:Inmunoensayo
es-ES	Spanish (Spain)	Virus Hepatitis C Anticuerpos:PrThr:Punto temporal:Suero o Plasma:Ord:IA
es-AR	Spanish (Argentina)	[anticuerpo anti - ] virus de hepatitis C [Ac]:concentración arbitraria:punto en el tiempo:suero:ordinal:enzimoinmunoanálisis
et-EE	Estonian (Estonia)	C-hepatiidi viirus antikehad:PrThr:Pt:S/P:Ord:IA Synonyms: Järgarvuline Juhuslik Plasma Seerum Seerum või plasma
fr-CA	French (Canada)	Virus de l'hépatite C, Ac:Présence-Seuil:Temps ponctuel:Sérum/Plasma:Ordinal:IA
fr-FR	French (France)	Hépatite C virus Ac:Présence/Seuil:Ponctuel:Sérum/Plasma:Qualitatif:Immunoanalyse
fr-BE	French (Belgium)	Virus de l'hépatite C Ac:PrThr:Temps ponctuel:Sérum/Plasma:Ordinal:IA Synonyms: Anticorps HCV
it-IT	Italian (Italy)	Epatite C, virus Ab:PrThr:Pt:Siero/Plasma:Ord:IA Synonyms: anticorpo Immunoassay Microbiologia Plasma Presenza o Soglia Punto nel tempo (episodio) Siero Siero o Plasma Virus dell''epatite C
ko-KR	Korean (Korea, Republic Of)	C형 간염 바이러스 항체:임의농도:검사시점:혈청:순위척도:효소면역측정법
nl-NL	Dutch (Netherlands)	Hepatitis C-virus As:aanwezigheid:moment:serum of plasma:ordinaal:immunoassay Synonyms: antistof; antilichaam IA
pl-PL	Polish (Poland)	Wirus zapalenia wątroby typu C Ab:granica wykrywalności:punkt w czasie:surowica lub osocze:półilościowy:metoda immunologiczna Synonyms: Przeciwciała do wirusa zapalenia wątroby typu C
pt-BR	Portuguese (Brazil)	Hepatite C vírus Ac:ACnc:Pt:Soro:Ord:Imunoensaio Synonyms: HCVAc; Hep C; HCV; Arbitrary concentration; Point in time; Random; Serum; SR; Ql; Ordinal; QL; Qualitative; Qual; Screen; Enzyme immunoassay; ELISA; MEIA; SUDS; ELFA; IAA; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; Hepatit; Hepatis; Microbiology
ru-RU	Russian (Russian Federation)	Гепатита С вирус Ат:PrThr:ТчкВрм:Сыв/Плаз:Пор:IA Synonyms: Антитело Плазма Порядковый Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR	Turkish (Turkey)	Hepatit C virüsü Ab:MevcEşik:Zmlı:Ser/Plaz:Srl:İA Synonyms: Ak İmmünölçüm, immünoassay Mevcut
uk-UA	Ukrainian (Ukraine)	Вірус Гепатиту С Антитіла:Наявність або Поріг:МоментЧасу:Сироватка/Плазма:Порядково:Імуноаналіз Synonyms: ABS; Aby; Antby; Anti; Antibodies; Antibody; Autoantibodies; Autoantibody; EIA; ELFA; ELISA; Enzyme immunoassay; HCV; HCVAB; Hep; Hep C; Hepatis; Hepatit; Hepatology; IAA; ID; Infectious Disease; InfectiousDisease; Liver; MEIA; Microbiology; Ordinal; Pl; Plasma; Plsm; Point in time; PR; QL; Qual; Qualitative; Random; Screen; SerP; SerPl; SerPlas; Serum; Serum or plasma; SR; SUDS; UniversalLabOrders
zh-CN	Chinese (China)	丙型肝炎病毒抗体:存在情况或阈值:时间点:血清/血浆:序数型:免疫测定法 Synonyms: Ab;自身抗体 C 型;丙;丙型 HCV Ab HCV 抗体 HCV;Hep C;丙型肝炎;丙肝;丙肝病毒;肝炎病毒 C 型 HCVAb Hep C Ab Hep C 抗体丙型肝炎病毒 Ab 丙肝病毒 Ab 丙肝病毒抗体传染性肝炎传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）时刻;随机;随意;瞬间肝肝炎病毒 C 型 Ab 肝炎病毒 C 型抗体血清或血浆

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