17351-8
Neutrophil cytoplasmic Ab [Presence] in Serum
Active
Part Descriptions
LP16728-5 Neutrophil cytoplasmic
Neutrophil cytoplasmic antibodies are autoantibodies that bind to the granulocytes of neutrophils. These antibodies were first identified in patients with Wegener's granulomatosis (WG) who also had systemic vasculitis and necrotizing crescentic glomerulonephritis. When viewed under a fluorescent microscope, a typical cytoplasmic fluorescent pattern is visible. These ANCA are called cytoplasmic ANCA (c-ANCA) and the antigen they target is proteinase 3 (PR3) which is part of the azurophilic granules of neutrophils. The perinuclear ANCA (p-ANCA) targets the antigen myeloperoxidase (MPO) and is associated with idiopathic forms of systemic vasculitis and glomerulonephritis. A third ANCA antibody is the atypical ANCA (a-ANCA). The presence of a-ANCA has been found in patients with inflammatory bowel diseases including ulcerative colitis (UC) and Crohn's disease (CD), autoimmune-mediated liver diseases, rheumatoid arthritis RA, and systemic lupus erythematosus (SLE). PMID: 27366026
Source: Regenstrief LOINC
LP39202-4 Neutrophil cytoplasmic Ab
Anti-neutrophil cytoplasmic antibodies (ANCAs) constitute a group of auto-antibodies, mainly IgG, directed against antigens in the cytoplasm of neutrophil granulocytes (the most common type of white blood cell) and monocytes. They are detected in vitro in a number of autoimmune disorders, but are particularly associated with systemic vasculitis.
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Source: Wikipedia, Neutrophil cytoplasmic (Wikipedia)
Fully-Specified Name
- Component
- Neutrophil cytoplasmic Ab
- Property
- PrThr
- Time
- Pt
- System
- Ser
- Scale
- Ord
- Method
Additional Names
- Short Name
- ANCA Ab Ser Ql
- Display Name
- Neutrophil cytoplasmic Ab Ql (S)
- Consumer Name Alpha Get Info
- Neutrophil cytoplasmic antibody, Blood
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 1.0l
- Last Updated
- Version 2.73
- Change Reason
- The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 3632
Member of these Panels
LOINC | Long Common Name |
---|---|
87427-1 | Neutrophil cytoplasmic Ab panel - Serum by Immunofluorescence |
Member of these Groups Get Info
LOINC Group | Group Name |
---|---|
LG5096-5 | Neutrophil cytoplasmic Ab| |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
de-AT | German (Austria) | Synonyms: ANCA ql. |
es-AR | Spanish (Argentina) | anticuerpo citoplasmático antineutrófilo: |
es-ES | Spanish (Spain) | Citoplasma de neutrófilo Anticuerpos: |
es-MX | Spanish (Mexico) | Ab citoplasmático de neutrófilos: |
fr-CA | French (Canada) | Neutrophile cytoplasmique, Ac: |
fr-FR | French (France) | Cytoplasme des polynucléaires neutrophiles anticorps: |
fr-BE | French (Belgium) | Neutrophile cytoplasmique Ac: Synonyms: Anticorps |
it-IT | Italian (Italy) | Neutrofilo citoplasmico Ab: Synonyms: anticorpo Presenza o Soglia Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant |
ko-KR | Korean (Korea, Republic Of) | 호중구 세포질 항체: |
nl-NL | Dutch (Netherlands) | neutrofiel cytoplasmatisch As: Synonyms: antistof; |
pl-PL | Polish (Poland) | Cytoplazmatyczny neutrofila Ab: Synonyms: Neutrofil Przeciwciała do cytoplazmy neutrofili |
pt-BR | Portuguese (Brazil) | Citoplasma dos Neutrófilos Ac: Synonyms: ANCA; |
ru-RU | Russian (Russian Federation) | Нейтрофилов цитоплазматический Ат: Synonyms: Антитело Порядковый Сыворотка Точка во времени; |
tr-TR | Turkish (Turkey) | Nötrofil sitoplazmik Ab: Synonyms: Ak Mevcut |
zh-CN | Chinese (China) | 嗜中性粒细胞细胞浆 抗体: Synonyms: Ab; |
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