Version 2.78

Part Description

LP19835-5   t(12;21)(p13;q22.3)(ETV6,RUNX1)
The chromosomal translocation t(12;21)(p13;q22) results in a fused transcript between ETV6-RUNX1 (TEL-AML1) genes and is the most common translocation in B cell childhood acute lymphoblastic leukemia (ALL), accounting for 25% of childhood ALL. Molecular and cytogenetic techniques such as real-time PCR and FISH are used to detect the ETV6-RUNX1 fused transcripts. Source: Regenstrief LOINC

Fully-Specified Name

Component
t(12;21)(p13;q22.3)(ETV6,RUNX1) fusion transcript
Property
Arb
Time
Pt
System
Bld/Tiss
Scale
Ord
Method
Molgen

Additional Names

Short Name
t(12;21)(ETV6,RUNX1) Bld/T Ql
Display Name
t(12;21)(p13;q22.3)(ETV6,RUNX1) fusion transcript Molgen Ql (Bld/Tiss)
Consumer Name Alpha Get Info
t(12;21)(p13;q22.3)(ETV6,RUNX1) fusion transcript analysis, Blood or tissue specimen

Basic Attributes

Class
MOLPATH.TRNLOC
Type
Laboratory
First Released
Version 1.0m
Last Updated
Version 2.73
Change Reason
Changed gene name CBFA2 to RUNX1, the recommended gene name by the HUGO Gene Nomenclature Committee (HGNC). Updated Component part to harmonize with ISCN guidelines and current LOINC nomenclature.
Order vs. Observation
Observation
Common Test Rank Get Info
16808

Member of these Panels

LOINC Long Common Name
72103-5 Acute and chronic leukemia fusion transcript panel - Blood or Tissue by Molecular genetics method

Language Variants Get Info

Tag Language Translation
es-AR Spanish (Argentina) translocación del gen T(12,21)(ETV6,CBFA2):arbitrario:punto en el tiempo:sangre entera/tejido:ordinal:genética molecular
es-ES Spanish (Spain) t(12;21)(p13;q22.3)(ETV6,RUNX1) Tránscritos de fusión:Arbitrario:Punto temporal:Sangre o tejido:Ord:Genética molecular
es-MX Spanish (Mexico) t (12; 21) (p13; q22.3) (ETV6, RUNX1) transcripción de fusión:Arbitrario:Punto temporal:Sangre o tejido:Ordinal:Genética molecular
fr-FR French (France) t(12;21)(p13;q22.3)(ETV6,RUNX1) transcrit de fusion:Arbitraire:Ponctuel:Sang/Tissu:Qualitatif:Biologie moléculaire
fr-CA French (Canada) t(12;21)(p13;q22.3)(ETV6,RUNX1) transcrit de fusion:Arbitraire:Temps ponctuel:Sang/Tissu:Ordinal:Molgen
it-IT Italian (Italy) t(12;21)(p13;q22.3)(ETV6,RUNX1), trascritto di fusione:Arb:Pt:Sangue/Tess:Ord:Molgen
Synonyms: Arbitrario Genetica molecolare Patologia molecolare Punto nel tempo (episodio) Sangue Sangue o Tessuto Tessuto & Strisci Traslocazione genetica
ko-KR Korean (Korea, Republic Of) t(12,21)(ETV6,CBFA2) 유전자 전위:임의적분:검사시점:전혈/조직:순위척도:분자유전
nl-NL Dutch (Netherlands) t(12;21)(p13;q22.3)(ETV6,RUNX1) fusietranscript:aanwezigheid:moment:bloed of weefsel:ordinaal:moleculair genetisch onderzoek
Synonyms: molgen
pt-BR Portuguese (Brazil) t(12,21)(ETV6,CBFA2) translocação do gene:Arb:Pt:Sg/Tecido:Ord:Genética molecular
Synonyms: Arbitrary; Point in time; Random; Bld/T; Tissue; Bld/T; Blood; WB; Whole blood; Ql; Ordinal; QL; Qualitative; Qual; Screen; PCR; Molecular genetics; T prime; Tel oncogene; TEL; Translocation ets leukemia; TEL1; ets variant gene 6; AML1; Acute myeloid leukemia 1; MOLPATH.TRANSLOCATION; MOLPATH.TRANSLOCATION; Molecular pathology
ru-RU Russian (Russian Federation) t(12;21)(p13;q22.3)(ETV6,RUNX1) слияния транскрипт:Произв:ТчкВрм:Кр/Тк:Пор:МолГен
Synonyms: Кровь Кровь или Ткань Порядковый Произвольный Ткань и мазки Точка во времени;Момент химерная РНК, закодированная слитым геном
tr-TR Turkish (Turkey) t(12;21)(p13;q22.3)(ETV6,RUNX1) füzyon transkript:Sç:Zmlı:Kan/Dk:Srl:Molgen
zh-CN Chinese (China) t(12;21)(p13;q22.3)(ETV6,RUNX1) 融合转录物:任意型:时间点:全血/组织:序数型:分子遗传学类实验室方法
Synonyms: AML1 ETS 变体基因 6 ETS 差异基因 6 ETS 突变体基因 6 ETS 突变基因 6 ETS 突变基因 6（ets variant gene 6，ETV6） T(12,21)(ETV6,CBFA2) 基因易位;T(12,21)(ETV6,CBFA2) 易位 TEL TEL 癌基因 TEL 癌基因（Tel oncogene） TEL 致癌基因 TEL1 任意;任意的;人工型 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 全血或组织;血液/组织;血液或组织 分子病理学.基因易位;分子病理学.易位;分子病理学试验.基因易位;分子病理学试验.易位;分子病理学试验类.易位;基因易位 分子病理学;分子病理学试验 分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内，用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应 急性髓性白血病 1 急性髓系白细胞 1 急性髓系白细胞 1（Acute myeloid leukemia 1） 急性髓细胞白血病 1 时刻;随机;随意;瞬间 易位 ETS 白血病 易位 ETS 白血病（Translocation ets leukemia，TEL） 未作说明的组织;组织;组织 & 涂片 融合转录物（转录本、转录产物、转录子、转录）;融合基因转录本;融合转录 血;血液

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=21806-5