25117-3
Methylsuccinate/Creatinine [Molar ratio] in Urine
Active
Part Descriptions
LP18443-9 Methylsuccinate
Methylsuccinic acid is a normal metabolite found in human fluids. Increased urinary levels of Methylsuccinic acid (together with ethylmalonic acid) are the main biochemical measurable features in ethylmalonic encephalopathy [OMIM: 602473], a rare metabolic disorder with an autosomal recessive mode of inheritance that is clinically characterized by neuromotor delay, hyperlactic acidemia, recurrent petechiae, orthostatic acrocyanosis, and chronic diarrhea. PMID: 12382164
Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.)
Source: Human Metabolome Database, Human Metabolome Database (Methylsuccinic acid)
LP32035-5 Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas.
Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.)
Source: Human Metabolome Database, Creatinine
Fully-Specified Name
- Component
- Methylsuccinate/Creatinine
- Property
- SRto
- Time
- Pt
- System
- Urine
- Scale
- Qn
- Method
Additional Names
- Short Name
- Me-succinate/Creat Ur-sRto
- Display Name
- Methylsuccinate/Creatinine (U) [Molar ratio]
- Consumer Name Alpha Get Info
- Methylsuccinate/Creatinine, Urine
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.00
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 9073
Member of these Panels
LOINC | Long Common Name |
---|---|
48797-5 | Organic acids panel - Urine |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
de-DE | German (Germany) | Methylsuccinat/Creatinin: |
es-AR | Spanish (Argentina) | metilsuccinato/creatinina: |
es-ES | Spanish (Spain) | Metilsuccinato/Creatinina: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | Succinato de metilo / creatinina: |
fr-CA | French (Canada) | Méthylsuccinate/Créatinine: |
fr-FR | French (France) | 2-méthylsuccinate/créatinine: |
fr-BE | French (Belgium) | Méthylsuccinate/Créatinine: |
it-IT | Italian (Italy) | Metilsuccinato/Creatinina: Synonyms: Chimica Punto nel tempo (episodio) Rapporto di sostanza |
ko-KR | Korean (Korea, Republic Of) | 메틸숙시네이트/크레아티닌: |
nl-NL | Dutch (Netherlands) | methylsuccinaat/creatinine: Synonyms: kreatinine |
pt-BR | Portuguese (Brazil) | Metilsuccinato/Creatinina: Synonyms: ; |
ru-RU | Russian (Russian Federation) | Метилсукцинат/Креатинин: Synonyms: Количественный Мольная доля; |
tr-TR | Turkish (Turkey) | Metilsüksinat/Kreatinin: Synonyms: SubsOranı |
zh-CN | Chinese (China) | 甲基琥珀酸/肌酐: Synonyms: 2-甲基丁二酸; |
Example Units
Unit | Source |
---|---|
mmol/mol cr | REGENSTRIEF |
mmol/mol{creat} | Example UCUM Units |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=25117-3
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