25133-0
Sarcosine/Creatinine [Molar ratio] in Urine
Active
Part Descriptions
LP15859-9 Sarcosine
Sarcosine is the N-methyl derivative of glycine. It is a natural amino acid found in muscles and other body tissues. In the laboratory, it may be synthesized from chloroacetic acid and methylamine. Sarcosine is found naturally as an intermediate in the metabolism of choline to glycine. Sarcosine is sweet to the taste and dissolves in water. It is used in manufacturing biodegradable surfactants and toothpastes as well as in other applications. Sarcosine is ubiquitous in biological materials and is present in such foods as egg yolks, turkey, ham, vegetables, legumes, etc. Sarcosine is reported to be formed from dietary intake of choline and from the metabolism of methionine and is rapidly degraded to glycine, which, in addition to its importance as a constituent of protein, plays a significant role in various physiological processes as a prime metabolic source of components of living cells such as glutathione, creatine, purines and serine.
Sarcosinemia can result from severe folate deficiency because of the folate requirement for the conversion of sarcosine to glycine.
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia, Sarcosine (Wikipedia)
LP15859-9 Sarcosine
An amino acid intermediate in the metabolism of choline.
Source: National Library of Medicine, MeSH 2006
LP15859-9 Sarcosine
High levels of sarcosine may occur as a result of vitamin B2 insufficiency as vitamin B2 is required to metabolize sarcosine. Information from Metamatrix Clinical Laboratory 2006 12 01.
Source: Regenstrief Institute
LP32035-5 Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas.
Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.)
Source: Human Metabolome Database, Creatinine
Fully-Specified Name
- Component
- Sarcosine/Creatinine
- Property
- SRto
- Time
- Pt
- System
- Urine
- Scale
- Qn
- Method
Additional Names
- Short Name
- Sarcosine/Creat Ur-sRto
- Display Name
- Sarcosine/Creatinine (U) [Molar ratio]
- Consumer Name Alpha Get Info
- Sarcosine/Creatinine, Urine
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.00
- Last Updated
- Version 2.73
- Order vs. Observation
- Observation
- Common Test Rank Get Info
- 12561
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 74991-1 | Amino acids panel [Molar ratio] - Urine |
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG35333-0 | Sarcosine/Creatinine| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-AT | German (Austria) | Synonyms: Sarcosin/Kreatinin-Ratio /U |
| es-AR | Spanish (Argentina) | sarcosina/creatinina: |
| es-ES | Spanish (Spain) | Sarcosina/Creatinina: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Sarcosina / Creatinina: |
| fr-CA | French (Canada) | Sarcosine/Créatinine: |
| fr-FR | French (France) | Sarcosine/créatinine: |
| fr-BE | French (Belgium) | Sarcosine/Créatinine: |
| it-IT | Italian (Italy) | Sarcosina/Creatinina: Synonyms: Chimica Punto nel tempo (episodio) Rapporto di sostanza |
| ko-KR | Korean (Korea, Republic Of) | 사르코신/크레아티닌: |
| nl-NL | Dutch (Netherlands) | sarcosine/creatinine: Synonyms: kreatinine |
| pt-BR | Portuguese (Brazil) | Sarcosina/Creatinina: Synonyms: Sar; |
| ru-RU | Russian (Russian Federation) | Саркозин/Креатинин: Synonyms: Количественный Мольная доля; |
| tr-TR | Turkish (Turkey) | Sarkozin/Kreatinin: Synonyms: SubsOranı |
| zh-CN | Chinese (China) | 肌氨酸/肌酐: Synonyms: CR; |
Example Units
| Unit | Source |
|---|---|
| mmol/mol | eCHN |
| mmol/mol{creat} | Example UCUM Units |
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LOINC Copyright
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