26512-4
Neutrophils/Leukocytes in Cerebral spinal fluid
Active
Part Descriptions
LP14267-6 Neutrophils
Neutrophils are the most common form of white blood cells in healthy adults. Neutrophils are approximately 13 micrometers in diameter and have segmented nuclei with 3-5 lobes that are connected by thin strands of chromatin. (Practical Haematology; Barbara J. Bain, Imelda Bates, Mike A. Laffan,S. Mitchell Lewis; Eleventh edition; 2012) Neutrophils function to fight infection by both engulfing microorganisms and secreting lethal enzymes.
(https://www.ncbi.nlm.nih.gov/pubmedhealth/PMHT0022058/) They are produced in the bone marrow and their primary function is to fight infection. Neutrophil numbers increase in the blood in response to acute bacterial infection, inflammation, necrosis or chronic myelogenous leukemia. Neutrophil levels are decreased in the following conditions: aplastic anemia, autoimmune disorder, cancer, chemotherapy, myelodysplastic syndrome and during a negative reaction to drugs. PMID: 24050624 [MedlinePlus Encyclopedia:19864]
Source: Regenstrief LOINC
LP157588-7 Leukocytes
Leukocytes or white blood cells (WBCs) are immune cells that fight infection, neoplasms and other inflammatory conditions, and mediate allergic responses. There are five types of WBCs normally present in the circulation that are all derived from a similar stem cell in the bone marrow. The five type of WBCs are divided into two groups based on the presence or absence of granules in the cytoplasm. The granulocytes include the neutrophils, basophils and eosinophils. The non-granulocytes include the lymphocytes and the monocytes. The neutrophils fight infection by ingesting and digesting bacteria. Eosinophils and basophils respond to allergic reactions and are capable of ingesting antigen-antibody complexes. Monocytes phagocytose bacteria and release interferon to stimulate the immune system. Lymphocytes are divided into T-cells and B-cells. T-cell immunity is cellular and involves the activation of phagocytes and B-cell immunity uses antibodies to fight infection. Both elevated and low leukocyte counts can be markers of infection and malignancy, and low leukocyte counts are associated with a variety of primary and secondary immunodeficiencies, depending on the WBC type(s) that are out of range. (Mosby's manual of diagnostic and laboratory tests, Kathleen Deska Pagana; Timothy James Pagana, Elsevier St. Louis, Mo ©2010)
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Neutrophils/Leukocytes
- Property
- NFr
- Time
- Pt
- System
- CSF
- Scale
- Qn
- Method
Additional Names
- Long Common Name
- Neutrophils/Leukocytes in Cerebral spinal fluid
- Short Name
- Neutrophils NFr CSF
- Display Name
- Neutrophils/Leukocytes (CSF)
- Consumer Name Alpha Get Info
- Neutrophils/White Blood Cells, Spinal fluid
Basic Attributes
- Class
- HEM/BC
- Type
- Laboratory
- First Released
- Version 2.00
- Last Updated
- Version 2.79 (NAM)
- Change Reason
- Release 2.79: COMPONENT: Triggered by Coll w SCT: This is a specific fraction case where the denominator is percentage or /100. Because the logic is that the percentage piece is captured by Property: NFr (Numeric Fraction), and by Unit: %, therefore, it is redundant to include "100" in the component;
- Order vs. Observation
- Observation
- Common Test Rank Get Info
- 2474
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 54230-8 | Cell count and Diff panel with Gluc and Prot - Cerebral spinal fluid |
| 34564-5 | Cell count and Differential panel - Cerebral spinal fluid |
| 29584-0 | Differential panel - Cerebral spinal fluid |
| 88842-0 | Microbiology CNAMTS panel - Cerebral spinal fluid |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-DE | German (Germany) | Neutrophile/Leukozyten: Synonyms: Zerebrospinalflüssigkeit |
| de-AT | German (Austria) | Synonyms: Neutroph.Gran.rel/L |
| el-GR | Greek (Greece) | Ουδετερόφιλα/Λευκοκύτταρα: Synonyms: NFr |
| es-AR | Spanish (Argentina) | neutrófilos/100 leucocitos: |
| es-ES | Spanish (Spain) | Neutrófilos/Leucocitos: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Neutrófilos / 100 leucocitos: |
| fr-CA | French (Canada) | Neutrophiles/Leucocytes: |
| fr-FR | French (France) | Polynucléaires neutrophiles/100 leucocytes: |
| it-IT | Italian (Italy) | Neutrofili/Leucociti: Synonyms: Ematologia (coagulazione) conta differenziale Frazione numerica Liquido cerebrospinale Punto nel tempo (episodio) |
| ko-KR | Korean (Korea, Republic Of) | 호중구/100 백혈구: |
| nl-NL | Dutch (Netherlands) | neutrofielen/leukocyten: |
| pl-PL | Polish (Poland) | Neutrofile/leukocyty: Synonyms: Leukocyty Neutrofile |
| pt-BR | Portuguese (Brazil) | Neutrófilos/100 leucócitos: Synonyms: PNM; |
| ru-RU | Russian (Russian Federation) | Нейтрофилы/Лейкоциты: Synonyms: Количественный Количество отношение Точка во времени; |
| tr-TR | Turkish (Turkey) | Nötrofiller/Lökosit: |
| zh-CN | Chinese (China) | 嗜中性粒细胞/白细胞: Synonyms: CSF CSF; |
Example Units
| Unit | Source |
|---|---|
| % | Example UCUM Units |
| % | REGENSTRIEF |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=26512-4
LOINC Copyright
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