Version 2.78

Part Description

LP15747-6   Gentamicin
Gentamicin is an aminoglycoside antibiotic, which has a bactericidal mode of action binding to the ribosome and various ribozymes to inhibit protein synthesis. Gentamicin is a hydrophilic molecule and is considered to have limited capacity to penetrate eukaryotic cells. Administered intravenously or intramuscularly, gentamicin is used to treat many bacterial infections, particularly gram-negative organisms such as meningitis, and infections of the blood, abdomen, lungs, skin, bones, joints and urinary tract, and is often used to treat severe cases of tularemia and the plague. The effect of gentamicin is mediated through the production of reactive oxygen species (ROS), which causes destablization of iron-sulfur (Fe-S) clusters and generates toxic, bactericidal compounds through the Fenton reaction. Gentamicin may cause kidney, nerve and severe hearing problems. More common side effects include nausea, headache, fever, rash and hoarseness. PMID: 26503658 [MedlinePlus Drug:a682275] Source: Regenstrief LOINC

Fully-Specified Name

Component
Gentamicin
Property
Susc
Time
Pt
System
Isolate
Scale
OrdQn
Method
Agar diffusion

Additional Names

Short Name
Gentamicin Islt KB
Display Name
Gentamicin Disk diffusion (KB) [Susc]
Consumer Name Alpha Get Info
Susceptibility to Gentamicin

Basic Attributes

Class
ABXBACT
Type
Laboratory
First Released
Version 1.0
Last Updated
Version 2.73
Order vs. Observation
Observation
Common Test Rank Get Info
3036

Member of these Panels

LOINC Long Common Name
50546-1 Bacterial susceptibility panel by Disk diffusion (KB)

Member of these Groups Get Info

LOINC Group Group Name
LG41057-7 GentamicinSusc|Isolate

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Gentamicin:Empfindlichkeit (Mikroorganismen):Zeitpunkt:Isolat:Ordinal oder Quantitativ:Agardiffusionstest
es-AR Spanish (Argentina) gentamicina:susceptibilidad:punto en el tiempo:cepa clínica:ordinal o cuantitativo:difusión en agar
es-ES Spanish (Spain) Gentamicina:Susceptibilidad:Punto temporal:Aislado:Ordinal Cuantitativo:Difusión en disco; Kirby Bauer
es-MX Spanish (Mexico) Gentamicina:Susceptibilidad (microorganismos):Punto temporal:Aislado:Ordinal Cuantitativo:Difusión de disco (KB)
fr-CA French (Canada) Gentamicine:Susceptibilité:Temps ponctuel:Isolat:Quantitatif ou ordinal:Diffusion sur plaques
fr-FR French (France) Gentamicine:Sensibilité:Ponctuel:Isolat:Alphanumérique:Diffusion gel Agar
fr-BE French (Belgium) Gentamicine:Susceptibilité:Temps ponctuel:Isolat:Quantitatif ou ordinal:Diffusion sur plaques
Synonyms: Diffusion en agar, précipitation en agar
it-IT Italian (Italy) Gentamicina:Susc:Pt:Isolato:OrdQn:Agar diffusione
Synonyms: Disco diffusione (KB) Kirby-Bauer Punto nel tempo (episodio) Sensibilità (microrganismi) Suscettibilità agli antibiotici
ko-KR Korean (Korea, Republic Of) 겐타마이신:감수성:검사시점:분리주:정량 or 순위척도:우무확산
nl-NL Dutch (Netherlands) gentamicine:gevoeligheid:moment:isolaat:ordinaal-kwantitatief:agardiffusie
pt-BR Portuguese (Brazil) Gentamicina:Susc:Pt:Isolado:OrdQn:Difusão em agar (disco)
Synonyms: c213; Gent; Garamycin; Genj; Genirr; Susceptibility; Susceptibilty; Sus; Suscept; Susceptibilities; Point in time; Random; Islt; Isol; KB; Kirby-bauer; Disk diffusion; ANTIBIOTIC SUSCEPTIBILITIES
tr-TR Turkish (Turkey) Gentamisin:Duyr:Zmlı:İzolat:SrlKant:Agar difüzyon
zh-CN Chinese (China) 庆大霉素:抗生素敏感性:时间点:分离株:定量型或序数型:琼脂扩散法
Synonyms: KB 法;Kirby-bauer 法;平皿扩散;平皿扩散法;琼脂平皿扩散;琼脂平皿扩散法;琼脂扩散;琼脂板扩散;琼脂板扩散法 分离物;分离菌;分离菌株;隔离种群 抗生素敏感性(微生物);敏感性;某种抗微生物制剂对于某个分离株的影响;药物敏感性;药物敏感性(微生物) 抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类 时刻;随机;随意;瞬间 正泰霉素;艮他霉素

Example Units

Unit Source
mm Example UCUM Units
mm REGENSTRIEF

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=268-3