29506-3

2-Oxoadipate/Creatinine [Molar ratio] in Urine

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Part Descriptions

LP18408-2 2-Oxoadipate
α-Ketoadipic acid (or 2-oxoadipate) is an intermediate in the metabolism of lysine. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

LP18408-2 2-Oxoadipate
2-Oxoadipic acid is produced from lysine in the cytosol of cells via the saccharopine and the pipecolic acid pathways. Catabolites of hydroxylysine and tryptophan enter these pathways as 2-aminoadipic- -semialdehyde and 2-oxoadipate, respectively. In the matrix of mitochondria, 2-oxoadipate is decarboxylated to glutaryl-CoA by the 2-oxoadipate dehydrogenase complex and then converted to acetyl-CoA. 2-Oxoadipic aciduria is an in-born error of metabolism of lysine, tryptophan, and hydroxylysine, in which abnormal quantities of 2-aminoadipic acid are found in body fluids along with 2-oxoadipic acid. Patients with 2-Oxoadipic acidemias are mentally retarded with hypotonia or seizures. 2-Oxoadipic Aciduria can occur in patients with Kearns-Sayre Syndrome, a progressive disorder with onset prior to 20 years of age in which multiple organ systems are affected, including progressive external ophthalmoplegia, retinopathy, and the age of onset, and these are associated classically with abnormalities in cardiac conduction, cerebellar signs, and elevated cerebrospinal fluid protein. PMID: 10655159, PMID: 16183823, PMID: 11083877 Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database

LP32035-5 Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas. Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, Creatinine

Fully-Specified Name

Component: 2-Oxoadipate/Creatinine
Property: SRto
Time: Pt
System: Urine
Scale: Qn
Method

Additional Names

Long Common Name: 2-Oxoadipate/Creatinine [Molar ratio] in Urine
Short Name: 2-Oxoadipate/Creat Ur-sRto
Display Name: 2-Oxoadipate/Creatinine (U) [Molar ratio]
Consumer Name Alpha Get Info: 2-Oxoadipate/Creatinine, Urine

Basic Attributes

Class: CHEM
Type: Laboratory
First Released: Version 2.03
Last Updated: Version 2.73
Order vs. Observation: Observation
Common Test Rank Get Info: 11833

Member of these Panels

LOINC	Long Common Name
48797-5	Organic acids panel - Urine

Language Variants Get Info

Tag	Language	Translation
de-DE	German (Germany)	2-Oxoadipat/Creatinin:Stoffmengenverhältnis:Zeitpunkt:Urin:Quantitativ:
es-AR	Spanish (Argentina)	2-oxoadipato/creatinina:relación de concentración de la sustancia:punto en el tiempo:orina:cuantitativo:
es-ES	Spanish (Spain)	2-Oxoadipato/Creatinina:Relacion de Sustancia:Punto temporal:Orina:Qn: Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	2-oxoadipato / creatinina:Proporción de sustancia:Punto temporal:Orina:Cuantitativo:
fr-CA	French (Canada)	2-oxoadipate/Créatinine:Ratio de substance:Temps ponctuel:Urine:Quantitatif:
fr-FR	French (France)	2-oxoadipate/créatinine:Moles ratio:Ponctuel:Urine:Numérique:
fr-BE	French (Belgium)	2-oxoadipate/Créatinine:Ratio de substance:Temps ponctuel:Urine:Quantitatif:
it-IT	Italian (Italy)	2-Ossoadipato/Creatinina:Srto:Pt:Urine:Qn: Synonyms: Chimica Punto nel tempo (episodio) Rapporto di sostanza
ko-KR	Korean (Korea, Republic Of)	2-옥소아디페이트/크레아티닌:물질구성비:검사시점:뇨:정량:
nl-NL	Dutch (Netherlands)	2-oxoadipaat/creatinine:molaire verhouding:moment:urine:kwantitatief: Synonyms: kreatinine
pt-BR	Portuguese (Brazil)	2-Oxoadipato/Creatinina:SCrto:Pt:Urina:Qn: Synonyms: ; 2Oxo-adipate; 2-oxoadipic acid; Creat; CR; 2Oxo-adipate; sRto; Substance concentration ratio; Point in time; Random; Ur; UR; Urn; UA; Quantitative; QNT; Quant; Quan; II; Chemistry; UCr
ru-RU	Russian (Russian Federation)	2-Оксоадипат/Креатинин:МольОтн:ТчкВрм:Моча:Колич: Synonyms: Количественный Мольная доля;Молярная доля;Отношение концентраций Точка во времени;Момент
tr-TR	Turkish (Turkey)	2-Okzoadipat/Kreatinin:SOrn:Zmlı:İdrar:Kant: Synonyms: SubsOranı
zh-CN	Chinese (China)	2-氧代己二酸/肌酐:物质的量比率:时间点:尿液:定量型: Synonyms: 2Oxo-己二酸 Ⅱ CR;Creat;肌氨酸酐;肌酸内酰胺;肌酸酐 II UCr 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类可用数量表示的;定量性;数值型;数量型;连续数值型标尺尿;小便;下泉尿液肌酐尿液肌酸酐尿肌酸酐时刻;随机;随意;瞬间物质的量比值;物质的量比;摩尔比;摩尔比率;摩尔比值肌酸内酰胺

Example Units

Unit	Source
mmol/mol cr	REGENSTRIEF
mmol/mol{creat}	Example UCUM Units

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