Version 2.78

Part Descriptions

LP15301-2   3-Hydroxyisovalerate
3-Hydroxyisovaleric acid is a normal human metabolite excreted in the urine. Elevated levels of this compound are found in several inherited disorders such as Dihydrolipoamide dehydrogenase Deficiency, 3-Methylcrotonyl-CoA carboxylase 1 deficiency, 3-Hydroxy-3-methylglutaryl-CoA lyase deficiency (3-hydroxy-3-methylglutaryl -CoA lyase Deficiency, Biotinidase deficiency multiple carboxylase deficiency late-onset , Late onset multiple carboxylase deficiency, HolMcarboxylase synthetase deficiency, 3-Methylcrotonyl-CoA carboxylase 2 deficiency. 3-Hydroxyisovaleric acid is also elevated in smokers, in subjects undergoing long-term anticonvulsant therapy with carbamazepine and/or phenytoin. These levels are elevated due to impairment of renal reclamation of biotin. Levels may also be increased from prolonged consumption of raw egg-whites PMID: 16895887, PMID: 9523856, PMID: 15447901, PMID: 9176832, [OMIM: 210210], [OMIM: 253270], [OMIM: 600529], [OMIM: 253260], [OMIM: 246450], [OMIM: 210200], [OMIM: 238331] Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, Human Metabolome Database

LP32035-5   Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas. Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, Creatinine

Fully-Specified Name

Component
3-Hydroxyisovalerate/Creatinine
Property
SRto
Time
Pt
System
Urine
Scale
Qn
Method

Additional Names

Short Name
3OH-Isovalerate/Creat Ur-sRto
Display Name
3-Hydroxyisovalerate/Creatinine (U) [Molar ratio]
Consumer Name Alpha Get Info
3-Hydroxyisovalerate/Creatinine, Urine

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.03
Last Updated
Version 2.73
Order vs. Observation
Observation
Common Test Rank Get Info
11525

Member of these Panels

LOINC Long Common Name
48797-5 Organic acids panel - Urine

Member of these Groups Get Info

LOINC Group Group Name
LG35772-9 3-Hydroxyisovalerate/Creatinine|SRto|Urine

Language Variants Get Info

Tag Language Translation
de-AT German (Austria) Synonyms: 3-OH-Isovaleriansäure/Kreatinin-Ratio /U
de-DE German (Germany) 3-Hydroxyisovalerat/Creatinin:Stoffmengenverhältnis:Zeitpunkt:Urin:Quantitativ:
es-AR Spanish (Argentina) 3-hidroxiisovalerato/creatinina:relación de concentración de la sustancia:punto en el tiempo:orina:cuantitativo:
es-ES Spanish (Spain) 3-Hidroxiisovalerato/Creatinina:Relacion de Sustancia:Punto temporal:Orina:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) 3-hidroxiisovalerato / creatinina:Proporción de sustancia:Punto temporal:Orina:Cuantitativo:
fr-CA French (Canada) 3-hydroxyisovalérate/Créatinine:Ratio de substance:Temps ponctuel:Urine:Quantitatif:
fr-FR French (France) 3-hydroxyisovalérate/créatinine:Moles ratio:Ponctuel:Urine:Numérique:
fr-BE French (Belgium) 3-hydroxyisovalérate/Créatinine:Ratio de substance:Temps ponctuel:Urine:Quantitatif:
it-IT Italian (Italy) 3-Idrossiisovalerato/Creatinina:Srto:Pt:Urine:Qn:
Synonyms: Chimica Punto nel tempo (episodio) Rapporto di sostanza
ko-KR Korean (Korea, Republic Of) 3-하이드록시이소발레레이트/크레아티닌:물질구성비:검사시점:뇨:정량:
nl-NL Dutch (Netherlands) 3-hydroxyisovaleraat/creatinine:molaire verhouding:moment:urine:kwantitatief:
Synonyms: kreatinine
pt-BR Portuguese (Brazil) 3-Hidroxiisovalerato/Creatinina:SCrto:Pt:Urina:Qn:
Synonyms: ; 3OH-Isovalerate; 3-hydroxy-isovalerate; 3-HIA; 3-hydroxyisovaleric acid; Creat; CR; 3OH-Isovalerate; sRto; Substance concentration ratio; Point in time; Random; Ur; UR; Urn; UA; Quantitative; QNT; Quant; Quan; III; Chemistry; UCr
ru-RU Russian (Russian Federation) 3-Гидроксиизовалерат/Креатинин:МольОтн:ТчкВрм:Моча:Колич:
Synonyms: Количественный Мольная доля;Молярная доля;Отношение концентраций Точка во времени;Момент
tr-TR Turkish (Turkey) 3-Hidroksiizovalerat/Kreatinin:SOrn:Zmlı:İdrar:Kant:
Synonyms: SubsOranı
zh-CN Chinese (China) 3-羟基异戊酸/肌酐:物质的量比率:时间点:尿液:定量型:
Synonyms: 3-HIA;3OH-异戊酸;3-羟基-异戊酸 Ⅲ CR;Creat;肌氨酸酐;肌酸内酰胺;肌酸酐 III UCr 三 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 叁 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 尿;小便;下泉 尿液肌酐 尿液肌酸酐 尿肌酸酐 时刻;随机;随意;瞬间 物质的量比值;物质的量比;摩尔比;摩尔比率;摩尔比值 肌酸内酰胺

Example Units

Unit Source
mmol/mol cr REGENSTRIEF
mmol/mol{creat} Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=29514-7