29860-4
Cardiolipin Ab [Presence] in Serum
Active
Part Descriptions
LP14126-4 Cardiolipin
Cardiolipin (bisphosphatidyl glycerol) is an important component of the inner mitochondrial membrane, where it constitutes about 20% of the total lipid. It is typically present in metabolically active cells of the heart and skeletal muscle. It has also been observed in certain bacterial membranes. It serves as an insulator and stabilizes the activity of protein complexes important to the electron transport chain. Cardiolipin is a double phospholipid because it has four fatty acid tails, instead of the usual two. Barth syndrome, a rare genetic disorder, is a mutation in the gene coding for tafazzin, an enzyme involved in the biosynthesis of cardiolipin. Females heterozygous for the trait are not affected. Individuals with this condition have abnormal mitochondria and they cannot sustain adequate production of ATP. Cardiomyopathy and general weakness are common to these patients.
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia, Cardiolipin (Wikipedia)
LP21333-7 Cardiolipin Ab
Anti-cardiolipin antibodies (ACA) are antibodies often directed against cardiolipin and found in several diseases including syphilis, antiphospholipid syndrome, livedoid vasculitis, vertebrobasilar insufficiency, Behçet's syndrome, idiopathic spontaneous abortion, and systemic lupus erythematosus(SLE). They are a form of anti-mitochondrial antibody. In SLE, The anti-DNA antibodies and anti-cardiolipin act independently. In rheumatoid arthritis with systemic sclerosis (scleroderma) these antibodies may tie two conditions together.
Anti-cardiolipin antibodies can be classified in two ways:
As IgM, IgG or IgA
As β2-glycoprotein dependent or independent
In autoimmune disease ACA are beta-2 glycoprotein dependent
syphilis ACA are beta-2 glycoprotein independent and can be assayed using the VDRL test
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia, Wikipedia
Fully-Specified Name
- Component
- Cardiolipin Ab
- Property
- PrThr
- Time
- Pt
- System
- Ser
- Scale
- Ord
- Method
Additional Names
- Short Name
- Cardiolipin Ab Ser Ql
- Display Name
- Cardiolipin Ab Ql (S)
- Consumer Name Alpha Get Info
- Cardiolipin antibody, Blood
Example Answer List: LL360-9
Source: Regenstrief Institute| Answer | Code | Score | Answer ID |
|---|---|---|---|
| PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) | LA6576-8 | ||
| NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) | LA6577-6 |
Basic Attributes
- Class
- COAG
- Type
- Laboratory
- First Released
- Version 2.04
- Last Updated
- Version 2.73
- Change Reason
- The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 4872
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-DE | German (Germany) | Cardiolipin Ak: |
| es-AR | Spanish (Argentina) | anticuerpo anticardiolipina: |
| es-ES | Spanish (Spain) | Cardiolipinas Anticuerpos: |
| es-MX | Spanish (Mexico) | Cardiolipin Ab: |
| et-EE | Estonian (Estonia) | Kardiolipiin antikehad: Synonyms: Järgarvuline Juhuslik Seerum |
| fr-CA | French (Canada) | Cardiolipine, Ac: |
| fr-FR | French (France) | Cardiolipine anticorps: |
| fr-BE | French (Belgium) | Cardiolipine Ac: Synonyms: Anticorps |
| it-IT | Italian (Italy) | Cardiolipina Ab: Synonyms: anticorpo Presenza o Soglia Punto nel tempo (episodio) Siero Studio di coagulazione |
| ko-KR | Korean (Korea, Republic Of) | 카디오리핀 항체: |
| nl-NL | Dutch (Netherlands) | cardiolipine As: Synonyms: antistof; |
| pt-BR | Portuguese (Brazil) | Cardiolipina Ac: Synonyms: ACA; |
| ru-RU | Russian (Russian Federation) | Кардиолипин Ат: Synonyms: Антитело Порядковый Сыворотка Точка во времени; |
| tr-TR | Turkish (Turkey) | Kardiyolipin Ab: Synonyms: Ak Mevcut |
| zh-CN | Chinese (China) | 心磷脂 抗体: Synonyms: Ab; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=29860-4
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.
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LOINC Copyright
Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright