34543-9
Bilirubin direct and total panel [Mass/volume] - Serum or Plasma
Active
1968-7 Bilirubin.direct [Mass/volume] in Serum or Plasma
Term Description
Except when measured by differential light absorption, direct bilirubin included glucuronidated and albumin bound (delta) bilirubin;Method can be WET CHEMISTRY or DRY SLIDE = (TBIL-Bu)
Source: Regenstrief LOINC
Part Descriptions
LP15445-7 Bilirubin.glucuronidated+Bilirubin.albumin bound
Bilirubin is an orange-yellow pigment produced by the normal breakdown of heme, a component of the hemoglobin found in red blood cells. It is processed by the liver and excreted in bile. Conditions that cause red blood cell breakdown or interfere with liver or bile processing can cause elevated levels of bilirubin. Bilirubin exists in many forms. Non-glucuronidated bilirubin (also called unconjugated or indirect) is the breakdown product of heme and is not water-soluble. Hemolytic anemias, which cause increased red blood cell breakdown, are one cause of elevated non-glucuronidated bilirubin. Glucuronidated bilirubin (also called conjugated) is a water-soluble form of bilirubin that is made in the liver by the addition of sugar molecules to non-glucuronidated bilirubin. Conditions that affect liver function (such as hepatitis, cirrhosis and liver tumors) or physically block the bile ducts (such as gallstones) can cause elevated levels of glucuronidated bilirubin. A third form of bilirubin is that which is bound to albumin, and it is also known as delta bilirubin because it was originally identified based on the unexpected difference between the total bilirubin level and the level of glucuronidated plus non-glucuronidated bilirubin in some patient samples. Prior to the discovery of albumin-bound bilirubin, the term "direct" bilirubin was used as a synonym for glucuronidated bilirubin, but direct bilirubin is actually glucuronidated plus delta bilirubin (bilirubin covalently bound to albumin).
Source: Regenstrief LOINC
Reference Information
| Type | Source | Reference |
|---|---|---|
| Webcontent | Lab Tests Online®Copyright Copyright © 2021 Lab Tests Online. All rights reserved. | Bilirubin |
Observation Required in Panel
Required
Type of Entry
Question expects user entry - requires response [Q]
Fully-Specified Name
- Component
- Bilirubin.glucuronidated+Bilirubin.albumin bound
- Property
- MCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Panel Name
- Short Name
- Bilirub Direct SerPl-mCnc
- Display Name
- Bilirubin.direct [Mass/Vol]
- Consumer Name Alpha Get Info
- Bilirubin.direct, Blood
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 1.0
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 131
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 34543-9 | Bilirubin direct and total panel [Mass/volume] - Serum or Plasma |
| 24324-6 | Hepatic function 1996 panel - Serum or Plasma |
| 24325-3 | Hepatic function 2000 panel - Serum or Plasma |
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG6165-7 | Bilirubin.glucuronidated+Bilirubin.albumin bound| |
| LG43215-9 | Bilirubin.glucuronidated+Bilirubin.albumin bound| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-DE | German (Germany) | Bilirubin.glucuronidiert+Bilirubin.Albumin gebunden: Synonyms: Bili |
| de-AT | German (Austria) | Synonyms: Bilirubin, direktes |
| el-GR | Greek (Greece) | Χολερυθρίνη συνδεδεμένη με γλυκουρονίδια+Χολερυθρίνη συνδεδεμένη με λευκωματίνη: |
| es-MX | Spanish (Mexico) | Bilirrubina glucuronidada + Bilirrubina ligada a albúmina: |
| es-ES | Spanish (Spain) | Bilirrubina conjugada + bilirrubina unida a albúmina: Synonyms: Cuantitativo |
| es-AR | Spanish (Argentina) | bilirrubina.conjugada+bilirrubina.ligada a albúmina: |
| fr-CA | French (Canada) | Bilirubine.glucuroconjuguée+bilirubine.liée à l'albumine: |
| fr-BE | French (Belgium) | Bilirubine.glucuroconjuguée+bilirubine.liée ? l'albumine: |
| fr-FR | French (France) | Bilirubine conjuguée+liée à l'albumine: |
| it-IT | Italian (Italy) | Bilirubina.glucuronidata+Bbilirubina.albumina legata: Synonyms: Chimica Concentrazione di Massa Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
| ko-KR | Korean (Korea, Republic Of) | 글루쿠론산화 빌리루빈+알부민 결합 빌리루빈: |
| nl-NL | Dutch (Netherlands) | bilirubine.geglucuronideerd + bilirubine.albuminegebonden: |
| pl-PL | Polish (Poland) | Bilirubina, glukuronidowana+bilirubina, związana z albuminą: |
| pt-BR | Portuguese (Brazil) | Bilirrubina.glicuronizada+Bilirrubina.ligada a albumina: Synonyms: ; |
| ru-RU | Russian (Russian Federation) | Билирубин.глюкоронат+Билирубин.альбумин связанный: Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени; |
| tr-TR | Turkish (Turkey) | Bilirubin.glukuronize+Bilirubin.albumine bağlı: |
| zh-CN | Chinese (China) | 胆红素.葡糖醛酸化+胆红素.白蛋白结合型: Synonyms: Alb; |
Example Units
| Unit | Source |
|---|---|
| mg/dL | Example UCUM Units |
| mg/dL | REGENSTRIEF |
1975-2 Bilirubin.total [Mass/volume] in Serum or Plasma
Term Description
Method can be DIRECT SPECTOPHOTOMETRY, WET CHEMISTRY or DRY SLIDE (TBIL)
Source: Regenstrief LOINC
Part Descriptions
LP15448-1 Bilirubin
Bilirubin is an orange-yellow pigment produced by the normal breakdown of heme, a component of the hemoglobin found in red blood cells. It is processed by the liver and excreted in bile. Conditions that cause red blood cell breakdown or interfere with liver or bile processing can cause elevated levels of bilirubin. Bilirubin exists in many forms. Non-glucuronidated bilirubin (also called unconjugated or indirect) is the breakdown product of heme and is not water-soluble. Hemolytic anemias, which cause increased red blood cell breakdown, are one cause of elevated non-glucuronidated bilirubin. Glucuronidated bilirubin (also called conjugated) is a water-soluble form of bilirubin that is made in the liver by the addition of sugar molecules to non-glucuronidated bilirubin. Conditions that affect liver function (such as hepatitis, cirrhosis and liver tumors) or physically block the bile ducts (such as gallstones) can cause elevated levels of glucuronidated bilirubin. A third form of bilirubin is that which is bound to albumin, and it is also known as delta bilirubin because it was originally identified based on the unexpected difference between the total bilirubin level and the level of glucuronidated plus non-glucuronidated bilirubin in some patient samples. Prior to the discovery of albumin-bound bilirubin, the term "direct" bilirubin was used as a synonym for glucuronidated bilirubin, but direct bilirubin is actually glucuronidated plus delta bilirubin (bilirubin covalently bound to albumin).
Source: Regenstrief LOINC
Reference Information
| Type | Source | Reference |
|---|---|---|
| Mapping Guidance | Regenstrief Help | Total bilirubin = direct + indirect Mapper’s Guide for the Top 2000 plus LOINC Laboratory Observations |
| Webcontent | Lab Tests Online®Copyright Copyright © 2021 Lab Tests Online. All rights reserved. | Bilirubin |
Observation Required in Panel
Required
Type of Entry
Question expects user entry - requires response [Q]
Fully-Specified Name
- Component
- Bilirubin
- Property
- MCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Panel Name
- Short Name
- Bilirub SerPl-mCnc
- Display Name
- Bilirubin [Mass/Vol]
- Consumer Name Alpha Get Info
- Bilirubin, Blood
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 1.0
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 22
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 34543-9 | Bilirubin direct and total panel [Mass/volume] - Serum or Plasma |
| 98153-0 | Child-Pugh panel |
| 24322-0 | Comprehensive metabolic 1998 panel - Serum or Plasma |
| 24323-8 | Comprehensive metabolic 2000 panel - Serum or Plasma |
| 24324-6 | Hepatic function 1996 panel - Serum or Plasma |
| 24325-3 | Hepatic function 2000 panel - Serum or Plasma |
| 48796-7 | Hepatitis C virus FibroSURE panel - Serum or Plasma |
| 78698-8 | Liver fibrosis score panel - Serum or Plasma Calculated by HepaScore |
| 54232-4 | Metabolic panel.large animal - Serum or Plasma |
| 54233-2 | Metabolic panel.small animal - Serum or Plasma |
| 93691-4 | Nonalcoholic steatohepatitis and fibrosis panel - Serum or Plasma |
| 96789-3 | Sequential Organ Failure Assessment SOFA |
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG6199-6 | Bilirubin| |
| LG49848-1 | Bilirubin| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-AT | German (Austria) | Synonyms: Bilirubin |
| de-DE | German (Germany) | Bilirubin: |
| el-GR | Greek (Greece) | Χολερυθρίνη: |
| es-AR | Spanish (Argentina) | bilirrubina: |
| es-ES | Spanish (Spain) | Bilirrubina: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Bilirrubina: |
| et-EE | Estonian (Estonia) | Bilirubiin: Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma |
| fr-FR | French (France) | Bilirubine: |
| fr-BE | French (Belgium) | Bilirubine: |
| fr-CA | French (Canada) | Bilirubine: |
| it-IT | Italian (Italy) | Bilirubina: Synonyms: Chimica Concentrazione di Massa Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
| ko-KR | Korean (Korea, Republic Of) | 빌리루빈: |
| nl-NL | Dutch (Netherlands) | bilirubine: |
| pl-PL | Polish (Poland) | Bilirubina: |
| pt-BR | Portuguese (Brazil) | Bilirrubina: Synonyms: ; |
| ru-RU | Russian (Russian Federation) | Билирубин: Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени; |
| tr-TR | Turkish (Turkey) | Bilirubin: |
| uk-UA | Ukrainian (Ukraine) | Білірубін: Synonyms: Bili; |
| zh-CN | Chinese (China) | 胆红素: Synonyms: TBIL; |
Example Units
| Unit | Source |
|---|---|
| mg/dL | Example UCUM Units |
| mg/dL | REGENSTRIEF |