34671-8
8-Dehydrocholesterol [Mass/volume] in Serum or Plasma
Active
Part Description
LP32687-3 8-Dehydrocholesterol
8-Dehydrocholesterol (8-DHC) elevated concentration is one of the diagnostic biochemical hallmarks of classical Smith-Lemli-Opitz syndrome (SLOS) . Plasma 8-DHC could be only marginally elevated. ( PMID: 16435228) Smith-Lemli-Opitz syndrome (SLOS) is an autosomal recessive condition caused by a defect in cholesterol synthesis (caused by a deficit of 3beta-hydroxysterol-Delta7 reductase). Affected children often have malformations and mental retardation. Autistic behaviors also are evident. In children, the baseline cholesterol, 8-DHC levels, and cholesterol levels following supplementation does not correlate with the presence or severity of autistic symptoms. PMID: 16761297 Accumulation of 8-dehydrocholesterol in Amniotic fluid is diagnostic for SLOS. PMID: 16231320
Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.)
Source: Human Metabolome Database, 8-Dehydrocholesterol
Fully-Specified Name
- Component
- 8-Dehydrocholesterol
- Property
- MCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Short Name
- 8-DHC SerPl-mCnc
- Display Name
- 8-Dehydrocholesterol [Mass/Vol]
- Consumer Name Alpha Get Info
- 8-Dehydrocholesterol, Blood
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.11
- Last Updated
- Version 2.44
- Order vs. Observation
- Both
Member of these Groups Get Info
LOINC Group | Group Name |
---|---|
LG42097-2 | 8-Dehydrocholesterol| |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-AR | Spanish (Argentina) | 8-dehidrocolesterol: |
es-ES | Spanish (Spain) | 8-Dehidrocolesterol: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | 8-deshidrocolesterol: |
et-EE | Estonian (Estonia) | 8-dehüdrokolesterool: Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma |
fr-FR | French (France) | 8-déhydrocholestérol: |
fr-BE | French (Belgium) | 8-Dehydrocholestérol: |
fr-CA | French (Canada) | 8-déhydrocholestérol: |
it-IT | Italian (Italy) | 8-Deidrocolesterolo: Synonyms: Chimica Concentrazione di Massa Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
ko-KR | Korean (Korea, Republic Of) | 8-디하이드로콜레스테롤: |
nl-NL | Dutch (Netherlands) | 8-dehydrocholesterol: |
pl-PL | Polish (Poland) | 8-dehydrocholesterol: |
pt-BR | Portuguese (Brazil) | 8-Dehidrocolesterol: Synonyms: ; |
ru-RU | Russian (Russian Federation) | 8-Дегидрохолестерол: Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени; |
tr-TR | Turkish (Turkey) | 8-Dehidrokolesterol: |
zh-CN | Chinese (China) | 8-脱氢胆固醇: Synonyms: 化学; |
Example Units
Unit | Source |
---|---|
ng/mL | Example UCUM Units |
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