38360-4
Isobutyrylglycine/Creatinine [Mass Ratio] in Urine
Active
Part Descriptions
LP14515-8 Isobutyrylglycine
Isobutyrylglycine is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. However, the excretion of certain acyl glycines is increased in several inborn errors of metabolism. In certain cases the measurement of these metabolites in body fluids can be used to diagnose disorders associated with mitochondrial fatty acid beta-oxidation. Acyl glycines are produced through the action of glycine N-acyltransferase (EC 2.3.1.13) which is an enzyme that catalyzes the chemical reaction: acyl-CoA + glycine < -- > CoA + N-acylglycine Isobutyrylglycine is identified in large amount in urine of patients with isobutyryl-CoA dehydrogenase deficiency. Isobutyryl-CoA dehydrogenase deficiency is a disorder caused by the deficiency of isobutyryl-CoA dehydrogenase that is involved in the catabolism of the branched-chain amino acid valine PMID: 15505379.
Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.)
Source: Human Metabolome Database, Isobutyrylglycine
LP32035-5 Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas.
Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.)
Source: Human Metabolome Database, Creatinine
Fully-Specified Name
- Component
- Isobutyrylglycine/Creatinine
- Property
- MRto
- Time
- Pt
- System
- Urine
- Scale
- Qn
- Method
Additional Names
- Long Common Name
- Isobutyrylglycine/Creatinine [Mass Ratio] in Urine
- Short Name
- Isobutyrylgly/Creat Ur
- Display Name
- Isobutyrylglycine/Creatinine (U) [Mass ratio]
- Consumer Name Alpha Get Info
- Isobutyrylglycine/Creatinine, Urine
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.14
- Last Updated
- Version 2.73
- Order vs. Observation
- Observation
- Common Test Rank Get Info
- 7176
Member of these Panels
LOINC | Long Common Name |
---|---|
50334-2 | Acylglycines panel [Mass Ratio] - Urine |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-AR | Spanish (Argentina) | metanefrina/creatinina: |
es-ES | Spanish (Spain) | Isobutirilglicina/Creatinina: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | Isobutirilglicina / Creatinina: |
et-EE | Estonian (Estonia) | Isobutürüülglütsiin/kreatiniin: Synonyms: Juhuslik Kvantitatiivne Uriin |
fr-CA | French (Canada) | Isobutyrylglycine/Créatinine: |
fr-FR | French (France) | Isobutyrylglycine/créatinine: |
fr-BE | French (Belgium) | Isobutyrylglycine/Créatinine: Synonyms: Rapport de masse |
it-IT | Italian (Italy) | Isobutirilglicina/Creatinina: Synonyms: Chimica Punto nel tempo (episodio) Rapporto di Massa |
ko-KR | Korean (Korea, Republic Of) | 이소부틸글리신/크레아티닌: |
nl-NL | Dutch (Netherlands) | isobutyrylglycine/creatinine: Synonyms: kreatinine |
pt-BR | Portuguese (Brazil) | Isobutirilglicina/Creatinina: Synonyms: ; |
ru-RU | Russian (Russian Federation) | Изобутирилглицин/Креатинин: Synonyms: Количественный Масс отношение Точка во времени; |
tr-TR | Turkish (Turkey) | İzobütirilglisin/Kreatinin: |
uk-UA | Ukrainian (Ukraine) | Ізобутирилгліцин/Креатинін: Synonyms: Chemistry; |
zh-CN | Chinese (China) | 异丁酰甘氨酸/肌酐: Synonyms: CR; |
Example Units
Unit | Source |
---|---|
mcg/mg cr | REGENSTRIEF |
mg/gm cr | REGENSTRIEF |
ug/mg{creat} | Example UCUM Units |
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