38371-1

Xanthine/Creatinine [Molar ratio] in Urine

Active

Part Descriptions

LP15953-0   Xanthine
A purine base found in most body tissues and fluids, certain plants, and some urinary calculi. It is an intermediate in the degradation of adenosine monophosphate to uric acid, being formed by oxidation of hypoxanthine. The methylated xanthine compounds caffeine, theobromine, and theophylline and their derivatives are used in medicine for their bronchodilator effects. (Dorland, 28th ed) Source: National Library of Medicine, MeSH 2006

LP15953-0   Xanthine
Xanthine is a product on the pathway of purine degradation and is converted to uric acid by the action of the xanthine oxidase (xanthine dehydrogenase) enzyme. Some people lack sufficient xanthine oxidase, and thus xanthine cannot be converted to uric acid. This rare genetic disorder is called xanthinuria results from excessive excretion of xanthine into the urine. This disorder can result in urolithiasis and sometimes myopathy from xanthine deposition. Elevated xanthine can also result from allopurinol treatment. Xanthine is also the core chemical component of a group of alkaloids that are commonly used for their effects as mild stimulants and as bronchodilators, notably in treating the symptoms of asthma. Their effects, however, are widespread and their therapeutic range is narrow and so they are not the drug of choice in asthma treatment. Methylated xanthine derivatives include caffeine, theophylline, and theobromine (found mainly in chocolate). These drugs inhibit phosphodiesterase and antagonise adenoine. Source: Regenstrief LOINC

LP32035-5   Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas. Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, Creatinine

Fully-Specified Name

Component

Xanthine/Creatinine

Property

SRto

Time

Pt

System

Urine

Scale

Qn

Method

Additional Names

Short Name

Xanthine/Creat Ur-sRto

Display Name

Xanthine/Creatinine (U) [Molar ratio]

Consumer Name Alpha Get Info

Xanthine/Creatinine, Urine

Basic Attributes

Class

CHEM

Type

Laboratory

First Released

Version 2.14

Last Updated

Version 2.73

Order vs. Observation

Both

Common Test Rank Get Info

7816

Member of these Panels

Language Variants Get Info

Related Names

• Chemistry
• CR
• Crea
• Creat
• Point in time
• QNT
• Quan
• Quant
• Quantitative
• Random
• Scrto
• Substance concentration ratio
• Substance ratio
• UA
• UCr
• UR
• Urn

Example Units

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CodeSystem lookup

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Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2024, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.