44604-7

Kappa light chains.free [Presence] in Urine by Immunofixation

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Part Descriptions

LP29081-4 Immunoglobulin light chains.kappa.free
Healthy patients have the majority of light chains in serum bound to heavy chains. Low levels of free light chains (unbound) are normal due to the over-production and secretion of free light chains by plasma cells. In the kidneys, the free light chains are selectively reabsorbed by the tubular cells, so their presence in urine is likely due to secretion into the urinary tract. Elevation of monoclonal free light chains in serum or urine signal malignant plasma cell proliferation (multiple myeloma), primary amyloidosis, or light chain deposition disease. Elevation of polyclonal free light chains suggests autoimmune diseases such as systemic lupus erythematosus. (Information from Freelite Beckman Coulter IMMAGE II package insert, Version 23, Feb 2009) Source: Regenstrief Institute

LP6336-4 Immunofixation
Plasma or concentrated urine is deposited on a gel. With an electrical current the proteins are sorted in function of their size, after which antigens for each targeted type of immunoglobulin are deposited on the gel. Thus more or less narrow bands appear on the gel, marking the location of the various immunoglobulines.
Immunofixation tends to replace protein electrophoresis because:

• it is faster (results within three hours);
• it is somewhat more sensitive. Immunofixation may reveal an immunoglobulin missed out by protein electrophoresis, especially at low concentrations (less than 1 gram/litre);
• it can be partially automated and can be used in more laboratories;
• it is more easily read and interpreted.

Immunofixation is however only sensitive to immunoglobulins and is more expensive than protein electrophoresis. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Immunofixation

Fully-Specified Name

Component: Immunoglobulin light chains.kappa.free
Property: PrThr
Time: Pt
System: Urine
Scale: Ord
Method: Immunofixation

Additional Names

Long Common Name: Kappa light chains.free [Presence] in Urine by Immunofixation
Short Name: Kappa LC Free Ur Ql IFE
Display Name: Immunoglobulin light chains.kappa.free Immunofixation Ql (U)
Consumer Name Alpha Get Info: Free kappa light chains, Urine

Basic Attributes

Class: CHEM
Type: Laboratory
First Released: Version 2.17
Last Updated: Version 2.63
Change Reason: The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016. Changed the LCN from 'Immunoglobulin light chains.kappa.free' to ' Kappa light chains.free' for readability.
Order vs. Observation: Observation

Member of these Groups Get Info

LOINC Group	Group Name
LG16698-9	Immunoglobulin light chains.kappa.free\|PrThr\|Pt\|ANYUrine
LG36221-6	Immunoglobulin light chains.kappa.free\|PrThr\|Urine

Language Variants Get Info

Tag	Language	Translation
es-ES	Spanish (Spain)	Cadenas ligeras kappa libres:PrThr:Punto temporal:Orina:Ord:Inmunofijación
es-MX	Spanish (Mexico)	Cadenas ligeras de inmunoglobulina kappa.libre:Presencia o umbral:Punto temporal:Orina:Ordinal:Inmunofijación
et-EE	Estonian (Estonia)	Immuunglobuliinide kerged kapaahelad:PrThr:Pt:U:Ord:Immuunfiksatsioon Synonyms: Immuunglobuliinide kerged kapaahelad Järgarvuline Juhuslik Uriin
fr-CA	French (Canada)	Chaîne légère des immunoglobulines.kappa.libre:Présence-Seuil:Temps ponctuel:Urine:Ordinal:Immunofixation
fr-FR	French (France)	Immunoglobuline chaines légères libres kappa:Présence/Seuil:Ponctuel:Urine:Qualitatif:Immunofixation
fr-BE	French (Belgium)	Chaîne légère des immunoglobulines.kappa.libre:PrThr:Temps ponctuel:Urine:Ordinal:Immunofixation Synonyms: FLC.kappa.libre, FLC.kappa LC LC. Kappa
it-IT	Italian (Italy)	Immunoglobuline, catene leggere.kappa.libere:PrThr:Pt:Urine:Ord:Immunofissazione Synonyms: Catene leggere delle immunoglobuline Catene leggere kappa delle immunoglobuline Catene leggere kappa libere delle immunoglobuline Chimica Presenza o Soglia Punto nel tempo (episodio)
nl-NL	Dutch (Netherlands)	immunoglobuline lichte ketens.kappa.vrij:aanwezigheid:moment:urine:ordinaal:immunofixatie
pl-PL	Polish (Poland)	Łańcuchy lekkie immunoglobulin.kappa.wolne:granica wykrywalności:punkt w czasie:mocz:półilościowy:immunofiksacja Synonyms: Łańcuchy lekkie immunoglobulin Łańcuchy lekkie kappa immunoglobuliny Łańcuchy lekkie wolne kappa
pt-BR	Portuguese (Brazil)	Imunoglobulinas cadeias leves.kappa.livre:ACnc:Pt:Urina:Ord:Imunofixação Synonyms: ; Kappa LC Free; BJ Protein; BJP; Bence Jones protein; Arbitrary concentration; Point in time; Random; Ur; UR; Urn; UA; Ql; Ordinal; QL; Qualitative; Qual; Screen; IFE; Ifix; Immunofixation electrophoresis; Immune globulin; Imunoglbon; Immuno; Imunoglobn; Immunoglobin; Immunoglob; FR; Non-protein bound; Chain; Chemistry
ru-RU	Russian (Russian Federation)	Иммуноглобулин легкие цепи.каппа.свободные:PrThr:ТчкВрм:Моча:Пор:Иммунофиксация Synonyms: Порядковый Точка во времени;Момент
tr-TR	Turkish (Turkey)	İmmünglobulin hafif zincirler.kappa.serb:MevcEşik:Zmlı:İdrar:Srl:İmmünfiksasyon Synonyms: Mevcut
zh-CN	Chinese (China)	免疫球蛋白轻链.Kappa 型.游离型:存在情况或阈值:时间点:尿液:序数型:免疫固定电泳分析法 Synonyms: Bence Jones 氏蛋白;Bence Jones 蛋白;BJ 蛋白;B-J 蛋白;BJP;本周氏蛋白;本-周氏蛋白;本周氏蛋白（Bence Jones protein，BJ Protein，BJP）;本周蛋白;本-周蛋白 IFE;Ifix;免疫固定法;免疫固定电泳（Immunofixation electrophoresis，IFE）;免疫固定电泳法 Ig Kappa LC;Kappa 型免疫球蛋白轻链;Kappa 型轻链;Kappa 轻链;κ型免疫球蛋白轻链;κ型轻链;κ轻链;免疫球蛋白轻链.Kappa;免疫球蛋白轻链.κ型;轻链.Kappa;轻链.Kappa 型;轻链.κ;轻链.κ型丙种球蛋白依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型免疫球蛋白（Immunoglobulin，Ig）免疫球蛋白类免疫球蛋白轻链.Kappa 型.游离;免疫球蛋白轻链.Kappa.游离;免疫球蛋白轻链.Kappa.游离型;免疫球蛋白轻链.κ型.游离;免疫球蛋白轻链.κ型.游离型;游离 Kappa LC;游离 Kappa 型免疫球蛋白轻链;游离 Kappa 型轻链;游离 Kappa 轻链;游离κ型免疫球蛋白轻链;游离κ型轻链;游离κ轻链;游离型 Kappa LC;游离型 Kappa 免疫球蛋白轻链;游离型 Kappa 型免疫球蛋白轻链;游离型 Kappa 型轻链;游离型 Kappa 轻链;游离型κ免疫球蛋白轻链;游离型化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）尿;小便;下泉时刻;随机;随意;瞬间游离链非蛋白结合型非蛋白质结合型

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Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.