Version 2.78

Part Descriptions

LP18494-2   Activated protein C resistance
A hemostatic disorder characterized by a poor anticoagulant response to activated protein C (APC) which increases the risk of a clotting disorder. The activated form of Factor V (Factor Va) is more slowly degraded by activated protein C. Factor V Leiden mutation (R506Q) is the most common cause of APC resistance. Source: National Library of Medicine, MeSH 2006

LP18494-2   Activated protein C resistance
Activated protein C resistance (APC) has emerged as the most frequent abnormality in patients with idiopathic thrombosis. Patients found to be heterozygous for APC resistence have a seven fold increased risk for venous thrombosis as compared to the general popualtion. Homozygous individuals have an eight fold increased risk of thrombosis. Familial studies and counselling should be considered for positive patients. The activated form of Factor V (Factor Va) is more slowly degraded by activated protein C. Factor V Leiden mutation (R506Q) is the most common cause of APC resistance. Often measured as the ratio of the Appt W APC. Source: Regenstrief Institute

Fully-Specified Name

Component
Activated protein C resistance
Property
Imp
Time
Pt
System
PPP
Scale
Nom
Method

Additional Names

Short Name
aPCR PPP-Imp
Display Name
Activated protein C resistance (PPP) [Interp]
Consumer Name Alpha Get Info
Activated Protein C Resistance, Blood

Basic Attributes

Class
COAG
Type
Laboratory
First Released
Version 2.21
Last Updated
Version 2.73
Order vs. Observation
Observation
Common Test Rank Get Info
16434

Member of these Panels

LOINC Long Common Name
48596-1 Activated protein C resistance panel - Platelet poor plasma

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Resistencia a la proteína C activada:Impresión/interpretación del estudio:Punto temporal:Plasma pobre en plaquetas:Nom:
es-MX Spanish (Mexico) Resistencia a la proteína C activada:Impresión / interpretación del estudio:Punto temporal:Plasma pobre en plaquetas:Nominal:
fr-CA French (Canada) Résistance à la protéine C activée:Impression:Temps ponctuel:Plasma pauvre en plaquettes:Nominal:
fr-FR French (France) Protéine C activée résistance:Interprétation:Ponctuel:Plasma pauvre en plaquettes:Résultat nominal:
fr-BE French (Belgium) Résistance à la protéine C activée:Impression/interprétation d'étude:Temps ponctuel:Plasma pauvre en plaquettes:Nominal:
Synonyms: RPCa
it-IT Italian (Italy) Proteina C attivata, resistenza:Imp:Pt:PPP:Nom:
Synonyms: Impressione/interpretazione di studio Plasma povero di piastrine Punto nel tempo (episodio) Resistenza alla proteina C attivata Studio di coagulazione
nl-NL Dutch (Netherlands) geactiveerd proteïne C-resistentie:interpretatie:moment:plaatjesarm plasma:nominaal:
Synonyms: coagulatiemethode
pt-BR Portuguese (Brazil) Resistência a proteína C ativada:Imp:Pt:PPPQ:Nom:
Synonyms: ; Prot C; PC; Autoprothrombin II-a; PR; aPCR; APCr; APC-R; Interpretation; Interp; Impression; Impressions; Point in time; Random; Platelet poor plasma; Plas; Nominal; Resistanc; Resist; Resistent; Resistant; APC; COAGULATION
ru-RU Russian (Russian Federation) Активированный протеин С резистентность:Впчт:ТчкВрм:ОПП:Ном:
Synonyms: Белок Белок C Впечатление/интерпретация исследования Номинальный;Именной Обеднённая пластинками плазма;Бедная тромбоцитами плазма Точка во времени;Момент
tr-TR Turkish (Turkey) Aktiflenmiş protein C resistans:İzlnm:Zmlı:TFkP:Snf:
zh-CN Chinese (China) 活化蛋白 C 抗性:印象:时间点:贫血小板血浆:名义型:
Synonyms: APC 抗性;APC 抵抗;aPCR;APC-R;活化 C 蛋白抗性;活化蛋白 C 抗性（Activated protein C resistance，APC-R）;活化蛋白 C 抗性是采用 APC 的 aPTT 与不采用 APC 的 aPTT 之比。;活化蛋白 C 抵抗;活化蛋白 C 抵抗性 C 型;丙;丙型 C 蛋白;PC;自体凝血因子 II-a;自体凝血素 II-a;自体凝血酶原 II-a;自体前凝血酶 II-a;自体因子 II-a;自体第二凝血因子-a;自体第二因子-a;自身凝血因子 II-a;自身凝血素 II-a;自身凝血酶原 II-a;自身前凝血酶 II-a;自身因子 II-a;自身第二凝血因子-a;自身第二因子-a;蛋白 C（Protein C，PC）;蛋白质 C PR;Prot;成分 - 化学 - 蛋白质类;蛋白;朊;蛋白质类;蛋白质类物质 乏血小板血浆;Platelet poor plasma;PPP 凝血功能;凝血功能试验;凝血过程;血液凝固;血液凝固功能;血液凝固过程 分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答 印象是一种诊断陈述，始终是对其他某种观察指标的解释或抽象（一系列检验项目结果、一幅图像或者整个某位病人），而且几乎总是由某位专业人员产生。;检查印象;检查印象/解释;检查的印象/解释;检查解释;解释;阐释 抗力 抗耐性 抵抗力 抵抗性 时刻;随机;随意;瞬间 活化型蛋白C（Activated protein C，APC） 激活型蛋白C 激活型蛋白C（Activated protein C，APC） 电阻 耐性 阻力

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