49308-0
Neutrophil cytoplasmic Ab pattern [Interpretation] in Serum by Immunofluorescence Narrative
Active
Part Description
LP16728-5 Neutrophil cytoplasmic
Neutrophil cytoplasmic antibodies are autoantibodies that bind to the granulocytes of neutrophils. These antibodies were first identified in patients with Wegener's granulomatosis (WG) who also had systemic vasculitis and necrotizing crescentic glomerulonephritis. When viewed under a fluorescent microscope, a typical cytoplasmic fluorescent pattern is visible. These ANCA are called cytoplasmic ANCA (c-ANCA) and the antigen they target is proteinase 3 (PR3) which is part of the azurophilic granules of neutrophils. The perinuclear ANCA (p-ANCA) targets the antigen myeloperoxidase (MPO) and is associated with idiopathic forms of systemic vasculitis and glomerulonephritis. A third ANCA antibody is the atypical ANCA (a-ANCA). The presence of a-ANCA has been found in patients with inflammatory bowel diseases including ulcerative colitis (UC) and Crohn's disease (CD), autoimmune-mediated liver diseases, rheumatoid arthritis RA, and systemic lupus erythematosus (SLE). PMID: 27366026
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Neutrophil cytoplasmic Ab pattern
- Property
- Imp
- Time
- Pt
- System
- Ser
- Scale
- Nar
- Method
- IF
Additional Names
- Short Name
- ANCA Ab pattern Ser IF-Imp
- Display Name
- Neutrophil cytoplasmic Ab pattern IF Nar (S) [Interp]
- Consumer Name Alpha Get Info
- Interpretation of Neutrophil cytoplasmic Ab pattern test result, Blood
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.21
- Last Updated
- Version 2.73
- Order vs. Observation
- Observation
- Common Test Rank Get Info
- 18909
Member of these Groups Get Info
LOINC Group | Group Name |
---|---|
LG7000-5 | Neutrophil cytoplasmic Ab pattern| |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
de-DE | German (Germany) | Neutrophiler zytoplasmatischer Ak-Muster: |
es-ES | Spanish (Spain) | Citoplasma de neutrófilo Patrón de anticuerpos: |
es-MX | Spanish (Mexico) | Patrón de Ab citoplasmático de neutrófilos: |
fr-CA | French (Canada) | Neutrophile cytoplasmique, Patron des Ac: |
fr-FR | French (France) | Cytoplasme des polynucléaires neutrophiles anticorps aspect: |
fr-BE | French (Belgium) | Neutrophile cytoplasmique Anticorps.Profil des Ac: Synonyms: Anticorps |
it-IT | Italian (Italy) | Neutrofilo citoplasmico profilo Ab: Synonyms: anticorpo Immunofluorescenza (IF) Impressione/interpretazione di studio profilo anticorpo Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant |
nl-NL | Dutch (Netherlands) | neutrofiel cytoplasmatisch As-patroon: Synonyms: antistof; |
pt-BR | Portuguese (Brazil) | Citoplasma dos Neutrófilos Ac padrão: Synonyms: ANCA; |
ru-RU | Russian (Russian Federation) | Нейтрофилов цитоплазматический Ат паттерн: Synonyms: Антитело Впечатление/интерпретация исследования Иммунофлюоресценция (ИФ) Описательный Сыворотка Точка во времени; |
tr-TR | Turkish (Turkey) | Nötrofil sitoplazmik Ab yapısı: Synonyms: Ak Ak yapısı İmmünflorerans |
zh-CN | Chinese (China) | 嗜中性粒细胞细胞浆 抗体模式: Synonyms: Ab; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=49308-0
LOINC Copyright
Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright