49575-4
Sphingomyelin/Surfactant.total in Amniotic fluid
Active
Part Description
LP15698-1 Sphingomyelin
Sphingomyelin (SPH) is a type of sphingolipid found in animal cell membranes, especially in the membranous myelin sheath that surrounds some nerve cell axons. It usually consists of phosphorylcholine and ceramide. In humans SPH represents ~85% of all sphingolipids.
Sphingomyelin can accumulate in a rare hereditary disease called Niemann-Pick Disease, types A and B. It is a genetically-inherited disease caused by a deficiency in the enzyme Sphingomyelinase, which causes the accumulation of Sphingomyelin in spleen, liver, lungs, bone marrow, and the brain, causing irreversible neurological damage. Of the two types involving Sphingomyelinase, type A occurs in infants. It is characterized by jaundice, an enlarged liver, and profound brain damage. Children with this type rarely live beyond 18 months. Type B involves an enlarged liver and spleen, which usually occurs in the pre-teen years. The brain is not affected. Most patients present with <1% normal levels of the enzyme in comparison to normal levels.
An excess of spingomyelin in the red blood cell membrane (as in abetalipoproteinemia) causes excess lipid accumulation in the outer leaflet of the red blood cell plasma membrane. This results in abnormally shaped red cells called acanthocytes.
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Source: Wikipedia
, Wikipedia
Fully-Specified Name
- Component
- Sphingomyelin/Surfactant.total
- Property
- MFr
- Time
- Pt
- System
- Amnio fld
- Scale
- Qn
- Method
Additional Names
- Long Common Name
- Sphingomyelin/Surfactant.total in Amniotic fluid
- Short Name
- Sphingomyelin MFr Amn
- Display Name
- Sphingomyelin/Total surfactant (Amn fld) [Mass fraction]
- Consumer Name Alpha Get Info
- Sphingomyelin/Surfactant.total, Amniotic fluid
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.22
- Last Updated
- Version 2.70 (MIN)
- Order vs. Observation
- Both
Member of these Panels
LOINC | Long Common Name |
---|---|
50009-0 | Fetal lung maturity panel - Amniotic fluid |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
el-GR | Greek (Greece) | Σφιγγομυελινάση/Επιφανειοδραστική ουσία.ολική: Synonyms: MFr Επιφανειοδραστική ουσία Σφιγγομυελινάση |
es-ES | Spanish (Spain) | Esfingomielina/Surfactante.total: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | Esfingomielina / Surfactante total: |
et-EE | Estonian (Estonia) | Sfingomüeliin/surfaktant.üld: Synonyms: Amnionivedelik Juhuslik Kvantitatiivne Pindaktiivne aine |
fr-CA | French (Canada) | Sphingomyéline/Surfactant.total: |
fr-FR | French (France) | Sphingomyéline/surfactant total: |
fr-BE | French (Belgium) | Sphingomyéline/Surfactant.total: |
it-IT | Italian (Italy) | Sfingomielina/Surfattante totale: Synonyms: Chimica Frazione di massa Liquido amniotico Punto nel tempo (episodio) Tensioattivo |
nl-NL | Dutch (Netherlands) | sfingomyeline/surfactant.totaal: |
pt-BR | Portuguese (Brazil) | Esfingomielina/Surfactante.total: Synonyms: Mass fraction; |
ru-RU | Russian (Russian Federation) | Сфингомиелин/Сурфактант.общий: Synonyms: Амниотическая жидкость Количественный Массовая доля Точка во времени; |
tr-TR | Turkish (Turkey) | Sfingomiyelin/Sürfaktan.total: Synonyms: Amniyon mayii |
zh-CN | Chinese (China) | 神经鞘磷脂/表面活性物质.总计: Synonyms: MFr 全体数量 全部 共计 化学; |
Example Units
Unit | Source |
---|---|
% | Example UCUM Units |
% | REGENSTRIEF |
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