Version 2.78

Part Descriptions

LP14377-3   Aldosterone
Aldosterone is a steroid hormone produced by the outer-section (zona glomerulosa) of the adrenal cortex in the adrenal gland to regulate sodium and potassium balance in the blood. It is synthesized from cholesterol by aldosterone synthase, which is absent in other sections of the adrenal gland. It is the sole endogenous member of the class of mineralocorticoids. Acting on mineralocorticoid receptors (MR) on principal cells in the collecting ducts of the kidneys, it increases the permeability of their apical (luminal) membrane to potassium and sodium and activates their basolateral Na+K+ pumps, stimulating ATP hydrolysis, reabsorbing sodium (Na+) ions and water into the blood, and excreting potassium (K+) ions into the urine. Aldosterone also stimulates H+ secretion by intercalated cells in the collecting duct, regulating plasma bicarbonate (HCO3-) levels and its acidbase balance. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Aldosterone (Wikipedia)

LP14377-3   Aldosterone
Used to detect hyper and hypo aldosteronisnm. Hypoaldosteronism can occur in any condition that causes destruction or dysfunction of the adrenal gland.1,2,4 Hypoaldosterism can be due to primary adrenal insufficiency , congenital adrenal hypoplasia, acquired secondary aldosterone deficiency (hyporeninemic hypoaldosteronism), and acquired Hyporeninemic hypoaldosteronism is the most common form of isolated hypoaldosteronism and is results from impaired renin release from the kidney. Congenital hypoaldosteronism caused by inherited enzymatic defects in aldosterone biosynthesis are rare. Corticosterone methyloxidase I (CMO I) deficiency is associated with elevated serum levels of corticosterone and low levels of 18-hydroxy-corticosterone and aldosterone. Corticosterone methyloxidase II (CMO II) deficiency produces high levels of 18-hydroxy-corticosterone, the immediate precursor of aldosterone.
Acquired primary hypoaldosteronism can be caused by the administration of heparin. Also, persistently hypotensive, critically ill patients with sepsis, pneumonia, peritonitis, cholangitis, and liver failure can have inappropriately low plasma aldosterone concentrations in relation to elevated plasma renin activity. Primary hyperaldosteronism, also referred to as Conn syndrome, is due to overproduction of aldosterone by one or both of the adrenal glands. Some recent studies suggest that 10% to 15% of Hyper thyroidism cases are due to (or associated with ) primary hyperaldosteronism. Secondary hyperaldosteronism is relatively common and can occur as the result of any condition that decreases blood flow to the kidneys (ie, renal artery stenosis), decreases blood pressure, or lowers plasma sodium levels. Secondary hyperaldosteronism may also be seen with cirrhosis, congestive heart failure. and toxemia of pregnancy. Several studies have suggested that high-normal aldosterone levels predict development of high blood pressure in normotensive subjects and that increased aldosterone action contributes to hypertension, cardiovascular fibrosis, and cardiac hypertrophy. Source: Regenstrief Institute

Fully-Specified Name

Component
Aldosterone^1H post 250 ug corticotropin IM
Property
SCnc
Time
Pt
System
Ser/Plas
Scale
Qn
Method

Additional Names

Short Name
Aldost 1h p 250 ug ACTH IM SerPl-sCnc
Display Name
Aldosterone 1 Hr post 250 ug corticotropin IM [Moles/Vol]
Consumer Name Alpha Get Info
Aldosterone 1 hr after 250 ug Corticotropin intramuscular, Blood

Basic Attributes

Class
CHAL
Type
Laboratory
First Released
Version 2.22
Last Updated
Version 2.70
Order vs. Observation
Observation

Member of these Groups Get Info

LOINC Group Group Name
LG50482-5 Aldosterone^1H post 250 ug corticotropin IM|Pt|Ser/Plas

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Aldosterona^1 hora pos 250 ug corticotropina IM:Concentración de sustancia:Punto temporal:Suero o Plasma:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Aldosterona ^1H después de 250 ug de corticotropina IM:Concentración de sustancias:Punto temporal:Suero o Plasma:Cuantitativo:
fr-CA French (Canada) Aldostérone^1 h post 250 ug hormone adrénocorticotrope IM:Concentration de substance:Temps ponctuel:Sérum/Plasma:Quantitatif:
fr-FR French (France) Aldostérone T01h après synacthène (250µg,IM):Moles/Volume:Ponctuel:Sérum/Plasma:Numérique:
fr-BE French (Belgium) Aldostérone^1 h post 250 ug hormone adrénocorticotrope IM:Concentration de substance:Temps ponctuel:Sérum/Plasma:Quantitatif:
Synonyms: 1h après ACTH 250µg ACTH après 1h. ACTH IM 250µg
it-IT Italian (Italy) Aldosterone^1h post 250 ug corticotropina IM:SCnc:Pt:Siero/Plasma:Qn:
Synonyms: 1 ora dopo 250 ug di corticotropina 1 ora dopo 250 ug di corticotropina IM Concentrazione di Sostanza Plasma Punto nel tempo (episodio) Siero Siero o Plasma Test di provocazione
nl-NL Dutch (Netherlands) aldosteron^60 min na 250 ug ACTH IM:mol/volume:moment:serum of plasma:kwantitatief:
Synonyms: 1 uur na 250 ug ACTH 1 uur na 250 ug ACTH IM adrenocorticotroop hormoon; adrenocorticotrofine; corticotrofine
pt-BR Portuguese (Brazil) Aldosterona^60 min após 250 ug de corticotrofina IM:SCnc:Pt:Sor/Plas:Qn:
Synonyms: ; ACTH; Rc206; c74; Cortrosyn; c206; Adrenocorticotropin; Adrenocorticotrophic hormone; Aldost; 1H p 250 ug ACTH IM; Substance concentration; Level; Point in time; Random; SerPl; SerPlas; SerP; Serum; SR; Plasma; Pl; Plsm; Quantitative; QNT; Quant; Quan; mcg; PST; After; CHEMISTRY.CHALLENGE TESTING; CHEMISTRY.CHALLENGE TESTING
ru-RU Russian (Russian Federation) Альдостерон^1 час после 250 мкг кортикотропина внутримышечно:МолКонц:ТчкВрм:Сыв/Плаз:Колич:
Synonyms: Количественный Молярность;Молярная объёмная концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR Turkish (Turkey) Aldosteron^1Sa snr 250 ug IM kortikotropin:SubKons:Zmlı:Ser/Plaz:Kant:
zh-CN Chinese (China) 醛固酮^在肌肉注射250 ug促肾上腺皮质激素之后1小时:物质的量浓度:时间点:血清/血浆:定量型:
Synonyms: 1Hr之后于250 ug 促肾上腺皮质激素 IM;1小时之后于肌肉注射250 ug促肾上腺皮质激素;1小时之后于肌肉注射250微克促肾上腺皮质激素;60Min之后于250 ug 促肾上腺皮质激素 IM;60分钟之后于肌肉注射250 ug促肾上腺皮质激素;60分钟之后于肌肉注射250微克促肾上腺皮质激素;在250 ug 促肾上腺皮质激素 IM之后1Hr;在250 ug 促肾上腺皮质激素 IM之后60Min;在肌肉注射250 ug促肾上腺皮质激素之后60分钟;在肌肉注射250微克促肾上腺皮质激素之后1小时;在 1Hr之后于给予250 ug促肾上腺皮质激素;1Hr之后于给予250微克促肾上腺皮质激素;1小时之后于给予250 ug促肾上腺皮质激素;1小时之后于给予250微克促肾上腺皮质激素;60Min之后于给予250 ug促肾上腺皮质激素;60Min之后于给予250微克促肾上腺皮质激素;60分钟之后于给予250 ug促肾上腺皮质激素;60分钟之后于给予250微克促肾上腺皮质激素;在给予250 ug促肾上腺皮质激素之后1Hr;在给予250 ug促肾上腺皮质激素之后60Min;在给予250 ug促肾上腺皮质激素之后60 ACTH ACTH;亲皮质素;促皮质素 ug XXX刺激 - 在...之后 μg 之后于... 克分子浓度;克分子浓度(单位体积);摩尔浓度;摩尔浓度(单位体积);物质的量浓度(单位体积) 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 在...以后 在后 时刻;随机;随意;瞬间 血清或血浆 醛基甾酮;醛甾酮;醛皮质酮;醛类脂醇

Example Units

Unit Source
pmol/L Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=50173-4