50367-2

Propionylglycine/Creatinine [Molar ratio] in 24 hour Urine

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Part Descriptions

LP14518-2   Propionylglycine
Propionylglycine is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. However, the excretion of certain acyl glycines is increased in several inborn errors of metabolism. In certain cases the measurement of these metabolites in body fluids can be used to diagnose disorders associated with mitochondrial fatty acid beta-oxidation. Acyl glycines are produced through the action of glycine N-acyltransferase (EC 2.3.1.13) which is an enzyme that catalyzes the chemical reaction: acyl-CoA + glycine < -- > CoA + N-acylglycine The level of propionylglycine is elevated in patients with propionic acidemia, which is an inherited deficiency of propionyl-CoA carboxylase. (Disorders of propionate and methylmalonate metabolism. In The Metabolic and Molecular Bases of Inherited Disease). Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, Propionylglycine

LP32035-5   Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas. Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, Creatinine

Fully-Specified Name

Component

Propionylglycine/Creatinine

Property

SRto

Time

24H

System

Urine

Scale

Qn

Method

Additional Names

Short Name

Propionylgly/Creat 24h Ur-sRto

Display Name

Propionylglycine/Creatinine (24H U) [Molar ratio]

Consumer Name Alpha Get Info

Propionylglycine/Creatinine, Urine

Basic Attributes

Class

CHEM

Type

Laboratory

First Released

Version 2.22

Last Updated

Version 2.70

Order vs. Observation

Both

Member of these Groups Get Info

Language Variants Get Info

Related Names

• 1 day
• 24 hours
• 24HR
• Chemistry
• CR
• Crea
• Creat
• QNT
• Quan
• Quant
• Quantitative
• Scrto
• Substance concentration ratio
• Substance ratio
• UA
• UCr
• UR
• Urn

Example Units

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