53156-6

Methionine/Phenylalanine [Molar ratio] in DBS

Active

Term Description

Methionine/Phenylalanine is a primary marker for Homocystinuria, Hypermethioninemia, Methylene tetrahydrofolate reductase deficiency, Methylcobalamin deficiency and Homocystinuria-megaloblastic anemia. Secondary marker for Methylmalonic aciduria and homocystinuria.
Source: Regenstrief LOINC

Part Descriptions

LP15730-2   Methionine
Methionine is an essential nonpolar amino acid, and a lipotropic. Methionine and cysteine are the only sulfur-containing proteinogenic amino acids. The methionine derivative S-adenosyl methionine (SAM) serves as a methyl donor. Methionine plays a role in cysteine, carnitine and taurine synthesis by the transsulfuration pathway, lecithin production, the synthesis of phosphatidylcholine and other phospholipids. Improper conversion of methionine can lead to atherosclerosis. Methionine, a chelating agent, is one of only two amino acids encoded by a single codon (AUG) in the standard genetic code (tryptophan, encoded by UGG, is the other). The codon AUG is also significant, in that it carries the Start message for a ribosome to begin protein translation from mRNA. As a consequence, methionine is incorporated into the N-terminal position of all proteins in eukaryotes and archaea during translation, although it is usually removed by post-translational modification. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Methionine (Wikipedia)

LP70160-4   Phenylalanine
Phenylalanine is an essential alpha-amino acid. It exists in two forms, a D and an L form, which are enantiomers (mirror-image molecules) of each other. It has a benzyl side chain and its name comes from its chemical structures that consists of a phenyl group substituted for one of the hydrogens in the side chain of alanine. Because of its phenyl group, phenylalanine is an aromatic compound that at room temperature exists as a white, powdery solid. L -phenylalanine (LPA) is an electrically-neutral amino acid and its enantiomer, D -phenylalanine (DPA), can be synthesized artificially. L -phenylalanine can also be converted into L -tyrosine, another one of the twenty protein-forming amino acids. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Phenylalanine (Wikipedia)

Fully-Specified Name

Component

Methionine/Phenylalanine

Property

SRto

Time

Pt

System

Bld.dot

Scale

Qn

Method

Additional Names

Long Common Name

Methionine/Phenylalanine [Molar ratio] in DBS

Short Name

Methionine/Phe DBS-sRto

Display Name

Methionine/Phenylalanine (DBS) [Molar ratio]

Consumer Name Alpha Get Info

Methionine/Phenylalanine, Dried blood spot

Basic Attributes

Class

CHEM

Type

Laboratory

First Released

Version 2.24

Last Updated

Version 2.73

Order vs. Observation

Both

Member of these Panels

Language Variants Get Info

Related Names

• Blood
• Chemistry
• DBS
• Dried blood spot
• Filter paper
• FP
• Met
• Phe
• PKU
• Point in time
• PPA
• QNT
• Quan
• Quant
• Quantitative
• Random
• Scrto
• Substance concentration ratio
• Substance ratio
• WB
• Whole blood

Example Units

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CodeSystem lookup

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=53156-6

LOINC Copyright

Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.