54058-3
HEDIS 2009-2013 Codes to identify anticonvulsant serum concentration monitoring tests - Valproate (MPM-E)
Discouraged
4086-5 Valproate [Mass/volume] in Serum or Plasma
Part Descriptions
LP16305-2 Valproate
Valproic acid is a compound used as an anticonvulsant and mood-stabilizing drug, primarily in the treatment of epilepsy and bipolar disorder. It is also used to treat migraine headaches and schizophrenia. In epileptics, valproic acid is used to control absence seizures, tonic-clonic seizures (grand mal), complex partial seizures, juvenile myoclonic epilepsy and the seizures associated with Lennox-Gastaut syndrome. It is also used in treatment of myoclonus. In some countries, parenteral (administered intravenously) preparations of valproate are used also as second-line treatment of status epilepticus, alternatively to phenytoin. Related drugs include sodium valproate, used as an anticonvulsant, and a combined formulation, valproate semi-sodium, used as a mood stabilizer and anticonvulsant.
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia
, Valproate (Wikipedia)
LP16305-2 Valproate
Valproic acid is an anticonvulsant that is used alone or with other medication to treat certain types of seizures, mania in people with bipolar disorder, and to prevent migranes before they occur. it cannot be used to treat migranes once they begin.
Valproic acid can also be used for children with attention deficit hyperactivity disorder to treat outbursts of aggression or impaired intellectual functioning, developmental delays, and behavioral disturbances associated with Lennoz-Gastaut syndrome.[MedlinePlus Drug:a682412][NINDS:Disorders/All-Disorders/Lennox-Gastaut-Syndrome-Information-Page]
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Valproate
- Property
- MCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 1.0
- Last Updated
- Version 2.73 (MIN)
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 595
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 54037-7 | HEDIS 2009 panel |
| 57820-3 | HEDIS 2010 panel |
| 60442-1 | HEDIS 2011 panel |
| 67767-4 | HEDIS 2012 panel |
| 72199-3 | HEDIS 2013 panel |
| 74234-6 | HEDIS 2014 Value Sets |
| 55427-9 | Seizure disorder tracking panel |
| 57775-9 | Valproate.free and Valproate panel - Serum or Plasma |
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG49789-7 | Valproate| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-AT | German (Austria) | Synonyms: Valproinsäure |
| de-DE | German (Germany) | Valproat: Synonyms: Valproinsäure |
| el-GR | Greek (Greece) | Βαλπροϊκό οξύ: Synonyms: MCnc Βαλπροϊκό οξύ |
| es-AR | Spanish (Argentina) | valproato: |
| es-ES | Spanish (Spain) | Valproato: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Valproato: |
| et-EE | Estonian (Estonia) | Valproaat: Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma |
| fr-CA | French (Canada) | Valproate: |
| fr-FR | French (France) | Valproate: |
| fr-BE | French (Belgium) | Valproate: |
| it-IT | Italian (Italy) | Valproato: Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
| ko-KR | Korean (Korea, Republic Of) | 벨프로에이트: |
| nl-NL | Dutch (Netherlands) | valproaat: |
| pt-BR | Portuguese (Brazil) | Valproato: Synonyms: Valproic acid; |
| ru-RU | Russian (Russian Federation) | Вальпроат: Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени; |
| tr-TR | Turkish (Turkey) | Valproat: |
| zh-CN | Chinese (China) | 2-丙基戊酸: Synonyms: 2-丙基戊酸钠; |
Example Units
| Unit | Source |
|---|---|
| ug/mL | Example UCUM Units |
| mcg/mL | REGENSTRIEF |
4087-3 Valproate Free [Mass/volume] in Serum or Plasma
Part Descriptions
LP207910-3 free DRUG/TOX
The measurement of free (unbound) drug concentrations in plasma is important for certain drugs and has two advantages over measurement of total concentration: (1) the free concentration is independent of changes in plasma binding (e.g., due to changes in albumin), and (2) the free concentration is more directly related to both the efficacy and toxicity of the drug PMID: 6636249. For most drugs and the majority of patients, measuring the free and total concentrations is not necessary. However, for certain drugs, including some anticonvulsants and antibiotics, and specific patient populations, such as critically ill or immunosuppressed patients, the free concentration is a better indicator of therapeutic effect and potential toxicity.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Valproate.free
- Property
- MCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 1.0
- Last Updated
- Version 2.73 (MIN)
- Change Reason
- Order_Obs: changed from 'observation' to 'both' to reflect that the LOINC code can also be used as an order code.
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 1810
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 54037-7 | HEDIS 2009 panel |
| 57820-3 | HEDIS 2010 panel |
| 60442-1 | HEDIS 2011 panel |
| 67767-4 | HEDIS 2012 panel |
| 72199-3 | HEDIS 2013 panel |
| 74234-6 | HEDIS 2014 Value Sets |
| 57775-9 | Valproate.free and Valproate panel - Serum or Plasma |
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG47174-4 | Valproate.free| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| el-GR | Greek (Greece) | Βαλπροϊκό.ελεύθερο: Synonyms: MCnc Βαλπροϊκό οξύ Βαλπροϊκό.ελεύθερο |
| es-AR | Spanish (Argentina) | valproato.libre: |
| es-ES | Spanish (Spain) | Valproico libre: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Valproato.libre: |
| et-EE | Estonian (Estonia) | Valproaat.vaba: Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma |
| fr-CA | French (Canada) | Valproate.libre: |
| fr-FR | French (France) | Valproate libre: |
| fr-BE | French (Belgium) | Valproate.libre: |
| it-IT | Italian (Italy) | Valproato.libero: Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma Valproato Libero |
| ko-KR | Korean (Korea, Republic Of) | 유리벨프로에이트: |
| nl-NL | Dutch (Netherlands) | valproaat.vrije: |
| pt-BR | Portuguese (Brazil) | Valproato.livre: Synonyms: Valproic acid; |
| ru-RU | Russian (Russian Federation) | Вальпроат.свободный: Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени; |
| tr-TR | Turkish (Turkey) | Valproat.serb: |
| zh-CN | Chinese (China) | 2-丙基戊酸.游离型: Synonyms: 2-丙基戊酸.游离; |
Example Units
| Unit | Source |
|---|---|
| ug/mL | Example UCUM Units |
| mcg/mL | REGENSTRIEF |
4088-1 Valproate [Mass/volume] in Serum or Plasma --trough
Part Descriptions
LP16305-2 Valproate
Valproic acid is a compound used as an anticonvulsant and mood-stabilizing drug, primarily in the treatment of epilepsy and bipolar disorder. It is also used to treat migraine headaches and schizophrenia. In epileptics, valproic acid is used to control absence seizures, tonic-clonic seizures (grand mal), complex partial seizures, juvenile myoclonic epilepsy and the seizures associated with Lennox-Gastaut syndrome. It is also used in treatment of myoclonus. In some countries, parenteral (administered intravenously) preparations of valproate are used also as second-line treatment of status epilepticus, alternatively to phenytoin. Related drugs include sodium valproate, used as an anticonvulsant, and a combined formulation, valproate semi-sodium, used as a mood stabilizer and anticonvulsant.
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia
, Valproate (Wikipedia)
LP16305-2 Valproate
Valproic acid is an anticonvulsant that is used alone or with other medication to treat certain types of seizures, mania in people with bipolar disorder, and to prevent migranes before they occur. it cannot be used to treat migranes once they begin.
Valproic acid can also be used for children with attention deficit hyperactivity disorder to treat outbursts of aggression or impaired intellectual functioning, developmental delays, and behavioral disturbances associated with Lennoz-Gastaut syndrome.[MedlinePlus Drug:a682412][NINDS:Disorders/All-Disorders/Lennox-Gastaut-Syndrome-Information-Page]
Source: Regenstrief LOINC
LP20176-1 trough
In medicine, a trough level is the lowest level that a medicine is present in the body. In a medicine that is administered periodically, the trough level should be measured just before the administration of the next dose in order to avoid overdosing. It should be contrasted with a "peak level", which is the highest level of the medicine in the body, and the "average level", which is the mean level over time. It helps in therapeutic drug monitoring. It is widely used in clinical trials for newer medicines for its therapeutic effectiveness and safety.
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia
, Trough levels for therapeutic drug monitoring
Fully-Specified Name
- Component
- Valproate^trough
- Property
- MCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 1.0
- Last Updated
- Version 2.73 (MIN)
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 16623
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 54037-7 | HEDIS 2009 panel |
| 57820-3 | HEDIS 2010 panel |
| 60442-1 | HEDIS 2011 panel |
| 67767-4 | HEDIS 2012 panel |
| 72199-3 | HEDIS 2013 panel |
| 74234-6 | HEDIS 2014 Value Sets |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-DE | German (Germany) | Valproat^TDM Tal: Synonyms: Valproinsäure |
| el-GR | Greek (Greece) | Βαλπροϊκό οξύ^ελάχιστα επίπεδα: Synonyms: MCnc Βαλπροϊκό οξύ |
| es-AR | Spanish (Argentina) | valproato^concentración mínima [valle]: |
| es-ES | Spanish (Spain) | Valproato^Valle monitorización terapéutica de fármacos: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Valproato ^ comedero: |
| et-EE | Estonian (Estonia) | Valproaat^baas: Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma |
| fr-CA | French (Canada) | Valproate^Creux: |
| fr-FR | French (France) | Valproate taux résiduel: |
| fr-BE | French (Belgium) | Valproate^Creux: Synonyms: Minimum, nadir |
| it-IT | Italian (Italy) | Valproato^valore minimo: Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma valore minimo TDM |
| ko-KR | Korean (Korea, Republic Of) | 벨프로에이트^최저 약물 농도 시간: |
| nl-NL | Dutch (Netherlands) | valproaat^dalspiegel: |
| pt-BR | Portuguese (Brazil) | Valproato^basal: Synonyms: Valproic acid; |
| ru-RU | Russian (Russian Federation) | Вальпроат^остаточная концентрация: Synonyms: Количественный Массовая концентрация минимум концентрации Плазма Сыворотка Сыворотка или Плазма Точка во времени; |
| tr-TR | Turkish (Turkey) | Valproat^en düşük: |
| zh-CN | Chinese (China) | 2-丙基戊酸^波谷: Synonyms: 2-丙基戊酸钠; |
Example Units
| Unit | Source |
|---|---|
| ug/mL | Example UCUM Units |
14946-8 Valproate [Moles/volume] in Serum or Plasma
Part Descriptions
LP16305-2 Valproate
Valproic acid is a compound used as an anticonvulsant and mood-stabilizing drug, primarily in the treatment of epilepsy and bipolar disorder. It is also used to treat migraine headaches and schizophrenia. In epileptics, valproic acid is used to control absence seizures, tonic-clonic seizures (grand mal), complex partial seizures, juvenile myoclonic epilepsy and the seizures associated with Lennox-Gastaut syndrome. It is also used in treatment of myoclonus. In some countries, parenteral (administered intravenously) preparations of valproate are used also as second-line treatment of status epilepticus, alternatively to phenytoin. Related drugs include sodium valproate, used as an anticonvulsant, and a combined formulation, valproate semi-sodium, used as a mood stabilizer and anticonvulsant.
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia
, Valproate (Wikipedia)
LP16305-2 Valproate
Valproic acid is an anticonvulsant that is used alone or with other medication to treat certain types of seizures, mania in people with bipolar disorder, and to prevent migranes before they occur. it cannot be used to treat migranes once they begin.
Valproic acid can also be used for children with attention deficit hyperactivity disorder to treat outbursts of aggression or impaired intellectual functioning, developmental delays, and behavioral disturbances associated with Lennoz-Gastaut syndrome.[MedlinePlus Drug:a682412][NINDS:Disorders/All-Disorders/Lennox-Gastaut-Syndrome-Information-Page]
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Valproate
- Property
- SCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 1.0k
- Last Updated
- Version 2.73 (MIN)
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 11524
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 54037-7 | HEDIS 2009 panel |
| 57820-3 | HEDIS 2010 panel |
| 60442-1 | HEDIS 2011 panel |
| 67767-4 | HEDIS 2012 panel |
| 72199-3 | HEDIS 2013 panel |
| 74234-6 | HEDIS 2014 Value Sets |
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG49789-7 | Valproate| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-DE | German (Germany) | Valproat: Synonyms: Valproinsäure |
| de-AT | German (Austria) | Synonyms: Valproinsäure |
| el-GR | Greek (Greece) | Βαλπροϊκό οξύ: Synonyms: SCnc |
| es-AR | Spanish (Argentina) | valproato: |
| es-ES | Spanish (Spain) | Valproato: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Valproato: |
| et-EE | Estonian (Estonia) | Valproaat: Synonyms: Aine kontsentratsioon Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma |
| fr-CA | French (Canada) | Valproate: |
| fr-FR | French (France) | Valproate: |
| fr-BE | French (Belgium) | Valproate: |
| it-IT | Italian (Italy) | Valproato: Synonyms: Concentrazione di Sostanza Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
| ko-KR | Korean (Korea, Republic Of) | 벨프로에이트: |
| nl-NL | Dutch (Netherlands) | valproaat: |
| pt-BR | Portuguese (Brazil) | Valproato: Synonyms: Valproic acid; |
| ru-RU | Russian (Russian Federation) | Вальпроат: Synonyms: Количественный Молярность; |
| tr-TR | Turkish (Turkey) | Valproat: |
| zh-CN | Chinese (China) | 2-丙基戊酸: Synonyms: 2-丙基戊酸钠; |
Example Units
| Unit | Source |
|---|---|
| umol/L | Example UCUM Units |
| umol/L | eCHN |
18489-5 Valproate.protein bound [Mass/volume] in Serum or Plasma
Fully-Specified Name
- Component
- Valproate.protein bound
- Property
- MCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 1.0l
- Last Updated
- Version 2.73 (MIN)
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 9436
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 54037-7 | HEDIS 2009 panel |
| 57820-3 | HEDIS 2010 panel |
| 60442-1 | HEDIS 2011 panel |
| 67767-4 | HEDIS 2012 panel |
| 72199-3 | HEDIS 2013 panel |
| 74234-6 | HEDIS 2014 Value Sets |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| el-GR | Greek (Greece) | Βαλπροϊκό οξύ.δεσμευμένο με πρωτεΐνες: Synonyms: MCnc |
| es-AR | Spanish (Argentina) | valproato.unido a proteínas: |
| es-ES | Spanish (Spain) | Proteína de unión a Ácido Valproico: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Valproato unido a proteína: |
| et-EE | Estonian (Estonia) | Valproaat.valguga seotud: Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma |
| fr-CA | French (Canada) | Valproate.lié aux protéines: |
| fr-FR | French (France) | Valproate protéine liée: |
| fr-BE | French (Belgium) | Valproate.lié aux protéines: |
| it-IT | Italian (Italy) | Valproato.proteina legato: Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
| ko-KR | Korean (Korea, Republic Of) | 단백 결합 벨프로에이트: |
| nl-NL | Dutch (Netherlands) | valproaat.eiwit gebonden: |
| pt-BR | Portuguese (Brazil) | Valproato.ligado a proteína: Synonyms: ; |
| ru-RU | Russian (Russian Federation) | Вальпроат.протеин связанный: Synonyms: Белок Вальпроат, связанный с белком Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени; |
| tr-TR | Turkish (Turkey) | Valproate.proteine bağlı: |
| zh-CN | Chinese (China) | 2-丙基戊酸.蛋白质结合型: Synonyms: 2-丙基戊酸.蛋白结合型; |
Example Units
| Unit | Source |
|---|---|
| ug/mL | Example UCUM Units |
21590-5 Valproate.bound/Valproate.total in Serum or Plasma
Fully-Specified Name
- Component
- Valproate.bound/Valproate.total
- Property
- MFr
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 1.0m
- Last Updated
- Version 2.73 (MIN)
- Order vs. Observation
- Observation
- Common Test Rank Get Info
- 9471
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 54037-7 | HEDIS 2009 panel |
| 57820-3 | HEDIS 2010 panel |
| 60442-1 | HEDIS 2011 panel |
| 67767-4 | HEDIS 2012 panel |
| 72199-3 | HEDIS 2013 panel |
| 74234-6 | HEDIS 2014 Value Sets |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| el-GR | Greek (Greece) | Βαλπροϊκό οξύ.δεσμευμένη/Βαλπροϊκό οξύ.ολικό: Synonyms: MFr |
| es-AR | Spanish (Argentina) | valproato.unido/valproato.total: |
| es-ES | Spanish (Spain) | Valproato ligado/Valproato total: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Valproato.bound / Valproato.total: |
| et-EE | Estonian (Estonia) | Valproaat.seotud/valproaat.üld: Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma |
| fr-CA | French (Canada) | Valproate.lié/Valproate.totale: |
| fr-FR | French (France) | Valproate lié/valproate total: |
| fr-BE | French (Belgium) | Valproate.lié/Valproate.totale: |
| it-IT | Italian (Italy) | Valproato.legato/Valproato.totale: Synonyms: Frazione di massa Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
| ko-KR | Korean (Korea, Republic Of) | 결합벨프로에이트/총벨프로에이트: |
| nl-NL | Dutch (Netherlands) | valproaat.gebonden/valproaat.totaal: Synonyms: valproinezuur; |
| pt-BR | Portuguese (Brazil) | Valproato.ligado/Valproato.total: Synonyms: ; |
| ru-RU | Russian (Russian Federation) | Вальпроат.связанный/Вальпроат.общий: Synonyms: Количественный Массовая доля Плазма Сыворотка Сыворотка или Плазма Точка во времени; |
| tr-TR | Turkish (Turkey) | Valproate.bağlı/Valproat.total: |
| zh-CN | Chinese (China) | 2-丙基戊酸.结合型/2-丙基戊酸.总计: Synonyms: 2-丙基戊酸.结合; |
Example Units
| Unit | Source |
|---|---|
| % | Example UCUM Units |
32119-0 Valproate Free [Moles/volume] in Serum or Plasma
Part Descriptions
LP207910-3 free DRUG/TOX
The measurement of free (unbound) drug concentrations in plasma is important for certain drugs and has two advantages over measurement of total concentration: (1) the free concentration is independent of changes in plasma binding (e.g., due to changes in albumin), and (2) the free concentration is more directly related to both the efficacy and toxicity of the drug PMID: 6636249. For most drugs and the majority of patients, measuring the free and total concentrations is not necessary. However, for certain drugs, including some anticonvulsants and antibiotics, and specific patient populations, such as critically ill or immunosuppressed patients, the free concentration is a better indicator of therapeutic effect and potential toxicity.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Valproate.free
- Property
- SCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 2.07
- Last Updated
- Version 2.70 (MIN)
- Order vs. Observation
- Observation
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 54037-7 | HEDIS 2009 panel |
| 57820-3 | HEDIS 2010 panel |
| 60442-1 | HEDIS 2011 panel |
| 67767-4 | HEDIS 2012 panel |
| 72199-3 | HEDIS 2013 panel |
| 74234-6 | HEDIS 2014 Value Sets |
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG47174-4 | Valproate.free| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| el-GR | Greek (Greece) | Βαλπροϊκό.ελεύθερο: Synonyms: SCnc Βαλπροϊκό οξύ Βαλπροϊκό.ελεύθερο |
| es-AR | Spanish (Argentina) | valproato.libre: |
| es-ES | Spanish (Spain) | Valproico libre: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Valproato.libre: |
| et-EE | Estonian (Estonia) | Valproaat.vaba: Synonyms: Aine kontsentratsioon Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma |
| fr-CA | French (Canada) | Valproate.libre: |
| fr-FR | French (France) | Valproate libre: |
| fr-BE | French (Belgium) | Valproate.libre: |
| it-IT | Italian (Italy) | Valproato.libero: Synonyms: Concentrazione di Sostanza Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma Valproato Libero |
| ko-KR | Korean (Korea, Republic Of) | 유리벨프로에이트: |
| nl-NL | Dutch (Netherlands) | valproaat.vrije: |
| pt-BR | Portuguese (Brazil) | Valproato.livre: Synonyms: Valproic acid; |
| ru-RU | Russian (Russian Federation) | Вальпроат.свободный: Synonyms: Количественный Молярность; |
| tr-TR | Turkish (Turkey) | Valproat.serb: |
| zh-CN | Chinese (China) | 2-丙基戊酸.游离型: Synonyms: 2-丙基戊酸.游离; |
Example Units
| Unit | Source |
|---|---|
| umol/L | Example UCUM Units |
| umol/L | eCHN |
32283-4 Valproate Free/Valproate.total in Serum or Plasma
Part Descriptions
LP207910-3 free DRUG/TOX
The measurement of free (unbound) drug concentrations in plasma is important for certain drugs and has two advantages over measurement of total concentration: (1) the free concentration is independent of changes in plasma binding (e.g., due to changes in albumin), and (2) the free concentration is more directly related to both the efficacy and toxicity of the drug PMID: 6636249. For most drugs and the majority of patients, measuring the free and total concentrations is not necessary. However, for certain drugs, including some anticonvulsants and antibiotics, and specific patient populations, such as critically ill or immunosuppressed patients, the free concentration is a better indicator of therapeutic effect and potential toxicity.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Valproate.free/Valproate.total
- Property
- MFr
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 2.07
- Last Updated
- Version 2.73 (MIN)
- Order vs. Observation
- Observation
- Common Test Rank Get Info
- 5529
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 54037-7 | HEDIS 2009 panel |
| 57820-3 | HEDIS 2010 panel |
| 60442-1 | HEDIS 2011 panel |
| 67767-4 | HEDIS 2012 panel |
| 72199-3 | HEDIS 2013 panel |
| 74234-6 | HEDIS 2014 Value Sets |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| el-GR | Greek (Greece) | Βαλπροϊκό.ελεύθερο/Βαλπροϊκό οξύ.ολικό: Synonyms: MFr Βαλπροϊκό οξύ Βαλπροϊκό.ελεύθερο |
| es-AR | Spanish (Argentina) | valproato.libre/valproato.total: |
| es-ES | Spanish (Spain) | Valproico libre/Valproato total: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Valproato.libre/Valproato.total: |
| et-EE | Estonian (Estonia) | Valproaat.vaba/valproaat.üld: Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma |
| fr-CA | French (Canada) | Valproate.libre/Valproate.totale: |
| fr-FR | French (France) | Valproate libre/valproate total: |
| fr-BE | French (Belgium) | Valproate.libre/Valproate.totale: |
| it-IT | Italian (Italy) | Valproato.libero/Valproato.totale: Synonyms: Frazione di massa Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma Valproato Libero |
| ko-KR | Korean (Korea, Republic Of) | 유리벨프로에이트/총벨프로에이트: |
| nl-NL | Dutch (Netherlands) | valproaat.vrije/valproaat.totaal: Synonyms: valproinezuur; |
| pt-BR | Portuguese (Brazil) | Valproato.livre/Valproato.total: Synonyms: Valproic acid; |
| ru-RU | Russian (Russian Federation) | Вальпроат.свободный/Вальпроат.общий: Synonyms: Количественный Массовая доля Плазма Сыворотка Сыворотка или Плазма Точка во времени; |
| tr-TR | Turkish (Turkey) | Valproat.serb/Valproat.total: |
| zh-CN | Chinese (China) | 2-丙基戊酸.游离型/2-丙基戊酸.总计: Synonyms: 2-丙基戊酸.游离; |
Example Units
| Unit | Source |
|---|---|
| % | Example UCUM Units |
| % | REGENSTRIEF |