770-8 Neutrophils/Leukocytes in Blood by Automated count

Part Descriptions

LP14267-6   Neutrophils
Neutrophils are the most common form of white blood cells in healthy adults. Neutrophils are approximately 13 micrometers in diameter and have segmented nuclei with 3-5 lobes that are connected by thin strands of chromatin. (Practical Haematology; Barbara J. Bain, Imelda Bates, Mike A. Laffan,S. Mitchell Lewis; Eleventh edition; 2012) Neutrophils function to fight infection by both engulfing microorganisms and secreting lethal enzymes.
(https://www.ncbi.nlm.nih.gov/pubmedhealth/PMHT0022058/) They are produced in the bone marrow and their primary function is to fight infection. Neutrophil numbers increase in the blood in response to acute bacterial infection, inflammation, necrosis or chronic myelogenous leukemia. Neutrophil levels are decreased in the following conditions: aplastic anemia, autoimmune disorder, cancer, chemotherapy, myelodysplastic syndrome and during a negative reaction to drugs. PMID: 24050624 [MedlinePlus Encyclopedia:19864] Source: Regenstrief LOINC

LP157588-7   Leukocytes
Leukocytes or white blood cells (WBCs) are immune cells that fight infection, neoplasms and other inflammatory conditions, and mediate allergic responses. There are five types of WBCs normally present in the circulation that are all derived from a similar stem cell in the bone marrow. The five type of WBCs are divided into two groups based on the presence or absence of granules in the cytoplasm. The granulocytes include the neutrophils, basophils and eosinophils. The non-granulocytes include the lymphocytes and the monocytes. The neutrophils fight infection by ingesting and digesting bacteria. Eosinophils and basophils respond to allergic reactions and are capable of ingesting antigen-antibody complexes. Monocytes phagocytose bacteria and release interferon to stimulate the immune system. Lymphocytes are divided into T-cells and B-cells. T-cell immunity is cellular and involves the activation of phagocytes and B-cell immunity uses antibodies to fight infection. Both elevated and low leukocyte counts can be markers of infection and malignancy, and low leukocyte counts are associated with a variety of primary and secondary immunodeficiencies, depending on the WBC type(s) that are out of range. (Mosby's manual of diagnostic and laboratory tests, Kathleen Deska Pagana; Timothy James Pagana, Elsevier St. Louis, Mo ©2010) Source: Regenstrief LOINC

Reference Information

Observation Required in Panel

Required

Fully-Specified Name

Component

Neutrophils/Leukocytes

Property

NFr

Time

Pt

System

Bld

Scale

Qn

Method

Automated count

Basic Attributes

Class

HEM/BC

Type

Laboratory

First Released

Version 1.0

Last Updated

Version 2.79 (NAM)

Change Reason

Release 2.79: COMPONENT: Triggered by Coll w SCT: This is a specific fraction case where the denominator is percentage or /100. Because the logic is that the percentage piece is captured by Property: NFr (Numeric Fraction), and by Unit: %, therefore, it is redundant to include "100" in the component;

Order vs. Observation

Observation

Common Test Rank Get Info

35

Member of these Panels

Language Variants Get Info

Related Names

• Auto
• Automated detection
• Blood
• Elec
• Elect
• Electr
• HEMATOLOGY/CELL COUNTS
• Leuc
• Leuk
• Leukocyte
• Lkcs
• Neut
• Neutr
• Neutrophil
• Number fraction
• Percent
• PMN
• PNM
• Point in time
• QNT
• Quan
• Quant
• Quantitative
• Random
• WB
• WBC
• WBCs
• White blood cell
• White blood cells
• Whole blood

Example Units

35332-6 Band form neutrophils/Leukocytes in Blood by Automated count

Part Descriptions

LP15070-3   Neutrophils.band form
A band cell (or band neutrophil) is a white blood cell undergoing granulopoiesis. It is derived from a metamyelocyte which eventually will become a mature granulocyte. In contrat to other neutrophils, band neutrophils possess a curved nucleus rather than a lobar one. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia , Wikipedia

LP157588-7   Leukocytes
Leukocytes or white blood cells (WBCs) are immune cells that fight infection, neoplasms and other inflammatory conditions, and mediate allergic responses. There are five types of WBCs normally present in the circulation that are all derived from a similar stem cell in the bone marrow. The five type of WBCs are divided into two groups based on the presence or absence of granules in the cytoplasm. The granulocytes include the neutrophils, basophils and eosinophils. The non-granulocytes include the lymphocytes and the monocytes. The neutrophils fight infection by ingesting and digesting bacteria. Eosinophils and basophils respond to allergic reactions and are capable of ingesting antigen-antibody complexes. Monocytes phagocytose bacteria and release interferon to stimulate the immune system. Lymphocytes are divided into T-cells and B-cells. T-cell immunity is cellular and involves the activation of phagocytes and B-cell immunity uses antibodies to fight infection. Both elevated and low leukocyte counts can be markers of infection and malignancy, and low leukocyte counts are associated with a variety of primary and secondary immunodeficiencies, depending on the WBC type(s) that are out of range. (Mosby's manual of diagnostic and laboratory tests, Kathleen Deska Pagana; Timothy James Pagana, Elsevier St. Louis, Mo ©2010) Source: Regenstrief LOINC

Observation Required in Panel

Conditional

Fully-Specified Name

Component

Neutrophils.band form/Leukocytes

Property

NFr

Time

Pt

System

Bld

Scale

Qn

Method

Automated count

Basic Attributes

Class

HEM/BC

Type

Laboratory

First Released

Version 2.13

Last Updated

Version 2.79 (NAM)

Change Reason

Release 2.79: COMPONENT: Triggered by Coll w SCT: This is a specific fraction case where the denominator is percentage or /100. Because the logic is that the percentage piece is captured by Property: NFr (Numeric Fraction), and by Unit: %, therefore, it is redundant to include "100" in the component;

Order vs. Observation

Observation

Common Test Rank Get Info

409

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Related Names

• Auto
• Automated detection
• Bands
• Blood
• bnd
• Elec
• Elect
• Electr
• HEMATOLOGY/CELL COUNTS
• Leuc
• Leuk
• Leukocyte
• Lkcs
• N-Band
• Neut
• Neutr
• Neutrophil
• Neuts Band
• Number Fraction
• Percent
• PMN
• PNM
• Point in time
• QNT
• Quan
• Quant
• Quantitative
• Random
• WB
• WBC
• WBCs
• White blood cell
• White blood cells
• Whole blood

Example Units

19023-1 Granulocytes/Leukocytes in Blood by Automated count

Part Descriptions

LP157588-7   Leukocytes
Leukocytes or white blood cells (WBCs) are immune cells that fight infection, neoplasms and other inflammatory conditions, and mediate allergic responses. There are five types of WBCs normally present in the circulation that are all derived from a similar stem cell in the bone marrow. The five type of WBCs are divided into two groups based on the presence or absence of granules in the cytoplasm. The granulocytes include the neutrophils, basophils and eosinophils. The non-granulocytes include the lymphocytes and the monocytes. The neutrophils fight infection by ingesting and digesting bacteria. Eosinophils and basophils respond to allergic reactions and are capable of ingesting antigen-antibody complexes. Monocytes phagocytose bacteria and release interferon to stimulate the immune system. Lymphocytes are divided into T-cells and B-cells. T-cell immunity is cellular and involves the activation of phagocytes and B-cell immunity uses antibodies to fight infection. Both elevated and low leukocyte counts can be markers of infection and malignancy, and low leukocyte counts are associated with a variety of primary and secondary immunodeficiencies, depending on the WBC type(s) that are out of range. (Mosby's manual of diagnostic and laboratory tests, Kathleen Deska Pagana; Timothy James Pagana, Elsevier St. Louis, Mo ©2010) Source: Regenstrief LOINC

LP18643-4   Granulocytes
Granulocytes are a category of white blood cells characterised by the presence of granules in their cytoplasm. Mature granulocytes comprise neutrophils, eosinophils and basophils, depending on the staining of the granules. Neutrophils, also called polymorphonuclear leukocytes (PMN or PML) because of the varying shapes of the nucleus, are by far the most abundant granulocytes. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia , Granulocytes (Wikipedia)

Observation Required in Panel

Conditional

Fully-Specified Name

Component

Granulocytes/Leukocytes

Property

NFr

Time

Pt

System

Bld

Scale

Qn

Method

Automated count

Basic Attributes

Class

HEM/BC

Type

Laboratory

First Released

Version 1.0l

Last Updated

Version 2.79 (NAM)

Change Reason

Release 2.79: COMPONENT: Triggered by Coll w SCT: This is a specific fraction case where the denominator is percentage or /100. Because the logic is that the percentage piece is captured by Property: NFr (Numeric Fraction), and by Unit: %, therefore, it is redundant to include "100" in the component;

Order vs. Observation

Observation

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4449

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Related Names

• Auto
• Automated detection
• Blood
• Elec
• Elect
• Electr
• Gran
• Grans
• Granulocyte
• Granulocytes
• HEMATOLOGY/CELL COUNTS
• Leuc
• Leuk
• Leukocyte
• Lkcs
• Number fraction
• Percent
• Point in time
• QNT
• Quan
• Quant
• Quantitative
• Random
• WB
• WBC
• WBCs
• White blood cell
• White blood cells
• Whole blood

Example Units

736-9 Lymphocytes/Leukocytes in Blood by Automated count

Part Descriptions

LP14540-6   Lymphocytes
White blood cells formed in lymphoid tissue. The nucleus is round or ovoid with coarse, irregularly clumped chromatin whereas the cytoplasm is typically pale blue with azurophilic (if any) granules. Most lymphocytes can be classified as either T cells (transit through the thymus), B cells or natural killer cells (NK). Source: National Library of Medicine, MeSH 2006

LP14540-6   Lymphocytes
A lymphocyte is a type of white blood cell in the vertebrate immune system.

A lymphocyte count is usually part of a peripheral complete blood cell count and is expressed as percentage of lymphocytes to total white blood cells counted. A general increase in the number of lymphocytes is known as lymphocytosis whereas a decrease is lymphocytopenia.

An increase in lymphocyte concentration is usually a sign of a viral infection (in some rare case, leukemias are found through an abnormally raised lymphocyte count in an otherwise normal person).

A low normal to low absolute lymphocyte concentration is associated with increased rates of infection after surgery or trauma. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia , Lymphocytes (Wikipedia)

LP157588-7   Leukocytes
Leukocytes or white blood cells (WBCs) are immune cells that fight infection, neoplasms and other inflammatory conditions, and mediate allergic responses. There are five types of WBCs normally present in the circulation that are all derived from a similar stem cell in the bone marrow. The five type of WBCs are divided into two groups based on the presence or absence of granules in the cytoplasm. The granulocytes include the neutrophils, basophils and eosinophils. The non-granulocytes include the lymphocytes and the monocytes. The neutrophils fight infection by ingesting and digesting bacteria. Eosinophils and basophils respond to allergic reactions and are capable of ingesting antigen-antibody complexes. Monocytes phagocytose bacteria and release interferon to stimulate the immune system. Lymphocytes are divided into T-cells and B-cells. T-cell immunity is cellular and involves the activation of phagocytes and B-cell immunity uses antibodies to fight infection. Both elevated and low leukocyte counts can be markers of infection and malignancy, and low leukocyte counts are associated with a variety of primary and secondary immunodeficiencies, depending on the WBC type(s) that are out of range. (Mosby's manual of diagnostic and laboratory tests, Kathleen Deska Pagana; Timothy James Pagana, Elsevier St. Louis, Mo ©2010) Source: Regenstrief LOINC

Reference Information

Observation Required in Panel

Required

Fully-Specified Name

Component

Lymphocytes/Leukocytes

Property

NFr

Time

Pt

System

Bld

Scale

Qn

Method

Automated count

Basic Attributes

Class

HEM/BC

Type

Laboratory

First Released

Version 1.0

Last Updated

Version 2.79 (NAM)

Change Reason

Release 2.79: COMPONENT: Triggered by Coll w SCT: This is a specific fraction case where the denominator is percentage or /100. Because the logic is that the percentage piece is captured by Property: NFr (Numeric Fraction), and by Unit: %, therefore, it is redundant to include "100" in the component;

Order vs. Observation

Observation

Common Test Rank Get Info

37

Member of these Panels

Language Variants Get Info

Related Names

• Auto
• Automated detection
• Blood
• Elec
• Elect
• Electr
• HEMATOLOGY/CELL COUNTS
• Leuc
• Leuk
• Leukocyte
• Lkcs
• Lymp
• Lymph
• Lympho
• Lymphocyte
• Lymphs
• Lymphs%
• Number fraction
• Percent
• Point in time
• QNT
• Quan
• Quant
• Quantitative
• Random
• WB
• WBC
• WBCs
• White blood cell
• White blood cells
• Whole blood

Example Units

Related Codes

42250-1 Variant lymphocytes/Leukocytes in Blood by Automated count

Term Description

CLSI (formerly NCCLS) document "Reference Leukocyte Differential Count (Proportional) and Evaluation of Instrumental Methods", 1992, recommend the use of variant lymphocytes rather than atypical or reactive lymphocytes.

Part Descriptions

LP15072-9   Lymphocytes.variant
Variant lymphocytes (also called reactive or atypical) are a type of abnormal lymphocyte found in the peripheral blood. They can be a marker for certain viral illnesses, including infectious mononucleosis, viral hepatitis, CMV, HIV, and rubella, and can also occur as part of a drug reaction to drugs such as phenytoin and para-aminosalicylic acid. [NCBI Books: NBK263] Source: Regenstrief LOINC , NCBI Books: NBK263

LP157588-7   Leukocytes
Leukocytes or white blood cells (WBCs) are immune cells that fight infection, neoplasms and other inflammatory conditions, and mediate allergic responses. There are five types of WBCs normally present in the circulation that are all derived from a similar stem cell in the bone marrow. The five type of WBCs are divided into two groups based on the presence or absence of granules in the cytoplasm. The granulocytes include the neutrophils, basophils and eosinophils. The non-granulocytes include the lymphocytes and the monocytes. The neutrophils fight infection by ingesting and digesting bacteria. Eosinophils and basophils respond to allergic reactions and are capable of ingesting antigen-antibody complexes. Monocytes phagocytose bacteria and release interferon to stimulate the immune system. Lymphocytes are divided into T-cells and B-cells. T-cell immunity is cellular and involves the activation of phagocytes and B-cell immunity uses antibodies to fight infection. Both elevated and low leukocyte counts can be markers of infection and malignancy, and low leukocyte counts are associated with a variety of primary and secondary immunodeficiencies, depending on the WBC type(s) that are out of range. (Mosby's manual of diagnostic and laboratory tests, Kathleen Deska Pagana; Timothy James Pagana, Elsevier St. Louis, Mo ©2010) Source: Regenstrief LOINC

Observation Required in Panel

Conditional

Fully-Specified Name

Component

Lymphocytes.variant/Leukocytes

Property

NFr

Time

Pt

System

Bld

Scale

Qn

Method

Automated count

Basic Attributes

Class

HEM/BC

Type

Laboratory

First Released

Version 2.16

Last Updated

Version 2.79 (NAM)

Change Reason

Release 2.79: COMPONENT: Triggered by Coll w SCT: This is a specific fraction case where the denominator is percentage or /100. Because the logic is that the percentage piece is captured by Property: NFr (Numeric Fraction), and by Unit: %, therefore, it is redundant to include "100" in the component;

Order vs. Observation

Observation

Common Test Rank Get Info

8879

Member of these Panels

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Related Names

• Atypical lymphocytes
• Auto
• Automated detection
• Blood
• Elec
• Elect
• Electr
• HEMATOLOGY/CELL COUNTS
• Leuc
• Leuk
• Leukocyte
• Lkcs
• Lymp
• Lymph
• Lympho
• Lymphocyte
• Lymphs
• Lymphs%
• Number fraction
• Percent
• Point in time
• QNT
• Quan
• Quant
• Quantitative
• Random
• Reactive lymphocytes
• Variant lymphocytes
• Variant Lymphs
• WB
• WBC
• WBCs
• White blood cell
• White blood cells
• Whole blood

Example Units

5905-5 Monocytes/Leukocytes in Blood by Automated count

Part Descriptions

LP14313-8   Monocytes
A monocyte is a mononuclear leukocyte, intimately involved in the initiaton of an immune response. It also protects against blood-borne pathogens and migrates quickly to sites of infection in the tissues. Monocytes are usually identified in stained smears by their large bilobed nucleus. They are produced by the bone marrow from hematopoietic stem cell precursors called monoblasts. The monoblast is the first stage of monocyte maturation. The developmental stages (4 subtypes) of the monocytes are: monoblast, promonocyte, immature monocyte, and mature monocyte. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia , Monocytes

LP14313-8   Monocytes
Large, phagocytic mononuclear leukocytes, produced in the vertebrate bone marrow and released into the blood. Monocytes contain a large, oval or somewhat indented nucleus surrounded by a large cytoplasm and numerous organelles. Source: National Library of Medicine, MeSH 2006

LP157588-7   Leukocytes
Leukocytes or white blood cells (WBCs) are immune cells that fight infection, neoplasms and other inflammatory conditions, and mediate allergic responses. There are five types of WBCs normally present in the circulation that are all derived from a similar stem cell in the bone marrow. The five type of WBCs are divided into two groups based on the presence or absence of granules in the cytoplasm. The granulocytes include the neutrophils, basophils and eosinophils. The non-granulocytes include the lymphocytes and the monocytes. The neutrophils fight infection by ingesting and digesting bacteria. Eosinophils and basophils respond to allergic reactions and are capable of ingesting antigen-antibody complexes. Monocytes phagocytose bacteria and release interferon to stimulate the immune system. Lymphocytes are divided into T-cells and B-cells. T-cell immunity is cellular and involves the activation of phagocytes and B-cell immunity uses antibodies to fight infection. Both elevated and low leukocyte counts can be markers of infection and malignancy, and low leukocyte counts are associated with a variety of primary and secondary immunodeficiencies, depending on the WBC type(s) that are out of range. (Mosby's manual of diagnostic and laboratory tests, Kathleen Deska Pagana; Timothy James Pagana, Elsevier St. Louis, Mo ©2010) Source: Regenstrief LOINC

Reference Information

Observation Required in Panel

Conditional

Fully-Specified Name

Component

Monocytes/Leukocytes

Property

NFr

Time

Pt

System

Bld

Scale

Qn

Method

Automated count

Basic Attributes

Class

HEM/BC

Type

Laboratory

First Released

Version 1.0

Last Updated

Version 2.79 (NAM)

Change Reason

Release 2.79: COMPONENT: Triggered by Coll w SCT: This is a specific fraction case where the denominator is percentage or /100. Because the logic is that the percentage piece is captured by Property: NFr (Numeric Fraction), and by Unit: %, therefore, it is redundant to include "100" in the component;

Order vs. Observation

Observation

Common Test Rank Get Info

36

Member of these Panels

Language Variants Get Info

Related Names

• Auto
• Automated detection
• Blood
• Elec
• Elect
• Electr
• HEMATOLOGY/CELL COUNTS
• Leuc
• Leuk
• Leukocyte
• Lkcs
• Mono
• Monocyte
• Monos
• Number fraction
• Percent
• Point in time
• QNT
• Quan
• Quant
• Quantitative
• Random
• WB
• WBC
• WBCs
• White blood cell
• White blood cells
• Whole blood

Example Units

Related Codes

713-8 Eosinophils/Leukocytes in Blood by Automated count

Part Descriptions

LP14539-8   Eosinophils
Granular leukocytes with a nucleus that usually has two lobes connected by a slender thread of chromatin. The cytoplasm contains coarse, round and uniform granules stainable by eosin. Source: National Library of Medicine, MeSH 2006

LP157588-7   Leukocytes
Leukocytes or white blood cells (WBCs) are immune cells that fight infection, neoplasms and other inflammatory conditions, and mediate allergic responses. There are five types of WBCs normally present in the circulation that are all derived from a similar stem cell in the bone marrow. The five type of WBCs are divided into two groups based on the presence or absence of granules in the cytoplasm. The granulocytes include the neutrophils, basophils and eosinophils. The non-granulocytes include the lymphocytes and the monocytes. The neutrophils fight infection by ingesting and digesting bacteria. Eosinophils and basophils respond to allergic reactions and are capable of ingesting antigen-antibody complexes. Monocytes phagocytose bacteria and release interferon to stimulate the immune system. Lymphocytes are divided into T-cells and B-cells. T-cell immunity is cellular and involves the activation of phagocytes and B-cell immunity uses antibodies to fight infection. Both elevated and low leukocyte counts can be markers of infection and malignancy, and low leukocyte counts are associated with a variety of primary and secondary immunodeficiencies, depending on the WBC type(s) that are out of range. (Mosby's manual of diagnostic and laboratory tests, Kathleen Deska Pagana; Timothy James Pagana, Elsevier St. Louis, Mo ©2010) Source: Regenstrief LOINC

Reference Information

Observation Required in Panel

Conditional

Fully-Specified Name

Component

Eosinophils/Leukocytes

Property

NFr

Time

Pt

System

Bld

Scale

Qn

Method

Automated count

Basic Attributes

Class

HEM/BC

Type

Laboratory

First Released

Version 1.0

Last Updated

Version 2.79 (NAM)

Change Reason

Release 2.79: COMPONENT: Triggered by Coll w SCT: This is a specific fraction case where the denominator is percentage or /100. Because the logic is that the percentage piece is captured by Property: NFr (Numeric Fraction), and by Unit: %, therefore, it is redundant to include "100" in the component;

Order vs. Observation

Observation

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41

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Related Names

• Auto
• Automated detection
• Blood
• Elec
• Elect
• Electr
• Eos
• Eosin
• Eosino
• Eosinophil
• Eosins
• HEMATOLOGY/CELL COUNTS
• Leuc
• Leuk
• Leukocyte
• Lkcs
• Number fraction
• Percent
• Point in time
• QNT
• Quan
• Quant
• Quantitative
• Random
• WB
• WBC
• WBCs
• White blood cell
• White blood cells
• Whole blood

Example Units

Related Codes

706-2 Basophils/Leukocytes in Blood by Automated count

Part Descriptions

LP14328-6   Basophils
Basophils are granular white blood cells characterized by a pale-staining nucleus with 2 to 3 lobes and a cytoplasm containing coarse, dark-staining granules of variable size. They represent 0.5-1% of circulating leukocytes and they are stained by basic dyes. When activated, they release histamine, leukotrienes and a number of cytokines. Source: National Library of Medicine, MeSH 2006

LP157588-7   Leukocytes
Leukocytes or white blood cells (WBCs) are immune cells that fight infection, neoplasms and other inflammatory conditions, and mediate allergic responses. There are five types of WBCs normally present in the circulation that are all derived from a similar stem cell in the bone marrow. The five type of WBCs are divided into two groups based on the presence or absence of granules in the cytoplasm. The granulocytes include the neutrophils, basophils and eosinophils. The non-granulocytes include the lymphocytes and the monocytes. The neutrophils fight infection by ingesting and digesting bacteria. Eosinophils and basophils respond to allergic reactions and are capable of ingesting antigen-antibody complexes. Monocytes phagocytose bacteria and release interferon to stimulate the immune system. Lymphocytes are divided into T-cells and B-cells. T-cell immunity is cellular and involves the activation of phagocytes and B-cell immunity uses antibodies to fight infection. Both elevated and low leukocyte counts can be markers of infection and malignancy, and low leukocyte counts are associated with a variety of primary and secondary immunodeficiencies, depending on the WBC type(s) that are out of range. (Mosby's manual of diagnostic and laboratory tests, Kathleen Deska Pagana; Timothy James Pagana, Elsevier St. Louis, Mo ©2010) Source: Regenstrief LOINC

Reference Information

Observation Required in Panel

Conditional

Fully-Specified Name

Component

Basophils/Leukocytes

Property

NFr

Time

Pt

System

Bld

Scale

Qn

Method

Automated count

Basic Attributes

Class

HEM/BC

Type

Laboratory

First Released

Version 1.0

Last Updated

Version 2.79 (NAM)

Change Reason

Release 2.79: COMPONENT: Triggered by Coll w SCT: This is a specific fraction case where the denominator is percentage or /100. Because the logic is that the percentage piece is captured by Property: NFr (Numeric Fraction), and by Unit: %, therefore, it is redundant to include "100" in the component;

Order vs. Observation

Observation

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42

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Related Names

• Auto
• Automated detection
• Baso
• Basophil
• Basos
• Blood
• Bph
• Elec
• Elect
• Electr
• HEMATOLOGY/CELL COUNTS
• Leuc
• Leuk
• Leukocyte
• Lkcs
• Number fraction
• Percent
• Point in time
• QNT
• Quan
• Quant
• Quantitative
• Random
• WB
• WBC
• WBCs
• White blood cell
• White blood cells
• Whole blood

Example Units

Related Codes

58409-4 Other cells/Leukocytes in Blood by Automated count

Part Descriptions

LP157588-7   Leukocytes
Leukocytes or white blood cells (WBCs) are immune cells that fight infection, neoplasms and other inflammatory conditions, and mediate allergic responses. There are five types of WBCs normally present in the circulation that are all derived from a similar stem cell in the bone marrow. The five type of WBCs are divided into two groups based on the presence or absence of granules in the cytoplasm. The granulocytes include the neutrophils, basophils and eosinophils. The non-granulocytes include the lymphocytes and the monocytes. The neutrophils fight infection by ingesting and digesting bacteria. Eosinophils and basophils respond to allergic reactions and are capable of ingesting antigen-antibody complexes. Monocytes phagocytose bacteria and release interferon to stimulate the immune system. Lymphocytes are divided into T-cells and B-cells. T-cell immunity is cellular and involves the activation of phagocytes and B-cell immunity uses antibodies to fight infection. Both elevated and low leukocyte counts can be markers of infection and malignancy, and low leukocyte counts are associated with a variety of primary and secondary immunodeficiencies, depending on the WBC type(s) that are out of range. (Mosby's manual of diagnostic and laboratory tests, Kathleen Deska Pagana; Timothy James Pagana, Elsevier St. Louis, Mo ©2010) Source: Regenstrief LOINC

LP65491-0   Other cells
"Other cells" refer to cells that are present in blood or body fluid that are not classified elsewhere in the report. The type of cells will vary depending on the method or instrument used. Source: Regenstrief LOINC

Observation Required in Panel

Conditional

Fully-Specified Name

Component

Other cells/Leukocytes

Property

NFr

Time

Pt

System

Bld

Scale

Qn

Method

Automated count

Basic Attributes

Class

HEM/BC

Type

Laboratory

First Released

Version 2.30

Last Updated

Version 2.79 (NAM)

Change Reason

Release 2.79: COMPONENT: Triggered by Coll w SCT: This is a specific fraction case where the denominator is percentage or /100. Because the logic is that the percentage piece is captured by Property: NFr (Numeric Fraction), and by Unit: %, therefore, it is redundant to include "100" in the component;

Order vs. Observation

Observation

Member of these Panels

Language Variants Get Info

Related Names

• Auto
• Automated detection
• Blood
• Cell
• Cellularity
• Elec
• Elect
• Electr
• HEMATOLOGY/CELL COUNTS
• Leuc
• Leuk
• Leukocyte
• Lkcs
• Number fraction
• Othr
• Percent
• Point in time
• QNT
• Quan
• Quant
• Quantitative
• Random
• WB
• WBC
• WBCs
• White blood cell
• White blood cells
• Whole blood

Example Units

751-8 Neutrophils [#/volume] in Blood by Automated count

Term Description

Automated instrumentation performs white blood cell count and calculates the absolute neutrophil count.
Source: Regenstrief Institute

Part Descriptions

LP14267-6   Neutrophils
Neutrophils are the most common form of white blood cells in healthy adults. Neutrophils are approximately 13 micrometers in diameter and have segmented nuclei with 3-5 lobes that are connected by thin strands of chromatin. (Practical Haematology; Barbara J. Bain, Imelda Bates, Mike A. Laffan,S. Mitchell Lewis; Eleventh edition; 2012) Neutrophils function to fight infection by both engulfing microorganisms and secreting lethal enzymes.
(https://www.ncbi.nlm.nih.gov/pubmedhealth/PMHT0022058/) They are produced in the bone marrow and their primary function is to fight infection. Neutrophil numbers increase in the blood in response to acute bacterial infection, inflammation, necrosis or chronic myelogenous leukemia. Neutrophil levels are decreased in the following conditions: aplastic anemia, autoimmune disorder, cancer, chemotherapy, myelodysplastic syndrome and during a negative reaction to drugs. PMID: 24050624 [MedlinePlus Encyclopedia:19864] Source: Regenstrief LOINC

Reference Information

Observation Required in Panel

Optional

Fully-Specified Name

Component

Neutrophils

Property

NCnc

Time

Pt

System

Bld

Scale

Qn

Method

Automated count

Basic Attributes

Class

HEM/BC

Type

Laboratory

First Released

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30

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Related Names

• #
• ABS
• absolute
• absolutes
• Auto
• Automated detection
• Blood
• Cnt
• Count
• Count/volume
• CT
• Elec
• Elect
• Electr
• HEMATOLOGY/CELL COUNTS
• Neut
• Neutr
• Neutrophil
• Number concentration
• Number Concentration (count/vol)
• PMN
• PNM
• Point in time
• QNT
• Quan
• Quant
• Quantitative
• Random
• WB
• Whole blood

Example Units

30229-9 Band form neutrophils [#/volume] in Blood by Automated count

Part Descriptions

LP15070-3   Neutrophils.band form
A band cell (or band neutrophil) is a white blood cell undergoing granulopoiesis. It is derived from a metamyelocyte which eventually will become a mature granulocyte. In contrat to other neutrophils, band neutrophils possess a curved nucleus rather than a lobar one. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia , Wikipedia

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Fully-Specified Name

Component

Neutrophils.band form

Property

NCnc

Time

Pt

System

Bld

Scale

Qn

Method

Automated count

Basic Attributes

Class

HEM/BC

Type

Laboratory

First Released

Version 2.04

Last Updated

Version 2.73 (MIN)

Order vs. Observation

Observation

Common Test Rank Get Info

8737

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Related Names

• #
• ABS
• absolute
• absolutes
• Auto
• Automated detection
• Bands
• Blood
• bnd
• Cnt
• Count
• Count/volume
• CT
• Elec
• Elect
• Electr
• HEMATOLOGY/CELL COUNTS
• N-Band
• Neut
• Neutr
• Neutrophil
• Neuts Band
• Number concentration
• Number Concentration (count/vol)
• PMN
• PNM
• Point in time
• QNT
• Quan
• Quant
• Quantitative
• Random
• WB
• Whole blood

Example Units

731-0 Lymphocytes [#/volume] in Blood by Automated count

Term Description

Automated instrumentation performs white blood cell count and calculates the absolute lymphocyte count.
Source: Regenstrief Institute

Part Descriptions

LP14540-6   Lymphocytes
White blood cells formed in lymphoid tissue. The nucleus is round or ovoid with coarse, irregularly clumped chromatin whereas the cytoplasm is typically pale blue with azurophilic (if any) granules. Most lymphocytes can be classified as either T cells (transit through the thymus), B cells or natural killer cells (NK). Source: National Library of Medicine, MeSH 2006

LP14540-6   Lymphocytes
A lymphocyte is a type of white blood cell in the vertebrate immune system.

A lymphocyte count is usually part of a peripheral complete blood cell count and is expressed as percentage of lymphocytes to total white blood cells counted. A general increase in the number of lymphocytes is known as lymphocytosis whereas a decrease is lymphocytopenia.

An increase in lymphocyte concentration is usually a sign of a viral infection (in some rare case, leukemias are found through an abnormally raised lymphocyte count in an otherwise normal person).

A low normal to low absolute lymphocyte concentration is associated with increased rates of infection after surgery or trauma. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia , Lymphocytes (Wikipedia)

Reference Information

Observation Required in Panel

Optional

Fully-Specified Name

Component

Lymphocytes

Property

NCnc

Time

Pt

System

Bld

Scale

Qn

Method

Automated count

Basic Attributes

Class

HEM/BC

Type

Laboratory

First Released

Version 1.0

Last Updated

Version 2.73 (MIN)

Order vs. Observation

Observation

Common Test Rank Get Info

33

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Related Names

• #
• ABS
• absolute
• absolutes
• Auto
• Automated detection
• Blood
• Cnt
• Count
• Count/volume
• CT
• Elec
• Elect
• Electr
• HEMATOLOGY/CELL COUNTS
• Lymp
• Lymph
• Lympho
• Lymphocyte
• Lymphs
• Lymphs%
• Number concentration
• Number Concentration (count/vol)
• Point in time
• QNT
• Quan
• Quant
• Quantitative
• Random
• WB
• Whole blood

Example Units

Related Codes

43743-4 Variant lymphocytes [#/volume] in Blood by Automated count

Term Description

CLSI (formerly NCCLS) document "Reference Leukocyte Differential Count (Proportional) and Evaluation of Instrumental Methods", 1992, recommend the use of variant lymphocytes rather than atypical or reactive lymphocytes.

Part Descriptions

LP15072-9   Lymphocytes.variant
Variant lymphocytes (also called reactive or atypical) are a type of abnormal lymphocyte found in the peripheral blood. They can be a marker for certain viral illnesses, including infectious mononucleosis, viral hepatitis, CMV, HIV, and rubella, and can also occur as part of a drug reaction to drugs such as phenytoin and para-aminosalicylic acid. [NCBI Books: NBK263] Source: Regenstrief LOINC , NCBI Books: NBK263

Observation Required in Panel

Conditional

Fully-Specified Name

Component

Lymphocytes.variant

Property

NCnc

Time

Pt

System

Bld

Scale

Qn

Method

Automated count

Basic Attributes

Class

HEM/BC

Type

Laboratory

First Released

Version 2.17

Last Updated

Version 2.73 (MIN)

Order vs. Observation

Both

Common Test Rank Get Info

2888

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Related Names

• #
• ABS
• absolute
• absolutes
• Atypical lymphocytes
• Auto
• Automated detection
• Blood
• Cnt
• Count
• Count/volume
• CT
• Elec
• Elect
• Electr
• HEMATOLOGY/CELL COUNTS
• Lymp
• Lymph
• Lympho
• Lymphocyte
• Lymphs
• Lymphs%
• Number concentration
• Number Concentration (count/vol)
• Point in time
• QNT
• Quan
• Quant
• Quantitative
• Random
• Reactive lymphocytes
• Variant lymphocytes
• Variant Lymphs
• WB
• Whole blood

Example Units

742-7 Monocytes [#/volume] in Blood by Automated count

Term Description

Automated instrumentation performs white blood cell count and calculates the absolute monocyte count.
Source: Regenstrief Institute

Part Descriptions

LP14313-8   Monocytes
A monocyte is a mononuclear leukocyte, intimately involved in the initiaton of an immune response. It also protects against blood-borne pathogens and migrates quickly to sites of infection in the tissues. Monocytes are usually identified in stained smears by their large bilobed nucleus. They are produced by the bone marrow from hematopoietic stem cell precursors called monoblasts. The monoblast is the first stage of monocyte maturation. The developmental stages (4 subtypes) of the monocytes are: monoblast, promonocyte, immature monocyte, and mature monocyte. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia , Monocytes

LP14313-8   Monocytes
Large, phagocytic mononuclear leukocytes, produced in the vertebrate bone marrow and released into the blood. Monocytes contain a large, oval or somewhat indented nucleus surrounded by a large cytoplasm and numerous organelles. Source: National Library of Medicine, MeSH 2006

Reference Information

Observation Required in Panel

Optional

Fully-Specified Name

Component

Monocytes

Property

NCnc

Time

Pt

System

Bld

Scale

Qn

Method

Automated count

Basic Attributes

Class

HEM/BC

Type

Laboratory

First Released

Version 1.0

Last Updated

Version 2.73 (MIN)

Order vs. Observation

Observation

Common Test Rank Get Info

32

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Related Names

• #
• ABS
• absolute
• absolutes
• Auto
• Automated detection
• Blood
• Cnt
• Count
• Count/volume
• CT
• Elec
• Elect
• Electr
• HEMATOLOGY/CELL COUNTS
• Mono
• Monocyte
• Monos
• Number concentration
• Number Concentration (count/vol)
• Point in time
• QNT
• Quan
• Quant
• Quantitative
• Random
• WB
• Whole blood

Example Units

Related Codes

711-2 Eosinophils [#/volume] in Blood by Automated count

Term Description

Automated instrumentation performs white blood cell count and calculates the absolute eosinophil count.
Source: Regenstrief Institute

Part Descriptions

LP14539-8   Eosinophils
Granular leukocytes with a nucleus that usually has two lobes connected by a slender thread of chromatin. The cytoplasm contains coarse, round and uniform granules stainable by eosin. Source: National Library of Medicine, MeSH 2006

Reference Information

Observation Required in Panel

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Fully-Specified Name

Component

Eosinophils

Property

NCnc

Time

Pt

System

Bld

Scale

Qn

Method

Automated count

Basic Attributes

Class

HEM/BC

Type

Laboratory

First Released

Version 1.0

Last Updated

Version 2.73 (MIN)

Order vs. Observation

Both

Common Test Rank Get Info

34

Member of these Panels

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Related Names

• #
• ABS
• absolute
• absolutes
• Auto
• Automated detection
• Blood
• Cnt
• Count
• Count/volume
• CT
• Elec
• Elect
• Electr
• Eos
• Eosin
• Eosino
• Eosinophil
• Eosins
• HEMATOLOGY/CELL COUNTS
• Number concentration
• Number Concentration (count/vol)
• Point in time
• QNT
• Quan
• Quant
• Quantitative
• Random
• UniversalLabOrders
• WB
• Whole blood

Example Units

Related Codes

704-7 Basophils [#/volume] in Blood by Automated count

Part Descriptions

LP14328-6   Basophils
Basophils are granular white blood cells characterized by a pale-staining nucleus with 2 to 3 lobes and a cytoplasm containing coarse, dark-staining granules of variable size. They represent 0.5-1% of circulating leukocytes and they are stained by basic dyes. When activated, they release histamine, leukotrienes and a number of cytokines. Source: National Library of Medicine, MeSH 2006

Reference Information

Observation Required in Panel

Optional

Fully-Specified Name

Component

Basophils

Property

NCnc

Time

Pt

System

Bld

Scale

Qn

Method

Automated count

Basic Attributes

Class

HEM/BC

Type

Laboratory

First Released

Version 1.0

Last Updated

Version 2.73 (MIN)

Order vs. Observation

Observation

Common Test Rank Get Info

31

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Related Names

• #
• ABS
• absolute
• absolutes
• Auto
• Automated detection
• Baso
• Basophil
• Basos
• Blood
• Bph
• Cnt
• Count
• Count/volume
• CT
• Elec
• Elect
• Electr
• HEMATOLOGY/CELL COUNTS
• Number concentration
• Number Concentration (count/vol)
• Point in time
• QNT
• Quan
• Quant
• Quantitative
• Random
• WB
• Whole blood

Example Units

Related Codes

51383-8 Leukocytes other [#/volume] in Blood by Automated count

Part Descriptions

LP17393-7   Leukocytes other
"Other cells" refer to cells that are present in blood or body fluid that are not classified elsewhere in the report. The type of cells will vary depending on the method or instrument used. Source: Regenstrief LOINC

Observation Required in Panel

Optional

Fully-Specified Name

Component

Leukocytes other

Property

NCnc

Time

Pt

System

Bld

Scale

Qn

Method

Automated count