Version 2.78

Part Description

LP16714-5   Histone
Histones are small nuclear proteins that together with dsDNA, represent a nucleosome, the structural unit of chromatin. Anti-histone antibodies are associated with various autoimmune diseases, including systemic lupus erythematosus (SLE), rheumatoid arthritis, Sjogren's syndrome, systemic sclerosis, infectious diseases (including HIV), and some neurological disorders such as Alzheimer's disease and dementia. Nearly all patients with drug-induced SLE have anti-histone antibodies, but they are also present in patients with idiopathic forms of the disease. One study showed a correlation between SLE with positive anti-dsDNA, anti-nucleosome and anti-histone antibodies and renal disease, including proliferative glomerulonephritis. PMID: 24649358 Source: Regenstrief LOINC, PMID: 24649358

Fully-Specified Name

Component
Histone Ab
Property
PrThr
Time
Pt
System
Ser
Scale
Ord
Method
IA

Additional Names

Short Name
Histone Ab Ser Ql IA
Display Name
Histone Ab IA Ql (S)
Consumer Name Alpha Get Info
Histone antibody, Blood

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.32
Last Updated
Version 2.73
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both
Common Test Rank Get Info
7203

Member of these Panels

LOINC Long Common Name
88883-4 Connective tissue autoimmune Ab panel - Serum

Member of these Groups Get Info

LOINC Group Group Name
LG21281-7 Histone Ab|PrThr|Pt|ANYBldSerPl

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Histona Anticuerpos:PrThr:Punto temporal:Suero:Ord:IA
es-MX Spanish (Mexico) Histona Ab:Presencia o umbral:Punto temporal:Suero:Ordinal:Inmunoensayo
et-EE Estonian (Estonia) Histoon antikehad:PrThr:Pt:S:Ord:IA
Synonyms: Järgarvuline Juhuslik Seerum
fr-CA French (Canada) Histone, Ac:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:IA
fr-FR French (France) Histones anticorps:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Immunoanalyse
fr-BE French (Belgium) Histone Ac:PrThr:Temps ponctuel:Sérum:Ordinal:IA
Synonyms: Anticorps
it-IT Italian (Italy) Istone Ab:PrThr:Pt:Siero:Ord:IA
Synonyms: anticorpo Immunoassay Presenza o Soglia Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant
nl-NL Dutch (Netherlands) histon As:aanwezigheid:moment:serum:ordinaal:immunoassay
Synonyms: antistof; antilichaam IA
pt-BR Portuguese (Brazil) Histona Ac::Pt:Soro:Ord:Imunoensaio
ru-RU Russian (Russian Federation) Гистон Ат:PrThr:ТчкВрм:Сыв:Пор:IA
Synonyms: Антитело Порядковый Сыворотка Точка во времени;Момент
tr-TR Turkish (Turkey) Histon Ab:MevcEşik:Zmlı:Ser:Srl:İA
Synonyms: Ak İmmünölçüm, immünoassay Mevcut
zh-CN Chinese (China) 组蛋白 抗体:存在情况或阈值:时间点:血清:序数型:免疫测定法
Synonyms: Ab;自身抗体 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 时刻;随机;随意;瞬间 组朊 组朊 Ab 组朊抗体 组蛋白 Ab 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=58765-9