Version 2.78

Status Information

Status
TRIAL

Term Description

A biospecimen is collected from the respondent to measure cotinine, a marker of either smoking or of environmental tobacco smoke exposure. One of the most common methods is via a urine sample obtained from the respondent. Cotinine in urine is measured by gas chromatography mass spectrometry (GC-MS). Other biological matrices (blood, hair, saliva) may be used to measure cotinine. Information about collection and analysis of those matrices is found in the Supplemental Information: Blood, Hair, and Saliva Assays for Tobacco Smoke Exposure. Caffeine may interfere with the accuracy of the results. During the gas chromatography analysis, this interference can be minimized by ramping up the temperature and eluting the caffeine later than the cotinine.
Source: Regenstrief LOINC

Reference Information

Type Source Reference
Article Consensus measures for Phenotypes and Exposures Man, C. N., L.-H. Gam, Ismail, S., Lajis, R., Awang, R. 2006. Simple, rapid and sensitive assay method for simultaneous quantification of urinary nicotine and cotinine using gas chromatography-mass spectrometry. J of Chromatography B 844(2): 322-327.
Article Consensus measures for Phenotypes and Exposures Bernowitz, N.L. (1999). Biomarkers of Environmental Tobacco Smoke Exposure. Environ Health Perspect. 107(Suppl 2):3 49-355.
Article Consensus measures for Phenotypes and Exposures Kuo, H.W., Yang, J.S., Chiu, M.C. (2002). Determination of urinary and salivary cotinine using gas and liquid chromatography and enzyme-linked immunosorbent assay. J Chromatogr B Analyt Technol Biomed Life Sci. 768(2):297-303.
Article Consensus measures for Phenotypes and Exposures Dhar, Preeti. (2004). Measuring tobacco smoke exposure: quantifying nicotine/cotinine concentration in biological samples by colorimetry, chromatography and immunoassay methods. J Pharm Biomed Anal, 35(2004), 155-168.
Article Consensus measures for Phenotypes and Exposures Benowitz, Neal L. (1996). Cotinine as a biomarker of environmental tobacco smoke exposure. Epidemiol Rev, 18(2), 188-204.

Panel Hierarchy

Details for each LOINC in Panel LHC-Forms

LOINC Name R/O/C Cardinality Example UCUM Units
62641-6 PhenX - respiratory - urine assay for tobacco smoke exposure protocol 091701
Indent10366-3 Cotinine [Mass/volume] in Urine O ng/mL

Fully-Specified Name

Component
PhenX - respiratory - urine assay for tobacco smoke exposure protocol 091701
Property
-
Time
Pt
System
^Patient
Scale
-
Method
PhenX

Additional Names

Long Common Name
PhenX - respiratory - urine assay for tobacco smoke exposure protocol 091701
Short Name
Resp urine assay smoke exp proto

Survey Question

Source
PX091701

Basic Attributes

Class
PANEL.PHENX
Type
Clinical
First Released
Version 2.36
Last Updated
Version 2.66
Change Reason
Updated the PhenX ID from "PhenX.<ID>" to "PX<ID>" in Survey Question Source field to align with the variable identifier used in the PhenX Toolkit.; Added the PhenX protocol ID to the Component to clearly define the protocol version for which this panel is based upon.
Panel Type
Panel

Member of these Panels

LOINC Long Common Name
62611-9 PhenX domain - Respiratory

Language Variants Get Info

Tag Language Translation
es-MX Spanish (Mexico) PhenX - respiratorio - análisis de orina para el protocolo de exposición al humo de tabaco 091701:-:Punto temporal:^ Paciente:-:PhenX
it-IT Italian (Italy) PhenX - respiratorio - esame delle urine per l'esposizione al fumo di tabacco, protocollo:-:Pt:^Paziente:-:PhenX
Synonyms: Panel PhenX paziente PhenX Punto nel tempo (episodio)
ru-RU Russian (Russian Federation) PhenX - дыхание - мочи анализ для подтверждения табакокурения протокол:-:ТчкВрм:^Пациент:-:PhenX
Synonyms: Точка во времени;Момент
zh-CN Chinese (China) PhenX - 呼吸系统 - 烟草烟雾暴露尿液检测方案 091701:-:时间点:^患者:-:PhenX
Synonyms: Consensus measures for Phenotypes and eXposures;PhenX;暴露;接触;表型与暴露共识指标;表现型与暴露共识指标;表型与暴露公认指标 Consensus measures for Phenotypes and eXposures;表型与暴露共识指标;表现型与暴露共识指标;表型与暴露公认指标 PhenX - 呼吸系统 - 烟草烟雾暴露（接触）尿液检测（分析）方案 091701;Consensus measures for Phenotypes and eXposures;PhenX;暴露;接触;表型与暴露共识指标;表现型与暴露共识指标;表型与暴露公认指标 医嘱套餐 医嘱套餐类 医嘱套餐组 医嘱组 医嘱组.PhenX;组套（组合、医嘱组、套餐、套餐医嘱、医嘱套餐、组合申请、组合项目）.PhenX;Consensus measures for Phenotypes and eXposures;PhenX;表型与暴露共识指标;表现型与暴露共识指标;表型与暴露公认指标;PhenX 医嘱组 医嘱组合 医嘱组合类 医嘱组套 医嘱组套类 医嘱组类 医疗服务对象;客户;病人;病患;病号;超系统 - 病人 多重;多重型;多重标尺类型;多重精度类型 套餐 套餐医嘱 套餐医嘱组 套餐医嘱组类 实验室医嘱套餐 实验室医嘱套餐类 实验室医嘱组 实验室医嘱组合类 实验室医嘱组套 实验室医嘱组套类 实验室套餐医嘱组 实验室套餐医嘱组类 实验室检验项目医嘱组合类 实验室检验项目组合类 时刻;随机;随意;瞬间 曝光 检验医嘱组合类 检验项目医嘱组合类 检验项目组合类 组 组合 组合医嘱 组合类 组套 辐照

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=62641-6
Questionnaire definition
https://fhir.loinc.org/Questionnaire/?url=http://loinc.org/q/62641-6