69038-8
Lymphocyte proliferation.phytohemagglutinin.maximum/CD45 in Blood by Flow cytometry (FC)
Active
Part Descriptions
LP135736-9 Lymphocyte proliferation.phytohemagglutinin.maximum
Lymphocyte proliferation is used in the evaluation of patients with primary and secondary immunodeficiency diseases which affect T lymphocytes. Plant mitogens, including phytohemagglutinin [PHA] and pokeweed [PWM], are capable of inducing blastogenesis and stimulating lymphocyte proliferation. The panel is used to assess T cell function in patients having immunosuppressive therapy and to evaluate patients with cellular or humoral immunodeficiency diseases, which include SCID (Severe Combined Immunodeficiency), CVID (Common Variable Immunodeficiency), and DiGeorge syndrome.
Source: Regenstrief Institute
LP135736-9 Lymphocyte proliferation.phytohemagglutinin.maximum
Lymphocyte proliferation to antigens and mitogens is performed by flow cytometry using a thymidine analogue called Edu®. Total lymphocytes are identified using a combination of the CD45 marker and FSC/SSC parameters, and total T cells with the CD3 marker from within the lymphocyte population. Three concentrations each for Candida (CA) and Tetanus (TT) (same for mitogens) are used and only the result at the concentration of antigen/mitogen that gives maximal response for that individual (since this can vary from person to person) is reported. The maximal % antigen-specific proliferating lymphocytes (CD45+) (numerator) relative to the total CD45+ lymphocyte population (denominator) is assessed. For T cells, the maximal response where the % CD3+ proliferating antigen-specific T cells is expressed relative to the total CD3+ T cell population is assessed.
The maximum as referred to above is the concentration of antigen or mitogen that gives the highest proliferating response.
Copyright Copyright © 1995-2009
Source: Mayo Medical Laboratories
Fully-Specified Name
- Component
- Lymphocyte proliferation.phytohemagglutinin.maximum/CD45
- Property
- NFr
- Time
- Pt
- System
- Bld
- Scale
- Qn
- Method
- Flow cytometry
Additional Names
- Long Common Name
- Lymphocyte proliferation.phytohemagglutinin.maximum/CD45 in Blood by Flow cytometry (FC)
- Short Name
- LPT PHA max/CD45 NFr Bld FC
- Display Name
- Lymphocyte proliferation.phytohemagglutinin.maximum/CD45 FC (Bld)
- Consumer Name Alpha Get Info
- Lymphocyte proliferation.phytohemagglutinin.maximum/CD45, Blood
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.38
- Last Updated
- Version 2.73 (MIN)
- Order vs. Observation
- Observation
- Common Test Rank Get Info
- 6065
Member of these Panels
LOINC | Long Common Name |
---|---|
69018-0 | Lymphocyte proliferation mitogen panel - Blood by Flow cytometry (FC) |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
el-GR | Greek (Greece) | Πολλαπλασιασμός λεμφοκυττάρων.φυτοαιμοσυγκολλητίνη.μέγιστος/CD45: Synonyms: CD45 NFr Λεμφοκύτταρο Πολλαπλασιασμός λεμφοκυττάρων Πολλαπλασιασμός λεμφοκυττάρων.φυτοαιμοσυγκολλητίνη.μέγιστος |
es-ES | Spanish (Spain) | Proliferación de linfocitos.Fitohematoaglutinina. máximo/CD45: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | Proliferación de linfocitos, fitohemaglutinina, máximo / CD45: |
fr-FR | French (France) | Lymphocytes prolifération maximale après phytohémagglutinine/CD45: |
it-IT | Italian (Italy) | Linfociti, proliferazione.fitoemoagglutinina.massimo/CD45: Synonyms: Citometria a flusso (FC) Frazione numerica Proliferazione dei linfociti Proliferazione linfocitaria.fitoemoagglutinina.mas Punto nel tempo (episodio) Sangue Sierologia (anticorpi e la maggior parte degli ant |
nl-NL | Dutch (Netherlands) | lymfocytenproliferatie.fytohemagglutinine.maximum/CD45: |
pl-PL | Polish (Poland) | Proliferacja limfocytu.fitohemaglutynina.maksymalna odpowiedź/CD45: Synonyms: CD45 Limfocyt Proliferacja limfocytu Proliferacja limfocytu fitohemaglutynina maksymalna odpowiedź Proliferacja limfocytu fitohemaglutynina maksymalna odpowiedź/CD45 |
ru-RU | Russian (Russian Federation) | Лимфоцит пролиферация.фитогемагглютинин.max/CD45: Synonyms: Количественный Количество отношение Кровь Точка во времени; |
tr-TR | Turkish (Turkey) | Lenfosit proliferasyonu.fitotohemagglutinin.maksimum/CD45: Synonyms: Akış hücremetresi |
zh-CN | Chinese (China) | 淋巴细胞增殖.植物血凝素.最大值/CD45: Synonyms: B220 B220; |
Example Units
Unit | Source |
---|---|
% | Example UCUM Units |
% | REGENSTRIEF |
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LOINC Copyright
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