7016-9

Gentamicin [Susceptibility] by Gradient strip

Active

Part Descriptions

LP15747-6   Gentamicin
Gentamicin is an aminoglycoside antibiotic, which has a bactericidal mode of action binding to the ribosome and various ribozymes to inhibit protein synthesis. Gentamicin is a hydrophilic molecule and is considered to have limited capacity to penetrate eukaryotic cells. Administered intravenously or intramuscularly, gentamicin is used to treat many bacterial infections, particularly gram-negative organisms such as meningitis, and infections of the blood, abdomen, lungs, skin, bones, joints and urinary tract, and is often used to treat severe cases of tularemia and the plague. The effect of gentamicin is mediated through the production of reactive oxygen species (ROS), which causes destablization of iron-sulfur (Fe-S) clusters and generates toxic, bactericidal compounds through the Fenton reaction. Gentamicin may cause kidney, nerve and severe hearing problems. More common side effects include nausea, headache, fever, rash and hoarseness. PMID: 26503658 [MedlinePlus Drug:a682275] Source: Regenstrief LOINC

LP6300-0   Gradient strip
A gradient strip is a reagent strip that contains a predefined concentration gradient of a specific antibiotic or combination of antibiotics that is used for antimicrobial susceptibility testing (AST) and antimicrobial resistance detection (ARD).
For AST, the result is reported in terms of the minimum inhibitory concentration (MIC) of a specific antimicrobial that prevents the visible growth of bacteria. In LOINC, the "Gradient strip" method is used for AST gradient strips that result in an MIC result.
For ARD, the result is reported as the presence or absence of a specific enzyme or other mechanism that confers resistance, which is determined based on comparing the inhibitory concentration (IC) of a specific antimicrobial with the IC of that antimicrobial plus a resistance inhibitor. In LOINC, the "Gradient strip ARD" method is used for ARD gradient strips, which are not intended for determining individual MIC values. Source: Regenstrief LOINC

Fully-Specified Name

Component

Gentamicin

Property

Susc

Time

Pt

System

Isolate

Scale

OrdQn

Method

Gradient strip

Additional Names

Long Common Name

Gentamicin [Susceptibility] by Gradient strip

Short Name

Gentamicin Islt Grad strip

Display Name

Gentamicin Strip [Susc]

Consumer Name Alpha Get Info

Susceptibility to Gentamicin

Basic Attributes

Class

ABXBACT

Type

Laboratory

First Released

Version 1.0h(2)

Last Updated

Version 2.56

Change Reason

Feb 2016-removed "E-test" from the short and long names because the "ETEST" name is trademarked

Order vs. Observation

Observation

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Member of these Groups Get Info

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Related Names

• Aminoglycosides
• ANTIBIOTIC SUSCEPTIBILITIES
• AST
• c213
• Epsilometer
• Estrip
• E-strip
• Garamycin
• Genirr
• Genj
• Gent
• Grad strip
• ID
• Infectious Disease
• InfectiousDisease
• Islt
• Isol
• MIC
• Minimum inhibitory concentration
• Point in time
• Random
• Sus
• Suscept
• Susceptibilities
• Susceptibility
• Susceptibilty

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CodeSystem lookup

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=7016-9

LOINC Copyright

Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.