Version 2.78

Term Description

Autoantibodies (DNA directed) against the RP155 subunit (POLR3A) of RNA polymerase III can be detected by enzyme immunoassays. Results may be interpreted by humans or automated methods and used for the diagnosis of system sclerosis (SSc, diffuse and limited forms) and overlapping syndromes. This code was created for, but not limited to, the detection of RP155 autoantibodies in Euroimmun's Systemic Sclerosis (Nucleoli) Profile EUROLINE (IgG) test kit.
Source: Regenstrief LOINC

Part Description

LP157220-7   RNA polymerase III RP155
POL3RA gene encodes the largest core component (known as RP155) of RNA polymerase III, which synthesizes small RNAs such as 5S rRNA and tRNAs. POL3RA protein is part of the active center of the polymerase. The POL3RA protein plays a key role in sensing and reducing infection by intracellular bacteria and DNA viruses. It also acts as a sensor involved in innate immune response. The presence of antibodies directed against POL3RA are thought to be associated with systemic sclerosis (SSc), a connective tissue disease that affects the skin and internal organs. Source: Regenstrief LOINC

Fully-Specified Name

Component
RNA polymerase III RP155 Ab.IgG
Property
PrThr
Time
Pt
System
Ser/Plas
Scale
Ord
Method
IA

Additional Names

Long Common Name
RNA polymerase III RP155 IgG Ab [Presence] in Serum or Plasma by Immunoassay
Short Name
RNAp III RP155 IgG SerPl Ql IA
Display Name
RNA polymerase III RP155 IgG IA Ql
Consumer Name Alpha Get Info
RNA Polymerase III RP155 IgG antibody, Blood

Example Answer List: LL2206-2

Source: Estonian Society of Laboratory Medicine
Answer Code Score Answer ID
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6
Borderline LA4259-3
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Strong positive LA18996-1

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.42
Last Updated
Version 2.56
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Language Variants Get Info

Tag Language Translation
de-AT German (Austria) Synonyms: RNA Polymerase III (RP155) IgG AK qualitativ
es-ES Spanish (Spain) ARN polimerasa III RP155 IgG:PrThr:Punto temporal:Suero o Plasma:Ord:IA
es-MX Spanish (Mexico) ARN polimerasa III RP155 Ab.IgG:Presencia o umbral:Punto temporal:Suero o Plasma:Ordinal:Inmunoensayo
fr-FR French (France) ARN polymérase III RP155 anticorps IgG:Présence/Seuil:Ponctuel:Sérum/Plasma:Qualitatif:Immunoanalyse
it-IT Italian (Italy) RNA polimerasi III RP155 Ab.IgG:PrThr:Pt:Siero/Plasma:Ord:IA
Synonyms: anticorpi IgG anticorpo Immunoassay Plasma Presenza o Soglia Punto nel tempo (episodio) Siero Siero o Plasma Sierologia (anticorpi e la maggior parte degli ant
nl-NL Dutch (Netherlands) RNA-polymerase III RP155 As.IgG:aanwezigheid:moment:serum of plasma:ordinaal:immunoassay
Synonyms: antistof; antilichaam IA
pt-BR Portuguese (Brazil) RNA polimerase III RP155 Ac.IgG:Limiar:Pt:Soro/Plas:Ord:Imunoensaio
ru-RU Russian (Russian Federation) РНК полимераза III RP155 Ат.IgG:PrThr:ТчкВрм:Сыв/Плаз:Пор:IA
Synonyms: Антитело Плазма Порядковый Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR Turkish (Turkey) RNA polimeraz III RP155 Ab.IgG:MevcEşik:Zmlı:Ser/Plaz:Srl:İA
Synonyms: Ak Ak.IgG İmmünölçüm, immünoassay Mevcut
zh-CN Chinese (China) RNA 聚合酶 III RP155 抗体.IgG:存在情况或阈值:时间点:血清/血浆:序数型:免疫测定法
Synonyms: Ab.IgG;IgG;抗体 IgG Ab;自身抗体 RNA 多聚酶 III RP155;核糖核酸多聚酶 III RP155;核糖核酸聚合酶 III RP155;RNAp III RP155 RNA 多聚酶 III;核糖核酸多聚酶 III;核糖核酸聚合酶 III;RNAp III 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验 免疫球蛋白 G 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 时刻;随机;随意;瞬间 核糖核酸;Ribonucleic acid 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类 血清或血浆

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=72316-3