72328-8
HLA-A+B+C (class I) IgG Ab [Presence] in Serum by Flow cytometry (FC)
Active
Term Description
IgG antibodies to HLA class I antigens (A, B, and C) can be detected by flow cytometry in serum of pre and post-transplant organ recipients. A positive result is an indication of a sensitization to HLA antigens. This code is based on, but not exclusive to, the submitter's test kit, One Lambda's FlowPRA Screening Test, which uses beads coated with common and rare purified HLA Class I or II antigens.
Source: Regenstrief LOINC
Part Description
LP156720-7 HLA-A+B+C Ab.IgG
The major histocompatibility complex (MHC) class I (A, B, and C) and II (DP, DM, DOA, DOB, DQ, and DR) in the human leukocyte antigen (HLA) system contains a large number of genes involved in immune system function in humans. The proteins encoded by some genes form antigens. HLA class I and II antigens are widely distributed on all nucleated cells and carried by platelets.
Antibodies specific to HLA class I and II antigens can be acquired through alloimmunization due to pregnancy, transfusion of blood products, or previous transplants. Alloimmunization can lead to production of antibodies in approximately one third of individuals. The presence of antibodies, specifically IgG, can affect the survival of transplant allografts or transfused platelets in sensitized individuals. Various testing methods are used to detect antibodies to HLA antigens.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- HLA-A+B+C Ab.IgG
- Property
- PrThr
- Time
- Pt
- System
- Ser
- Scale
- Ord
- Method
- Flow cytometry
Additional Names
- Short Name
- HLA-A+B+C IgG Ser Ql FC
- Display Name
- HLA-A+B+C (class I) IgG FC Ql (S)
- Consumer Name Alpha Get Info
- HLA-A+B+C (class I) IgG antibody, Blood
Example Answer List: LL360-9
Source: Regenstrief Institute| Answer | Code | Score | Answer ID |
|---|---|---|---|
| PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) | LA6576-8 | ||
| NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) | LA6577-6 |
Basic Attributes
- Class
- HLA
- Type
- Laboratory
- First Released
- Version 2.42
- Last Updated
- Version 2.56
- Change Reason
- The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 94428-0 | HLA class I and II IgG panel - Serum or Plasma by Flow cytometry (FC) |
| 94446-2 | HLA-A and B and C (class I) IgG panel - Serum or Plasma by Flow cytometry (FC) |
| 72905-3 | Neutrophil Ab and HLA Ab screen panel - Serum or Plasma |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | HLA-A+B+C IgG: |
| es-MX | Spanish (Mexico) | HLA-A + B + C Ab.IgG: |
| et-EE | Estonian (Estonia) | HLA-A+B+C antikehad.IgG: Synonyms: Immuunglobuliin G Järgarvuline Juhuslik Seerum |
| fr-CA | French (Canada) | HLA-A+B+C, IgG: |
| fr-FR | French (France) | HLA-A+B+C anticorps IgG: |
| fr-BE | French (Belgium) | HLA-A+B+C Anticorps. IgG: Synonyms: Anticorps |
| it-IT | Italian (Italy) | HLA-A+B+C Ab.IgG: Synonyms: anticorpi IgG anticorpo Citometria a flusso (FC) HLA tipizzazione tissutale antigeni-anticorpi Presenza o Soglia Punto nel tempo (episodio) Siero |
| nl-NL | Dutch (Netherlands) | HLA-A+B+C As.IgG: Synonyms: antistof; |
| pt-BR | Portuguese (Brazil) | HLA-A+B+C Ac.IgG: |
| ru-RU | Russian (Russian Federation) | HLA-A+B+C Ат.IgG: Synonyms: Антитело Порядковый Сыворотка Точка во времени; |
| tr-TR | Turkish (Turkey) | HLA-A+B+C Ab.IgG: Synonyms: Ak Ak.IgG Akış hücremetresi Mevcut |
| zh-CN | Chinese (China) | HLA-A+B+C 抗体.IgG: Synonyms: A 型 A,B 型; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=72328-8
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.
Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.
LOINC Copyright
Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright