Version 2.78

72525-9 Raltegravir [Susceptibility] by Genotype method

Part Descriptions

LP102418-3   Raltegravir
Raltegravir (MK-0518, brand name Isentress) is an antiretroviral drug used to treat HIV infection. It is the first of a new class of HIV drugs, the integrase inhibitors. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

LP102418-3   Raltegravir
Raltegravir (brand name ISENTRESS) is used in combination with other medications to treat human immunodeficiency virus (HIV) infection. Raltegravir is in a class of medications called HIV integrase strand transfer inhibitors. It works by slowing the spread of HIV in the body. Raltegravir does not cure HIV infection and may not prevent patients from developing HIV-related illnesses. Raltegravir does not prevent affected individuals from spreading HIV. Source: PubMed Health, Raltegravir

Fully-Specified Name

Component
Raltegravir
Property
Susc
Time
Pt
System
Isolate
Scale
Ord
Method
Genotyping

Additional Names

Panel Name
Short Name
Raltegravir Islt Genotyp
Display Name
Raltegravir Genotyping [Susc]
Consumer Name Alpha Get Info
Susceptibility to Raltegravir

Basic Attributes

Class
ABXBACT
Type
Laboratory
First Released
Version 2.42
Last Updated
Version 2.73
Change Reason
Corrected Scale from OrdQn to Ord because Genotyping does not produce a quantitative susceptibility result
Order vs. Observation
Both
Common Test Rank Get Info
14400

Example Answer List LL1908-4

Answer Code Score Answer ID
Sensitive LA16549-0
Resistant LA6676-6
Resistance possible LA17970-7

Member of these Panels

LOINC Long Common Name
49660-4 HIV susceptibility panel by Genotype method

Member of these Groups Get Info

LOINC Group Group Name
LG41441-3 RaltegravirSusc|Isolate

Language Variants Get Info

Tag Language Translation
es-MX Spanish (Mexico) Raltegravir:Susceptibilidad (microorganismos):Punto temporal:Aislado:Ordinal:Susceptibilidad del genotipo viral
es-ES Spanish (Spain) Raltegravir:Susceptibilidad:Punto temporal:Aislado:Ord:Susceptibilidad al genotipo viral
et-EE Estonian (Estonia) Raltegraviir:Susc:Pt:Is:Ord:Genotüpiseerimine
Synonyms: Isolaat Järgarvuline Juhuslik Tundlikkus
fr-CA French (Canada) Raltégravir:Susceptibilité:Temps ponctuel:Isolat:Ordinal:Génotypage
fr-FR French (France) Raltégravir:Sensibilité:Ponctuel:Isolat:Qualitatif:Génotypage
it-IT Italian (Italy) Raltegravir:Susc:Pt:Isolato:Ord:Genotipizzazione
Synonyms: Punto nel tempo (episodio) Sensibilità (microrganismi) Suscettibilità agli antibiotici Suscettibilità al genotipo virale
nl-NL Dutch (Netherlands) raltegravir:gevoeligheid:moment:isolaat:ordinaal:genotypering
pt-BR Portuguese (Brazil) Raltegravir::Pt:Isolado:OrdQn:Genotipagem
ru-RU Russian (Russian Federation) Ралтегравир:Чув:ТчкВрм:Изолят:Пор:Генотипирование
Synonyms: Вирусного генотипа чувствительность Порядковый Точка во времени;Момент Чувствительность (микроорганизмов)
tr-TR Turkish (Turkey) Raltegravir:Duyr:Zmlı:İzolat:Srl:Genotipleme
zh-CN Chinese (China) 雷特拉韦:抗生素敏感性:时间点:分离株:序数型:基因分型
Synonyms: 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 分离物;分离菌;分离菌株;隔离种群 基因型分型;基因型分析;基因型定型;基因定型;病毒基因型敏感性试验 抗生素敏感性(微生物);敏感性;某种抗微生物制剂对于某个分离株的影响;药物敏感性;药物敏感性(微生物) 抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类 时刻;随机;随意;瞬间 雷特格韦;Raltegravir;N-(4-fluorobenzyl)-5-hydroxy-1-methyl-2-(1-methyl-1-{[(5-methyl-1,3,4-oxadiazol-2-yl)carbonyl]amino}ethyl)-6-oxo-1,6-dihydropyrimidine-4-carboxamide;CAS 518048-05-0;1100750-83-1;C20H21FN6O5

72526-7 Elvitegravir [Susceptibility] by Genotype method

Part Descriptions

LP157318-9   Elvitegravir
Elvitegravir is an integrase strand transfer innhibitor (INSTI) active against the human immunodeficiency virus (HIV). Therapy with elvitegravir may be used in combination with cobicistat (a CYP3A4 inhibitor), emtricitabine and tenofovir (both nucleoside reverse transcriptase inhibitors). The treatment is often associated with increased alanine aminotransferase (ALT) levels in serum with no reports of clinically apparent liver injury.[NIH LiverTox: Elvitegravir] Source: Regenstrief LOINC

Fully-Specified Name

Component
Elvitegravir
Property
Susc
Time
Pt
System
Isolate
Scale
Ord
Method
Genotyping

Additional Names

Panel Name
Short Name
Elvitegravir Islt Genotyp
Display Name
Elvitegravir Genotyping [Susc]
Consumer Name Alpha Get Info
Susceptibility to Elvitegravir

Basic Attributes

Class
ABXBACT
Type
Laboratory
First Released
Version 2.42
Last Updated
Version 2.73
Change Reason
Corrected Scale from OrdQn to Ord because Genotyping does not produce a quantitative susceptibility result
Order vs. Observation
Both
Common Test Rank Get Info
14401

Example Answer List LL1908-4

Answer Code Score Answer ID
Sensitive LA16549-0
Resistant LA6676-6
Resistance possible LA17970-7

Member of these Panels

LOINC Long Common Name
49660-4 HIV susceptibility panel by Genotype method

Language Variants Get Info

Tag Language Translation
es-MX Spanish (Mexico) Elvitegravir:Susceptibilidad (microorganismos):Punto temporal:Aislado:Ordinal:Susceptibilidad del genotipo viral
es-ES Spanish (Spain) Elvitegravir:Susceptibilidad:Punto temporal:Aislado:Ord:Susceptibilidad al genotipo viral
fr-FR French (France) Elvitégravir:Sensibilité:Ponctuel:Isolat:Qualitatif:Génotypage
it-IT Italian (Italy) Elvitegravir:Susc:Pt:Isolato:Ord:Genotipizzazione
Synonyms: Punto nel tempo (episodio) Sensibilità (microrganismi) Suscettibilità agli antibiotici Suscettibilità al genotipo virale
nl-NL Dutch (Netherlands) Elvitegravir:gevoeligheid:moment:isolaat:ordinaal:genotypering
pt-BR Portuguese (Brazil) Elvitegravir::Pt:Isolado:OrdQn:Genotipagem
ru-RU Russian (Russian Federation) Элвитегравир:Чув:ТчкВрм:Изолят:Пор:Генотипирование
Synonyms: Вирусного генотипа чувствительность Порядковый Точка во времени;Момент Чувствительность (микроорганизмов)
tr-TR Turkish (Turkey) Elvitegravir:Duyr:Zmlı:İzolat:Srl:Genotipleme
zh-CN Chinese (China) 埃替格韦:抗生素敏感性:时间点:分离株:序数型:基因分型
Synonyms: 6-(3-Chloro-2-fluorobenzyl)-1-[1(S)-(hydroxymethyl)-2-methylpropyl]-7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid;Elvitegravir;GS-9137，JTK-303;6-(3-chloro-2-fluorobenzyl)-1-[1-(hydroxymethyl)-2-methylpropyl]-7-methoxy-4-oxo-1,4-dihydroquinoline-3 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 分离物;分离菌;分离菌株;隔离种群 基因型分型;基因型分析;基因型定型;基因定型;病毒基因型敏感性试验 抗生素敏感性(微生物);敏感性;某种抗微生物制剂对于某个分离株的影响;药物敏感性;药物敏感性(微生物) 抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类 时刻;随机;随意;瞬间

72857-6 Dolutegravir [Susceptibility] by Genotype method

Part Descriptions

LP157327-0   Dolutegravir
Dolutegravir is an experimental new drug under investigation for the treatment of HIV infection. Dolutegravir is an integrase inhibitor. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

Fully-Specified Name

Component
Dolutegravir
Property
Susc
Time
Pt
System
Isolate
Scale
Ord
Method
Genotyping

Additional Names

Panel Name
Short Name
Dolutegravir Islt Genotyp
Display Name
Dolutegravir Genotyping [Susc]
Consumer Name Alpha Get Info
Susceptibility to Dolutegravir

Basic Attributes

Class
ABXBACT
Type
Laboratory
First Released
Version 2.44
Last Updated
Version 2.73
Change Reason
Corrected Scale from OrdQn to Ord because Genotyping does not produce a quantitative susceptibility result
Order vs. Observation
Both
Common Test Rank Get Info
11628

Member of these Panels

LOINC Long Common Name
49660-4 HIV susceptibility panel by Genotype method

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Dolutegravir:Susceptibilidad:Punto temporal:Aislado:Ord:Susceptibilidad al genotipo viral
es-MX Spanish (Mexico) Dolutegravir:Susceptibilidad (microorganismos):Punto temporal:Aislado:Ordinal:Susceptibilidad del genotipo viral
fr-FR French (France) Dolutégravir:Sensibilité:Ponctuel:Isolat:Qualitatif:Génotypage
it-IT Italian (Italy) Dolutegravir:Susc:Pt:Isolato:Ord:Genotipizzazione
Synonyms: Punto nel tempo (episodio) Sensibilità (microrganismi) Suscettibilità agli antibiotici Suscettibilità al genotipo virale
nl-NL Dutch (Netherlands) dolutegravir:gevoeligheid:moment:isolaat:ordinaal:genotypering
pt-BR Portuguese (Brazil) Dolutegravir::Pt:Isolado:OrdQn:Genotipagem
ru-RU Russian (Russian Federation) Долутегравир:Чув:ТчкВрм:Изолят:Пор:Генотипирование
Synonyms: Вирусного генотипа чувствительность Порядковый Точка во времени;Момент Чувствительность (микроорганизмов)
tr-TR Turkish (Turkey) Dolutegravir:Duyr:Zmlı:İzolat:Srl:Genotipleme
zh-CN Chinese (China) 度鲁特韦:抗生素敏感性:时间点:分离株:序数型:基因分型
Synonyms: Tivicay;德特格韦;德罗格韦;GSK1349572;第二代整合酶抑制剂;艾滋病治疗药物;CAS 1051375-16-6;C20H19F2N3O5;(4R,12aS)-N-[(2,4-二氟苯基)甲基]-3,4,6,8,12,12a-六氢-7-羟基-4-甲基-6,8-二氧代-2H-吡啶并[1'',2'':4,5]吡嗪并[2,1-b][1,3]噁嗪-9-甲酰胺;(4R,12aS)-N-[(2,4-Difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydr 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 分离物;分离菌;分离菌株;隔离种群 基因型分型;基因型分析;基因型定型;基因定型;病毒基因型敏感性试验 抗生素敏感性(微生物);敏感性;某种抗微生物制剂对于某个分离株的影响;药物敏感性;药物敏感性(微生物) 抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类 时刻;随机;随意;瞬间

90080-3 Bictegravir [Susceptibility] by Genotype method

Part Descriptions

LP268150-2   Bictegravir
Bictegravir is a drug used to treat human immunodeficiency virus (HIV). It is an integrase inhibitor which prevents HIV from replicating. There is some evidence that suggests bictegravir could be effective on strains of HIV that have become resistant to other HIV drugs.[https://aidsinfo.nih.gov/drugs/570/bictegravir/0/patient] Source: Regenstrief LOINC

Fully-Specified Name

Component
Bictegravir
Property
Susc
Time
Pt
System
Isolate
Scale
Ord
Method
Genotyping

Additional Names

Panel Name
Short Name
Bictegravir Islt Genotyp
Display Name
Bictegravir Genotyping [Susc]
Consumer Name Alpha Get Info
Susceptibility to Bictegravir

Basic Attributes

Class
ABXBACT
Type
Laboratory
First Released
Version 2.65
Last Updated
Version 2.69
Change Reason
Release 2.69: SYSTEM: Updated System to "Isolate" since this concept is about the susceptibility of the viral isolate to the drug, not the susceptibility of the specimen to the drug.;
Order vs. Observation
Both

Preferred Answer List LL5075-8

Answer Code Score Answer ID
Susceptible LA24225-7
Potential low-level resistance LA29301-1
Low-level resistance LA29302-9
Intermediate resistance LA29303-7
High-level resistance LA29304-5

Member of these Panels

LOINC Long Common Name
49660-4 HIV susceptibility panel by Genotype method

Language Variants Get Info

Tag Language Translation
es-MX Spanish (Mexico) Bictegravir:Susceptibilidad (microorganismos):Punto temporal:Aislado:Ordinal:Susceptibilidad del genotipo viral
es-ES Spanish (Spain) Bictegravir:Susceptibilidad:Punto temporal:Aislado:Ord:Susceptibilidad al genotipo viral
fr-FR French (France) Bictégravir:Sensibilité:Ponctuel:Isolat:Qualitatif:Génotypage
it-IT Italian (Italy) Bictegravir:Susc:Pt:Isolato:Ord:Genotipizzazione
Synonyms: Punto nel tempo (episodio) Sensibilità (microrganismi) Suscettibilità agli antibiotici Suscettibilità al genotipo virale
nl-NL Dutch (Netherlands) bictegravir:gevoeligheid:moment:isolaat:ordinaal:genotypering
zh-CN Chinese (China) 比克替拉韦:抗生素敏感性:时间点:分离株:序数型:基因分型
Synonyms: 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 分离物;分离菌;分离菌株;隔离种群 基因型分型;基因型分析;基因型定型;基因定型;病毒基因型敏感性试验 抗生素敏感性(微生物);敏感性;某种抗微生物制剂对于某个分离株的影响;药物敏感性;药物敏感性(微生物) 抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类 时刻;随机;随意;瞬间 比卡格韦;CAS 1611493-60-7;HIV-1 整合酶抑制剂

61199-6 HIV 1 integrase gene mutations detected [Identifier]

Fully-Specified Name

Component
HIV 1 integrase gene mutations detected
Property
Prid
Time
Pt
System
Isolate
Scale
Nom
Method

Additional Names

Panel Name
Short Name
HIV1 integrase gene Mut Det Islt
Display Name
HIV 1 integrase gene mutations detected Nom (Isol)
Consumer Name Alpha Get Info
HIV 1 integrase gene variant analysis

Basic Attributes

Class
ABXBACT
Type
Laboratory
First Released
Version 2.34
Last Updated
Version 2.73
Order vs. Observation
Both
Common Test Rank Get Info
10060

Example Answer List LL2323-5

Answer Code Score Answer ID
N155S LA19405-2
F121Y LA19406-0

Member of these Panels

LOINC Long Common Name
75622-1 HIV 1 and 2 tests - Meaningful Use set
49660-4 HIV susceptibility panel by Genotype method

Language Variants Get Info

Tag Language Translation
es-MX Spanish (Mexico) Se detectaron mutaciones en el gen de la integrasa del VIH 1:Presencia o identidad:Punto temporal:Aislado:Nominal:
es-ES Spanish (Spain) Gen de la integrasa del VIH Detección de mutaciones:Presencia o identidad:Punto temporal:Aislado:Nom:
fr-FR French (France) VIH-1 gène intégrase mutations détectées:Identification:Ponctuel:Isolat:Résultat nominal:
it-IT Italian (Italy) HIV, gene integrasi, mutazioni identificate:Prid:Pt:Isolato:Nom:
Synonyms: Gene dell''integrasi dell''HIV Presenza o Identità Punto nel tempo (episodio) Suscettibilità agli antibiotici
nl-NL Dutch (Netherlands) HIV 1 integrase gen gedetecteerde mutaties:identificator:moment:isolaat:nominaal:
pt-BR Portuguese (Brazil) Detecção da mutação do gene HIV integrase:Ident:Pt:Isolado:Nom:
ru-RU Russian (Russian Federation) HIV 1 интегразы ген мутации выявлены:ПрИд:ТчкВрм:Изолят:Ном:
Synonyms: ВИЧ ВИЧ 1 Номинальный;Именной Присутствие или Идентификация Точка во времени;Момент
tr-TR Turkish (Turkey) HIV integraz geni mutasyonlar, saptanmış:MevcKimlik:Zmlı:İzolat:Snf:
uk-UA Ukrainian (Ukraine) Виявлені мутації генів ВІЛ1 РНК інтегрази:Наявність або Ідентифікація:МоментЧасу:Ізолят:Категорійно:
Synonyms: AIDS; ANTIBIOTIC SUSCEPTIBILITIES; HIV type 1; HIV type I; HIV1; HIV1 integrase; HIV1 integrase gene; HIV1 IntInh; Human immunodeficiency virus; i; ID; Identity or presence; Infectious Disease; InfectiousDisease; IntInh; Islt; Isol; Mut; Mut Det; Mutation; Muts; Nominal; Point in time; Random
zh-CN Chinese (China) HIV 1 型整合酶基因 已检出的突变:存在与否或特征标识:时间点:分离株:名义型:
Synonyms: Ⅰ AIDS;AIDS 病毒;人类免疫缺陷病毒;人类免疫缺陷病毒（Human immunodeficiency virus，HIV）;爱滋病;艾滋病;艾滋病病毒;获得性免疫缺陷综合征;获得性免疫缺陷综合征（Acquired Immure Deficiency Syndrome，AIDS，艾滋病） HIV 1 型（人类免疫缺陷病毒 1 型、人类免疫缺陷病毒 I 型、人免疫缺陷病毒 1 型、人免疫缺陷病毒 I 型、HIV I、HIV I 型、艾滋病病毒 I 型）整合酶（IN）基因 HIV1;HTLV 3;HTLV III;人类免疫缺陷病毒 1 型;人类免疫缺陷病毒 I 型;HIV 1 型（人类免疫缺陷病毒 1 型、人类免疫缺陷病毒 I 型、人免疫缺陷病毒 1 型、人免疫缺陷病毒 I 型、HIV I、HIV I 型、艾滋病病毒 I 型） I 分离物;分离菌;分离菌株;隔离种群 分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答 存在;存在与否;特征标识;身份;身份标识 已发现的突变 抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类 时刻;随机;随意;瞬间 突变 突变类;基因突变 遗传基因;遗传因子;吉恩;生物基因