Version 2.78

72887-3 Staphylococcus aureus methicillin resistance SCCmec [Presence] in Nose by NAA with probe detection

Term Description

Detection of nucleic acid sequences specific to staphylococcal cassette chromosome mec (SCCmec), a genomic island found in methicillin-resistance Staphylococcus aureus (MRSA). This term was created for, but not limited in use to, Cepheid's Xpert MRSA/SA Nasal assay, a qualitative real-time PCR test that detects Staphylococcus aureus (SA) and methicillin-resistant Staphylococcus aureus (MRSA) DNA from nasal swabs in patients at risk for nasal colonization. Primers and probes are used to detect sequences of the staphylococcal protein A (spa), the gene for methicillin/oxacillin resistance (mecA), and the staphylococcal cassette chromosome (SCCmec) inserted into the Staphylococcus aureus chromosomal attB site.
Source: Regenstrief LOINC

Part Descriptions

LP171727-3   Staphylococcus aureus methicillin resistance SCCmec
SCCmec, or staphylococcal cassette chromosome mec, is a mobile genetic element of Staphylococcus bacterial species. This genetic sequence includes the mecA gene coding for resistance to the antibiotic methicillin and is the only known way for Staphylococcus strains to spread the gene in the wild by horizontal gene transfer. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, SCCmec

Fully-Specified Name

Component
Staphylococcus aureus methicillin resistance SCCmec
Property
PrThr
Time
Pt
System
Nose
Scale
Ord
Method
Probe.amp.tar

Additional Names

Short Name
SCCmec Nose Ql NAA+probe
Display Name
MRSA SCCmec NAA+probe Ql (Nose)
Consumer Name Alpha Get Info
MRSA SCCmec, Nose

Basic Attributes

Class
ABXBACT
Type
Laboratory
First Released
Version 2.44
Last Updated
Version 2.73
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; Removed parentheses around SCCmec in Component based on our current LOINC model.
Order vs. Observation
Observation
Common Test Rank Get Info
2380

Example Answer List LL360-9

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Member of these Panels

LOINC Long Common Name
72892-3 MRSA SCCmec and mecA genes panel - Nose by NAA with probe detection

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Staphylococcus aureus Methicillin-Resistenz SCCmec:Nachweis oder Schwellenwert:Zeitpunkt:Nase:Ordinal:Zielfragmentamplifikation mit Sondendetektion
de-AT German (Austria) Synonyms: MRSA (SCCmec) ql. /N PCR
es-MX Spanish (Mexico) Staphylococo aureus resistencia a la meticilina SCCmec:Presencia o umbral:Punto temporal:Nariz:Ordinal:Amplificación de ácidos nucleicos con detección de sonda
es-ES Spanish (Spain) Staphylococcus aureus resistente a meticilina (SCCmec):PrThr:Punto temporal:Nariz:Ord:Sonda con amplificación dirigida
fr-CA French (Canada) Staphylococcus aureus résistant à la méthicilline SCCmec:Présence-Seuil:Temps ponctuel:Nez:Ordinal:Sonde avec amplification de la cible
fr-FR French (France) Staphylococcus aureus résistance à la méticilline SCCmec gène:Présence/Seuil:Ponctuel:Nez:Qualitatif:PCR amplification de cible
it-IT Italian (Italy) SCCmec Staphylococcal Cassette Chromosome mec:PrThr:Pt:Naso:Ord:Sonda.amp.tar
Synonyms: Presenza o Soglia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA Suscettibilità agli antibiotici
nl-NL Dutch (Netherlands) Staphylococcus aureus meticillineresistentie (SCCmec):aanwezigheid:moment:neus:ordinaal:probe-detectie
Synonyms: MRSA probe.amp.tar
pt-BR Portuguese (Brazil) Staphylococcus cassette cromosomo (SCCmec)::Pt:Nasal:Ord:Sonda com limite de detecção da amplificação de alvo
ru-RU Russian (Russian Federation) Staphylococcus cassette хромосома (SCCmec):PrThr:ТчкВрм:Нос:Пор:Проба.усил.миш
Synonyms: Staphylococcus кассетная хромосома (SCCmec) ДНК проба;ДНК зонд Порядковый Проба с мишени усилением Точка во времени;Момент
tr-TR Turkish (Turkey) Staphylococcus aureus methicillin dirençli (SCCmec):MevcEşik:Zmlı:Burun:Srl:Prob.amf.hdf
Synonyms: Mevcut
zh-CN Chinese (China) 金黄色葡萄球菌甲氧西林耐药 SCCmec:存在情况或阈值:时间点:鼻:序数型:探针法.基因扩增.靶向
Synonyms: 2,6-二甲氧基苯青霉素;二甲氧基苯青霉素;二甲氧苯青霉素;新青霉素;甲氧苯青霉素 依次型;分类顺序型;定性的;序数型(或称等级型);性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 借助扩增的探针方法;借助扩增的探针法;探针法.扩增 借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况(存在、存在与否、是否存在)或阈值(界值、界限、阀值、临界值) 扩增型 扩增性 抗力 抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类 抗耐性 抵抗力 抵抗性 时刻;随机;随意;瞬间 电阻 经过扩增的 耐性 脱氧核糖核酸探针 葡萄状球菌 葡萄球菌属 金葡;金葡菌 金黄色葡萄球菌甲氧西林耐药(抗性、耐性、耐药性、抗药、抗药性、耐受、耐药型) SCCmec;葡萄球菌盒式染色体 SCCmec;葡萄球菌盒染色体 SCCmec;葡萄球菌染色体 mec 基因盒;SCCmec 基因;葡萄球菌染色体 mec 盒 阻力 鼻部

48813-0 Methicillin resistance mecA gene [Presence] by Molecular method

Fully-Specified Name

Component
Bacterial methicillin resistance mecA gene
Property
PrThr
Time
Pt
System
Isolate/Specimen
Scale
Ord
Method
Molgen

Additional Names

Short Name
mecA Islt/Spm Ql
Display Name
Methicillin resistance mecA gene Molgen Ql (Islt/Spec)
Consumer Name Alpha Get Info
Methicillin resistance mecA gene

Basic Attributes

Class
ABXBACT
Type
Laboratory
First Released
Version 2.21
Last Updated
Version 2.73
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; Removed parentheses around gene name in Component based on the current LOINC model.; ; Updated System from "Isolate" and Method from "Probe.amp.tar" according to the new, more sustainable model for LOINC molecular resistance terms [Approved by LOINC Laboratory Committee in June 2018].
Order vs. Observation
Both
Common Test Rank Get Info
3578

Example Answer List LL360-9

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Member of these Panels

LOINC Long Common Name
104991-5 Bacterial resistance panel
85762-3 Blood pathogens panel by NAA with non-probe detection in Positive blood culture
76586-7 ENT microorganism gene identification panel by NAA with probe detection
92789-7 Gram positive blood culture panel by NAA with probe detection in Positive blood culture
72892-3 MRSA SCCmec and mecA genes panel - Nose by NAA with probe detection
97326-3 Staphylococcus aureus identification and resistance panel by Molecular genetics method
99012-7 Urinary tract pathogens panel - Urine by NAA with probe detection
76585-9 Wound microorganism gene identification panel by NAA with probe detection

Language Variants Get Info

Tag Language Translation
de-AT German (Austria) Synonyms: Methicillin Resistenz Gen (MecA) ql.
de-DE German (Germany) Bakterielle Methicillin-Resistenz mecA-Gen:Nachweis oder Schwellenwert:Zeitpunkt:Isolat oder Probenmaterial:Ordinal:Molekulargenetisch
es-MX Spanish (Mexico) Gen mecA de resistencia a la meticilina bacteriana:Presencia o umbral:Punto temporal:Aislado o espécimen:Ordinal:Genética molecular
es-ES Spanish (Spain) Gen mecA bacterias meticilin resistente:PrThr:Punto temporal:Muestra aislada:Ord:Genética molecular
fr-FR French (France) Résistance bactérienne à la méticilline mecA gène:Présence/Seuil:Ponctuel:Isolat/échantillon:Qualitatif:Biologie moléculaire
fr-CA French (Canada) Gène bactérien de résistance à la méthicilline mecA:Présence-Seuil:Temps ponctuel:Isolat/Échantillon:Ordinal:Molgen
it-IT Italian (Italy) Gene mecA di resistenza batterica a meticillina:PrThr:Pt:Isolato/Campione:Ord:Molgen
Synonyms: Gene mecA Genetica molecolare Isolato o Campione Presenza o Soglia Punto nel tempo (episodio) Suscettibilità agli antibiotici
nl-NL Dutch (Netherlands) bacteriële meticillineresistentie mecA-gen:aanwezigheid:moment:isolaat of monster:ordinaal:moleculair genetisch onderzoek
Synonyms: isolaat/specimen molgen
pt-BR Portuguese (Brazil) mecA gene:ACnc:Pt:XXX:Ord:Sonda com limite de detecção da amplificação de alvo
Synonyms: Methicillin resistance gene; Arbitrary concentration; Point in time; Random; Misc; Miscellaneous; Unspecified; Other; Ql; Ordinal; QL; Qualitative; Qual; Screen; PCR; Polymerase chain reaction; Transcription mediated amplification; NASBA; Nucleic acid sequence based analysis; SDA; Strand Displacement Amplification; LAT; Ligation-activated transcription; 3SR SR; 3 Self-Sustaining Sequence Replication; LCR; Ligase chain reaction; QBR; Q-Beta Replicase or probe amplification category method; Probe with target amplification; NAAT; TMA; Amp Prb; Probe with ampification; DNA probe; Amplified; ANTIBIOTIC SUSCEPTIBILITIES
zh-CN Chinese (China) 细菌甲氧西林耐药 mecA 基因:存在情况或阈值:时间点:分离株/标本:序数型:分子遗传学类实验室方法
Synonyms: 2,6-二甲氧基苯青霉素;二甲氧基苯青霉素;二甲氧苯青霉素;新青霉素;甲氧苯青霉素 2,6-二甲氧基苯青霉素抗性基因;2,6-二甲氧基苯青霉素耐药基因;二甲氧基苯青霉素抗性基因;二甲氧基苯青霉素耐药基因;细菌甲氧西林耐药(抗性、耐性、耐药性、抗药、抗药性、耐受、耐药型)(mecA) 基因 供检查用的材料;待检物;待试验物;样品;样本;试料;试样 依次型;分类顺序型;定性的;序数型(或称等级型);性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内,用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应 分离株/标本(样本、样品、试样) 分离物;分离菌;分离菌株;隔离种群 受检物 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况(存在、存在与否、是否存在)或阈值(界值、界限、阀值、临界值) 抗力 抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类 抗耐性 抵抗力 抵抗性 时刻;随机;随意;瞬间 样品 样本 电阻 细菌2,6-二甲氧基苯青霉素耐药 mecA 基因;细菌二甲氧基苯青霉素耐药 mecA 基因;细菌甲氧西林耐药(抗性、耐性、耐药性、抗药、抗药性、耐受、耐药型)mecA 基因;细菌甲氧苯青霉素耐药 mecA 基因 细菌性 细菌的 耐性 试样 遗传基因;遗传因子;吉恩;生物基因 阻力

72891-5 Staphylococcus protein A spa gene [Presence] in Isolate or Specimen by NAA with probe detection

Part Descriptions

LP171728-1   Staphylococcus protein A spa gene
Protein A is a 56 kDa MSCRAMM surface protein originally found in the cell wall of the bacterium Staphylococcus aureus.

As a pathogen Staphylococcus aureus utilizes Protein A, along with a host of other proteins and surface factors to aid its survival and, thus, virulence. Protein A helps inhibit phagocytic engulfment and acts as an immunological disguise. Mutants of S. aureus lacking protein A are more efficiently phagocytosed in vitro, and mutants in infection models have diminished virulence. Higher levels of Protein A in different strains of S. aureus have been associated with nasal carriage of this bacteria. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Protein A

Fully-Specified Name

Component
Staphylococcus protein A spa gene
Property
PrThr
Time
Pt
System
Isolate/Specimen
Scale
Ord
Method
Probe.amp.tar

Additional Names

Short Name
Spa gene Islt/Spm Ql NAA+probe
Display Name
S. protein A spa gene NAA+probe Ql (Islt/Spec)
Consumer Name Alpha Get Info
Staphylococcus Protein A spa gene

Basic Attributes

Class
ABXBACT
Type
Laboratory
First Released
Version 2.44
Last Updated
Version 2.73
Change Reason
Release 2.72: SYSTEM: Updated System from "Nose" to "Isolate/Specimen" according to the LOINC model molecular resistance terms; LONG_COMMON_NAME: Updated System from "Nose" to "Isolate/Specimen" according to the LOINC model molecular resistance terms. Changed the LCN to reflect the update of the system.; Previous Releases: The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; Removed parentheses in Component around "spa" based on current LOINC naming model.
Order vs. Observation
Observation
Common Test Rank Get Info
2399

Example Answer List LL360-9

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Member of these Panels

LOINC Long Common Name
72892-3 MRSA SCCmec and mecA genes panel - Nose by NAA with probe detection

Language Variants Get Info

Tag Language Translation
de-AT German (Austria) Synonyms: MRSA spa-Typisierung /SM
es-MX Spanish (Mexico) Gen spa de la proteína A de Staphylococo:Presencia o umbral:Punto temporal:Nariz:Ordinal:Amplificación de ácidos nucleicos con detección de sonda
es-ES Spanish (Spain) Gen de proteína A de Staphylococcus (spa):PrThr:Punto temporal:Muestra aislada:Ord:Sonda con amplificación dirigida
fr-FR French (France) Staphylococcus protéine A spa gène:Présence/Seuil:Ponctuel:Isolat/échantillon:Qualitatif:PCR amplification de cible
it-IT Italian (Italy) Staphylococcus proteina A, gene (spa):PrThr:Pt:Isolato/Campione:Ord:Sonda.amp.tar
Synonyms: Gene (spa) proteina A dello stafilococco Isolato o Campione Presenza o Soglia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA Suscettibilità agli antibiotici
nl-NL Dutch (Netherlands) Staphylococcus proteïne A-(Spa)-gen:aanwezigheid:moment:isolaat of monster:ordinaal:probe-detectie
Synonyms: isolaat/specimen probe.amp.tar Staphylococcus proteïne A (spa) gen
pt-BR Portuguese (Brazil) Staphylococcus proteína A (spa) gene::Pt:Nasal:Ord:Sonda com limite de detecção da amplificação de alvo
zh-CN Chinese (China) 葡萄球菌蛋白 A (spa) 基因:存在情况或阈值:时间点:分离株/标本:序数型:探针法.基因扩增.靶向
Synonyms: A 型 PR;Prot;成分 - 化学 - 蛋白质类;蛋白;朊;蛋白质类;蛋白质类物质 供检查用的材料;待检物;待试验物;样品;样本;试料;试样 依次型;分类顺序型;定性的;序数型(或称等级型);性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 借助扩增的探针方法;借助扩增的探针法;探针法.扩增 借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向 分离株/标本(样本、样品、试样) 分离物;分离菌;分离菌株;隔离种群 受检物 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况(存在、存在与否、是否存在)或阈值(界值、界限、阀值、临界值) 扩增型 扩增性 抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类 时刻;随机;随意;瞬间 样品 样本 经过扩增的 脱氧核糖核酸探针 葡萄状球菌 葡萄球菌属 葡萄球菌蛋白 A 基因;SPA 基因 试样 遗传基因;遗传因子;吉恩;生物基因