Version 2.78

Term Description

This test measures the phenylalanine to tyrosine ratio in children who have been diagnosed with phenylketonuria and are on a therapeutic diet for their condition. The parent of the patient collects the dried blood spot specimen at home and sends it to the laboratory. This ratio is used together with the phenylalanine and tyrosine levels to monitor the patient's progress. Note: different locations use different monitoring analytes. In some states, tyrosine and phenylalanine levels are used in conjunction with the succinylacetone level instead of the phenylalanine to tyrosine ratio.
Source: Regenstrief LOINC

Part Descriptions

LP15792-2   Phenylalanine
Phenylalanine is an essential alpha-amino acid. It exists in two forms, a D and an L form, which are enantiomers (mirror-image molecules) of each other. It has a benzyl side chain and its name comes from its chemical structures that consists of a phenyl group substituted for one of the hydrogens in the side chain of alanine. Because of its phenyl group, phenylalanine is an aromatic compound that at room temperature exists as a white, powdery solid. L -phenylalanine (LPA) is an electrically-neutral amino acid and its enantiomer, D -phenylalanine (DPA), can be synthesized artificially. L -phenylalanine can also be converted into L -tyrosine, another one of the twenty protein-forming amino acids. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Phenylalanine (Wikipedia)

LP32175-9   Tyrosine
Tyrosine (from the Greek tyros, meaning cheese, as it was first discovered in cheese[ citationneeded ]), 4-hydroxyphenylalanine, or 2-amino-3(4-hydroxyphenyl)-propanoic acid, is one of the 20 amino acids that are used by cells to synthesize proteins. It has a phenol side chain with a hydroxyl group. Upon the location of the hydroxyl group, there are three structural isomers of Tyr, namely para-Tyr (p-Tyr), meta-Tyr (m-Tyr) and ortho-Tyr (o-Tyr). Enzymatically, only the first isomer (p-Tyr) is produced from L-Phe by the Phe-hydroxylase enzyme. The other two isoforms, m-Tyr and o-Tyr can be produced as a consequence of free radical attack on Phe in states with increased oxidative stress. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Tyrosine (Wikipedia)

LP32175-9   Tyrosine
A non-essential amino acid. In animals it is synthesized from PHENYLALANINE. It is also the precursor of EPINEPHRINE; THYROID HORMONES; and melanin. Source: National Library of Medicine, MeSH 2006

Fully-Specified Name

Component
Phenylalanine/Tyrosine^post therapeutic diet
Property
SRto
Time
Pt
System
Bld.dot
Scale
Qn
Method

Additional Names

Short Name
Phe/Tyr p diet DBS-sRto
Display Name
Phenylalanine/Tyrosine post therapeutic diet (DBS) [Molar ratio]
Consumer Name Alpha Get Info
Phenylalanine/Tyrosine - after Therapeutic Diet, Dried blood spot

Basic Attributes

Class
CHAL
Type
Laboratory
First Released
Version 2.46
Last Updated
Version 2.61
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
74874-9 Metabolic disorder therapy monitoring panel - DBS

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Fenilalanina/Tirosina^post dieta terapéutica:Relacion de Sustancia:Punto temporal:gota de sangre (papel de filtro):Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Fenilalanina / Tirosina ^ dieta posterapéutica:Proporción de sustancia:Punto temporal:DBS:Cuantitativo:
fr-FR French (France) Phénylalanine/tyrosine après régime thérapeutique:Moles ratio:Ponctuel:Sang buvard:Numérique:
it-IT Italian (Italy) Fenilalanina/Tirosina^dieta post terapia:Srto:Pt:Sangue.su carta da filtro:Qn:
Synonyms: Punto nel tempo (episodio) Rapporto di sostanza Sangue Spot sangue secco Test di provocazione
nl-NL Dutch (Netherlands) fenylalanine/tyrosine^na therapeutisch dieet:molaire verhouding:moment:gedroogde bloedspot:kwantitatief:
pt-BR Portuguese (Brazil) Fenilalanina/Tirosina^após dieta terapêutica::Pt:SgPapel:Qn:
ru-RU Russian (Russian Federation) Фенилаланин/Тирозин^после терапевтической диеты:МольОтн:ТчкВрм:Кр.Сух.капл:Колич:
Synonyms: Количественный Кровь Кровь сухая капля Мольная доля;Молярная доля;Отношение концентраций Точка во времени;Момент
tr-TR Turkish (Turkey) Fenilalanin/Tirozin^terapötik diyet snr:SOrn:Zmlı:Kan.nokta:Kant:
Synonyms: SubsOranı
zh-CN Chinese (China) 苯丙氨酸/酪氨酸^在治疗性饮食之后:物质的量比率:时间点:全血.斑点:定量型:
Synonyms: 3-对羟苯基丙氨酸;Tyr Phe;PPA;苯基丙氨酸 Phe+Tyr;Phe+Tyrosine;苯丙氨酸与酪氨酸;苯基丙氨酸+酪氨酸;苯基丙氨酸与酪氨酸 PKU Tyr XXX刺激 - 在...之后 之后于... 全血斑点(滤纸);滤纸;血液.斑点;血液斑点(滤纸) 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 在...以后 在后 时刻;随机;随意;瞬间 治疗 治疗性的 治疗性饮食之后;之后于治疗性饮食;在治疗性饮食（治疗膳食、治疗饮食、治疗用饮食、食饵疗法饲料、疗用饲粮）之后 治疗的 物质的量比值;物质的量比;摩尔比;摩尔比率;摩尔比值 疗效饮食;食饵疗法饲料;治疗膳食;治疗饮食 苯丙酮尿 苯丙酮尿症 苯丙酮酸尿症 血;血液 饮食;日常饮食;日常食物;规定饮食;食谱

Example Units

Unit Source
{ratio} Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=74300-5