Version 2.78

Term Description

Monoclonal Protein Peak 1 identification in serum by Immunofixation (IFE). Identification of type of protein present in the peak.
Source: Regenstrief LOINC

Part Descriptions

LP18363-9   Monoclonal band observed
A monoclonal band (M-spike, monoclonal protein isotype) is often found in patients with monoclonal gammopathies. Following protein electrophoresis, immunofixation is used to identify the immunoglobulin heavy chain and/or light chain. Monoclonal peaks greater than 3 g/dL and IgG or IgA are seen in patients with Multiple Myeloma (MM). A monoclonal peak greater than 3 g/dL and IgM is seen in patients with macroglobulinemia. An alternate methodology for identifying the monoclonal protein isotype is MALDI-TOF, in which known information regarding the unique mass of each isotype is used to determine and quantify the isotype present in the patient sample based on the mass spectra generated from the sample. Source: Regenstrief LOINC

LP6336-4   Immunofixation
Plasma or concentrated urine is deposited on a gel. With an electrical current the proteins are sorted in function of their size, after which antigens for each targeted type of immunoglobulin are deposited on the gel. Thus more or less narrow bands appear on the gel, marking the location of the various immunoglobulines.
Immunofixation tends to replace protein electrophoresis because:

• it is faster (results within three hours);
• it is somewhat more sensitive. Immunofixation may reveal an immunoglobulin missed out by protein electrophoresis, especially at low concentrations (less than 1 gram/litre);
• it can be partially automated and can be used in more laboratories;
• it is more easily read and interpreted.

Immunofixation is however only sensitive to immunoglobulins and is more expensive than protein electrophoresis. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Immunofixation

Fully-Specified Name

Component
Monoclonal band observed
Property
Prid
Time
Pt
System
Ser/Plas
Scale
Nom
Method
Immunofixation

Additional Names

Short Name
Monoclon Band Obs SerPl IFE
Display Name
Monoclonal band observed Immunofixation Nom
Consumer Name Alpha Get Info
Monoclonal band observed, Blood

Example Answer List: LL2432-4

Source: Regenstrief LOINC
Answer Code Score Answer ID
Kappa LA19741-0
Lambda LA19742-8

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.48
Last Updated
Version 2.48
Order vs. Observation
Observation

Member of these Groups Get Info

LOINC Group Group Name
LG1438-3 Monoclonal band observed|Prid|Pt|ANYBldSerPl

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Banda monoclonal observada:Presencia o identidad:Punto temporal:Suero o Plasma:Nom:Inmunofijación
es-MX Spanish (Mexico) Banda monoclonal observada:Presencia o identidad:Punto temporal:Suero o Plasma:Nominal:Inmunofijación
fr-CA French (Canada) Bande monoclonale:Présence ou identité:Temps ponctuel:Sérum/Plasma:Nominal:Immunofixation
fr-FR French (France) Bandes monoclonales observées:Identification:Ponctuel:Sérum/Plasma:Résultat nominal:Immunofixation
fr-BE French (Belgium) Bande monoclonale:Présence ou identité:Temps ponctuel:Sérum/Plasma:Nominal:Immunofixation
Synonyms: Présence de bande monoclonale
it-IT Italian (Italy) Banda monoclonale osservata:Prid:Pt:Siero/Plasma:Nom:Immunofissazione
Synonyms: Chimica Plasma Presenza o Identità Punto nel tempo (episodio) Siero Siero o Plasma
nl-NL Dutch (Netherlands) monoclonale band waargenomen:identificator:moment:serum of plasma:nominaal:immunofixatie
pt-BR Portuguese (Brazil) Banda monoclonal observada:Ident:Pt:Soro/Plas:Nom:Imunofixação
ru-RU Russian (Russian Federation) Моноклональная полоса наблюдённая:ПрИд:ТчкВрм:Сыв/Плаз:Ном:Иммунофиксация
Synonyms: Номинальный;Именной Плазма Присутствие или Идентификация Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR Turkish (Turkey) Monoklonal band, gözlenen:MevcKimlik:Zmlı:Ser/Plaz:Snf:İmmünfiksasyon
zh-CN Chinese (China) 已观察到的单克隆区带:存在与否或特征标识:时间点:血清/血浆:名义型:免疫固定电泳分析法
Synonyms: IFE;Ifix;免疫固定法;免疫固定电泳（Immunofixation electrophoresis，IFE）;免疫固定电泳法 分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 区带 单克隆区带观察情况;单克隆条带观察情况;已观察的单克隆条带;已观察的单克隆区带 存在;存在与否;特征标识;身份;身份标识 带 带状 带状核 时刻;随机;随意;瞬间 杆 杆状核 血清或血浆

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CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=74665-1