Version 2.78

Term Description

This panel includes result codes commonly reported as part of a HER2 (ERBB2 gene) amplification in situ hybridization (e.g. FISH) study. The intention of this panel is to provide users with the associated LOINC codes. For LOINC mapping to the order and overall report of a HER2 amplification FISH study, use the ERBB2 gene duplication term [LOINC: 96893-3].
Source: Regenstrief LOINC

Part Description

LP62864-1   FISH
FISH (fluorescence in situ hybridization) is a cytogenetic technique used to detect and localize the presence or absence of specific DNA sequences on chromosomes. FISH uses fluorescent probes that bind to only those parts of the chromosome with which they show a high degree of sequence similarity. Fluorescence microscopy can be used to find out where the fluorescent probe bound to the chromosomes. FISH is often used for finding specific features in DNA for use in genetic counseling, medicine, and species identification. FISH can also be used to detect and localize specific mRNAs within tissue samples. In this context, it can help define the spatial-temporal patterns of gene expression within cells and tissues. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, FISH

Panel Hierarchy

Details for each LOINC in Panel LHC-Forms

LOINC Name R/O/C Cardinality Example UCUM Units
74885-5 ERBB2 gene (HER2) duplication associated observations panel - Tissue by FISH
Indent31150-6 ERBB2 gene duplication [Presence] in Tissue by FISH
Indent49683-6 ERBB2 gene copy number/Chromosome 17 copy number in Tissue by FISH
Indent74860-8 ERBB2 gene copy number/nucleus in Tissue by FISH {#}
Indent74861-6 Chromosome 17 copy number/nucleus in Tissue by FISH {#}
Indent62361-1 Cells counted [#] {#}
Indent19147-8 Referral lab test reference range

Fully-Specified Name

Component
ERBB2 gene duplication associated observations panel
Property
-
Time
Pt
System
Tiss
Scale
-
Method
FISH

Additional Names

Short Name
ERBB2 (HER2) Dup Pnl Tiss FISH
Display Name
ERBB2 gene (HER2) duplication associated observations panel FISH (Tiss)
Consumer Name Alpha Get Info
ERBB2 gene (HER2) duplication associated observations panel, Tissue

Basic Attributes

Class
PANEL.MOLPATH
Type
Laboratory
First Released
Version 2.48
Last Updated
Version 2.70
Change Reason
Release 2.70: COMPONENT: Corrected the gene name based on the LOINC model to use the approved HGNC name for the gene that encodes the HER2 receptor. Also added "gene duplication associated observations" to clarify that this panel contains a set of result codes commonly reported with HER2 amplification FISH studies.;
Order vs. Observation
Order
Panel Type
Panel

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Panel de HER2:Propiedades mixtas (sólo paneles):Punto temporal:Tejido:-:Hibridación in situ fluoresente (FISH)
es-MX Spanish (Mexico) Panel HER2:-:Punto temporal:Tejido y frotis:-:Hibridación fluorescente in situ (FISH)
fr-FR French (France) HER2 panel:-:Ponctuel:Tissu:-:FISH
it-IT Italian (Italy) Osservazioni associate alla duplicazione del gene ERBB2, panel:-:Pt:Tessuto:-:FISH
Synonyms: Gene ERBB2 Ibridazione in situ fluorescente (FISH) Panel osservazioni associate alla duplicazione del gene ERBB2 Patologia molecolare Punto nel tempo (episodio) Set di prescrizione patologia molecolare Tessuto & Strisci
nl-NL Dutch (Netherlands) ERBB2-genduplicatie panel:-:moment:weefsel en uitstrijkjes:-:FISH
Synonyms: ERBB2 gen HER2
pt-BR Portuguese (Brazil) HER2 painel::Pt:Tecido:-:FISH
zh-CN Chinese (China) HER2 组套:-:时间点:组织与涂片:-:FISH
Synonyms: c-erb B2;Her2;HER-2/neu;NGL;TKR1;V-ERB-B2 禽类成红血细胞性白血病病毒性致癌基因同源基因 2 (神经/恶性胶质瘤源性癌基因同源基因);V-ERB-B2 禽类成红血细胞性白血病病毒性致癌基因同源基因 2 (神经/恶性胶质瘤源性致癌基因同源基因);V-ERB-B2 禽类成红血细胞性白血病病毒性致癌基因同源基因 2 (神经/成胶质细胞瘤源性癌基因同源基因);V-ERB-B2 禽类成红血细胞性白血病病毒性致癌基因同源基因 2 (神经/成胶质细胞瘤源性致癌基因同源基因);V- Fluorescent in situ hybridization;荧光原位杂交 HER2 组套（组合、医嘱组、套餐、套餐医嘱、医嘱套餐、组合申请、组合项目） 关联的 分子病理学;分子病理学试验 医嘱套餐 医嘱套餐类 医嘱套餐组 医嘱组 医嘱组.分子病理学;分子病理学组套（组合、医嘱组、套餐、套餐医嘱、医嘱套餐、组合申请、组合项目）;分子病理学医嘱组类;医嘱组类.分子病理学;实验室医嘱组类.分子病理学 医嘱组合 医嘱组合类 医嘱组套 医嘱组套类 医嘱组类 多重;多重型;多重标尺类型;多重精度类型 套餐 套餐医嘱 套餐医嘱组 套餐医嘱组类 实验室医嘱套餐 实验室医嘱套餐类 实验室医嘱组 实验室医嘱组合类 实验室医嘱组套 实验室医嘱组套类 实验室套餐医嘱组 实验室套餐医嘱组类 实验室检验项目医嘱组合类 实验室检验项目组合类 时刻;随机;随意;瞬间 有联系的 未作说明的组织;组织;组织 & 涂片 检验医嘱组合类 检验项目医嘱组合类 检验项目组合类 相关的 组 组合 组合医嘱 组合类 组套 遗传基因;遗传因子;吉恩;生物基因

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=74885-5
Questionnaire definition
https://fhir.loinc.org/Questionnaire/?url=http://loinc.org/q/74885-5