74888-9
Sterols panel [Moles/volume] - Serum or Plasma
Active
Term Description
Determination of sterols (e.g. desmosterol, lathosterol, campesterol, and sitosterol) in serum or plasma is performed to diagnose conditions such as desmosterolosis (desmosterol reductase deficiency) and sitosterolemia. Patients with sitosterolemia are known to develop premature coronary artery disease, cerebrotendinous xanthomatosis (CTX), and Smith-Lemli-Optiz (SLO) syndrome. is performed to assess dietary plant sterol intake and intestinal absorption.
Source: Regenstrief LOINC
Phytosterols (e.g., β-sitosterol, campesterol, stigmasterol, and brassicasterol) are common components of plant foods,such as vegetable oils, seeds, and nuts. An average Western diet contains approx. 200-400 mg of phytosterols per day. Phytosterols are structurally similar to cholesterol and differ only in the number of carbons or double bonds in the side chain. Since serum and tissue phytosterols are derived from intestinal absorption, levels reflect dietary plant sterol intake and intestinal absorption. Markedly increased serum phytosterol concentrations (e.g., β-sitosterol > 50 mg/l) is seen in sitosterolemia, a rare autosomal recessive lipid disorder. These patients develop premature coronary heart disease. A study suggests that even slightly increased campesterol (3.8 ± 1.6 mg/l) and β-sitosterol (3.1 ± 1.1 mg/l) concentrations in serum may contribute to the risk of coronary heart disease. PMID: 15489546
Source: Regenstrief LOINC
Panel Hierarchy
Details for each LOINC in Panel LHC-Forms
LOINC | Name | R/O/C | Cardinality | Example UCUM Units |
---|---|---|---|---|
74888-9 | Sterols panel [Moles/volume] - Serum or Plasma | |||
Indent74907-7 | Beta sitosterol [Moles/volume] in Serum or Plasma | pmol/L | ||
Indent77371-3 | Brassicasterol [Moles/volume] in Serum or Plasma | pmol/L | ||
Indent58464-9 | Campesterol [Moles/volume] in Serum or Plasma | umol/L | ||
Indent74432-6 | Cholestanol [Moles/volume] in Serum or Plasma | umol/L | ||
Indent14647-2 | Cholesterol [Moles/volume] in Serum or Plasma | mmol/L | ||
Indent74433-4 | Cholestanol/Cholesterol in Serum or Plasma | % | ||
Indent32289-1 | 7-Dehydrocholesterol [Moles/volume] in Serum or Plasma | umol/L | ||
Indent56535-8 | 8-Dehydrocholesterol [Moles/volume] in Serum or Plasma | umol/L | ||
Indent74905-1 | Desmosterol [Moles/volume] in Serum or Plasma | pmol/L | ||
Indent74898-8 | Lanosterol [Moles/volume] in Serum or Plasma | pmol/L | ||
Indent77373-9 | Lathosterol [Moles/volume] in Serum or Plasma | pmol/L | ||
Indent74887-1 | Stigmastanol [Moles/volume] in Serum or Plasma | pmol/L | ||
Indent74886-3 | Stigmasterol [Moles/volume] in Serum or Plasma | pmol/L |
Fully-Specified Name
- Component
- Sterols panel
- Property
- SCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- -
- Method
Additional Names
- Short Name
- Sterols Pnl SerPl-sCnc
- Display Name
- Sterols panel [Moles/Vol]
- Consumer Name Alpha Get Info
- Sterols panel, Blood
Basic Attributes
- Class
- PANEL.DRUG/TOX
- Type
- Laboratory
- First Released
- Version 2.48
- Last Updated
- Version 2.50
- Change Reason
- Changed Component name from Phytosterols to Sterols since panel includes both sterols and phytosterols.
- Order vs. Observation
- Order
- Panel Type
- Panel
Member of these Groups Get Info
LOINC Group | Group Name |
---|---|
LG46763-5 | Sterols panel| |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Fitosteroles: |
es-MX | Spanish (Mexico) | Panel de esteroles: |
fr-CA | French (Canada) | Profil des stérols: |
fr-FR | French (France) | Stéroïdes panel: |
it-IT | Italian (Italy) | Steroli, panel: Synonyms: Concentrazione di Sostanza Livelli farmacologici e tossicologia Panel steroli Plasma Punto nel tempo (episodio) Set di prescrizione per livelli farmacologici e to Siero Siero o Plasma |
nl-NL | Dutch (Netherlands) | sterolen panel: |
pt-BR | Portuguese (Brazil) | Fitosterois painel: |
ru-RU | Russian (Russian Federation) | Фитостеролы панель: Synonyms: Молярность; |
zh-CN | Chinese (China) | 甾醇类组套: Synonyms: 克分子浓度; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=74888-9 - Questionnaire definition
- https:
//fhir.loinc.org/Questionnaire/?url=http: //loinc.org/q/74888-9
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