Version 2.78

Term Description

Bacterial identification by MALDI-TOF (matrix-assisted laser desorption ionization time of flight) is a diagnostic test for identifying the specific organism(s) responsible for a bacterial infection. MALDI-TOF is a form of mass spectrometry that analyzes the proteins contained in an isolated bacterial colony. The resulting mass spectrum is compared to a reference database of bacterial protein mass spectra in order to identify the organism(s) present in the test sample. This term was created for, but is not limited in use to, the Bruker Daltonics MALDI Biotyper CA System, which is indicated for use in diagnosing Gram-negative bacterial infections.
Source: Regenstrief LOINC

Part Descriptions

LP14082-9   Bacteria
One of the three domains of life (the others being Eukarya and Archaea), also called Eubacteria. They are unicellular prokaryotic microorganisms which generally possess rigid cell walls and multiply by cell division. They exhibit three principal forms: round or coccal, rodlike or bacillary, and spiral or spirochetal. Bacteria can be classified by their response to oxygen (aerobic, anaerobic, or facultatively anaerobic) and by how they obtain their energy (chemotrophic, i.e. via a chemical reaction or phototrophic, via a light reaction). In addition, chemotrophs obtain their energy from chemicals, lithotrophic from inorganic compounds and organotrophic from organic compounds. Bacteria are also classified by the source carbon that they utilize: heterotrophic, from organic sources or autotrophic, from carbon dioxide. They can also be classified by whether or not they stain (based on the structure of their cell walls) with crystal violet dye: gram-negative or gram-positive. Source: National Library of Medicine, MeSH 2006

LP186074-3   MS.MALDI-TOF
Matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) is a type of mass spectrometry (MS). MALDI-TOF MS consists of three primary steps: 1) mixing the sample with an organic matrix, which provides a scaffolding and also protons for the ionization process; 2) applying a laser to the matrix, which absorbs energy from the laser and releases it into the sample, which causes the sample to desorb and form singly charged ions; and 3) using a flight tube to analyze the mass of the ions, ultimately resulting in a mass spectrum in which the mass-to-charge is plotted against signal intensity. MALDI-TOF is a soft ionization technique, meaning that molecules remain relatively intact during ionization. Because of this property, MALDI-TOF can be used for protein analysis; in contrast, older MS techniques cause extensive protein fragmentation and therefore cannot be used for this purpose. One application of MALDI-TOF is in clinical microbiology; compared to traditional methods, MALDI-TOF is faster and more accurate in identifying specific microorganisms. PMID: 23824373 Source: Regenstrief LOINC, PMID: 23824373

Fully-Specified Name

Component
Bacteria
Property
Prid
Time
Pt
System
Isolate
Scale
Nom
Method
MS.MALDI-TOF

Additional Names

Short Name
Bacteria Islt MS.MALDI-TOF
Display Name
Bacteria identified MS.MALDI-TOF Nom (Isol)
Consumer Name Alpha Get Info
Bacterial test

Example Answer List: LL2991-9

Source: New York State Health (Wadsworth Center)
Answer Code Score Answer ID
Escherichia coliCopyright http://snomed.info/sct ID:112283007 Escherichia coli (organism) LA21335-7
Klebsiella pneumoniae LA21336-5
Salmonella sp LA21368-8
Pseudomonas aeruginosa LA19340-1
Enterobacter cloacae LA21369-6

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.50
Last Updated
Version 2.78
Change Reason
Release 2.78: COMPONENT: Removed "Identified" from the component because it is implied by the Property "Prid";
Order vs. Observation
Both
Common Test Rank Get Info
13359

Member of these Panels

LOINC Long Common Name
97324-8 Carbapenem resistant bacteria identification and resistance panel by Molecular genetics method
97326-3 Staphylococcus aureus identification and resistance panel by Molecular genetics method

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Bakterien identifiziert:Nachweis oder Identität:Zeitpunkt:Isolat:Nominal:MS.MALDI-TOF
Synonyms: Matrix-assisted laser desorption/ionization - Time-of-Flight-Massenspektrometrie
es-ES Spanish (Spain) Bacteria:Presencia o identidad:Punto temporal:Aislado:Nom:MS.MALDI-TOF
es-MX Spanish (Mexico) Bacterias identificadas:Presencia o identidad:Punto temporal:Aislado:Nominal:SRA. MALDI-TOF
fr-FR French (France) Bactérie identifiée:Identification:Ponctuel:Isolat:Résultat nominal:Spectrométrie MALDI-TOF
it-IT Italian (Italy) Batteri:Prid:Pt:Isolato:Nom:MS.MALDI-TOF
Synonyms: Microbiologia Presenza o Identità Punto nel tempo (episodio)
nl-NL Dutch (Netherlands) bacteriën:identificator:moment:isolaat:nominaal:MALDI-TOF
Synonyms: bacterie massaspectometrie; Malditof
zh-CN Chinese (China) 细菌:存在与否或特征标识:时间点:分离株:名义型:MS.MALDI-TOF
Synonyms: 分离物;分离菌;分离菌株;隔离种群 分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答 基质辅助激光解吸/电离飞行时间质谱;基质辅助激光解吸电离飞行时间质谱;基质辅助激光解吸飞行时间质谱;基质辅助激光解析电离飞行时间质谱;Matrix-Assisted Laser Desorption/ Ionization Time of Flight Mass Spectrometry;MALDI-TOF-MS;Matrix-assisted laser desorption ionization-time of flight 存在;存在与否;特征标识;身份;身份标识 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 时刻;随机;随意;瞬间 细菌类;菌

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