Version 2.78

Part Descriptions

LP15333-5   Alanine aminotransferase
Alanine transaminase or ALT is an enzyme (EC 2.6.1.2) also called serum glutamic pyruvic transaminase (SGPT) or alanine aminotransferase (ALAT). It is found in serum and in various bodily tissues, but is most commonly associated with the liver. It catalyzes the two parts of the alanine cycle. It is commonly measured clinically as a part of a diagnostic evaluation of liver health. Significantly elevated levels of ALT often suggest the existence of other medical problems such as viral hepatitis, diabetes, congestive heart failure, bile duct problems, infectious mononucleosis, or myopathy. However, elevated levels of ALT do not automatically mean that medical problems exist. Fluctuation of ALT levels is normal over the course of the day, and ALT levels can also increase in response to strenuous physical exercise. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, ALT

LP15333-5   Alanine aminotransferase
Alanine aminotransferase (ALT) is an enzyme produced primarily in the liver but are also found in the heart, skeletal muscles, pancreas and kidney cells. The main function of ALT is to convert alanine into pyruvate. ALT is released into the bloodstream when cells containing it are damaged. Increased levels of ALT in the blood provide an early indicator of liver damage. ALT is often measured with aspartate aminotransferase (AST) as part of a liver panel. High levels of ALT could indicate hepatitis, obstructed bile ducts, liver tumors, cirrhosis, alcoholism or other liver disorders. [Lab Tests Online:alt/tab/sample] Source: Regenstrief LOINC

Reference Information

Type Source Reference
Mapping Guidance LOINC This term was made to accommodate a laboratory system outside of the US. LOINC currently discourages the use of specimens combining ser/plas and blood in one term (as ser/plas/bld) for two reasons. First, practices usually want to distinguish the two on ordering since whole blood usually implies a point of care test and ser/plas usually implies sending to another location. Second, whole blood tests are usually classified as low complexity (waived) under CLIA regulations, and because waived tests are excluded from the annual COLA report of testing volume (required by the Centers for Medicare and Medicaid Services) and ser/plas tests are not, the two have to be distinguished.
Webcontent Lab Tests Online®Copyright Copyright © 2021 Lab Tests Online. All rights reserved. Alanine Aminotransferase (ALT)

Fully-Specified Name

Component
Alanine aminotransferase
Property
CCnc
Time
Pt
System
Ser/Plas/Bld
Scale
Qn
Method

Additional Names

Short Name
ALT SerPlBld-cCnc
Display Name
ALT (S/P/Bld) [Catalytic activity/Vol]
Consumer Name Alpha Get Info
Alanine Aminotransferase (ALT; SGPT), Blood

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.52
Last Updated
Version 2.68
Change Reason
Release 2.68: DefinitionDescription: Moved to Mapping Guidance section.
Order vs. Observation
Both

Member of these Groups Get Info

LOINC Group Group Name
LG5272-2 Alanine aminotransferase|CCnc|Pt|ANYBldSerPl

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Alanina aminotransferasa:Concentración Catalítica:Punto temporal:Suero, Plasma o Sangre:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Alanina aminotransferasa:Concentración catalítica:Punto temporal:Suero, plasma o sangre:Cuantitativo:
et-EE Estonian (Estonia) Alaniini aminotransferaas:CCnc:Pt:S/P/B:Qn:
Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma Seerum või plasma või veri Veri
fr-CA French (Canada) Alanine aminotransférase:Concentration catalytique:Temps ponctuel:Sérum/Plasma/Sang:Quantitatif:
fr-FR French (France) Alanine aminotransférase:Catalytique/Volume:Ponctuel:Sérum/Plasma/Sang:Numérique:
fr-BE French (Belgium) Alanine aminotransférase, Transaminase GP:Concentration catalytique:Temps ponctuel:Sérum/Plasma/Sang:Quantitatif:
Synonyms: ALT, ALAT, SGPT, GPT
it-IT Italian (Italy) Alanina aminotransferasi:CCnC:Pt:Siero/Plasma/Sangue:Qn:
Synonyms: Chimica Concentrazione Catalitica Plasma Plasma o Sangue Punto nel tempo (episodio) Sangue Siero Siero o Plasma Siero,Plasma o Sangue
nl-NL Dutch (Netherlands) alanine-aminotransferase:enzymatische activiteit/volume:moment:serum of plasma of bloed:kwantitatief:
Synonyms: ALAT
pl-PL Polish (Poland) Aminotransferaza alaninowa:stężenie katalityczne:punkt w czasie:surowica, osocze lub krew:ilościowy:
ru-RU Russian (Russian Federation) Аланин аминотрансфераза:КаталКонц:ТчкВрм:Сыв/Плаз/Кр:Колич:
Synonyms: Аланинаминотрансфераза;АЛТ;АлАт Каталитическая концентрация Количественный Кровь Плазма Сыворотка Сыворотка или Плазма Сыворотка, Плазма или Кровь Точка во времени;Момент
tr-TR Turkish (Turkey) Alanin aminotransferaz:KtlKons:Zmlı:Ser/Plaz/Kan:Kant:
zh-CN Chinese (China) 丙氨酸氨基转移酶:催化浓度:时间点:血清/血浆/全血:定量型:
Synonyms: Ala;Alpha 丙氨酸;Alpha-丙氨酸;L-Ala;L-丙氨酸;α丙氨酸;α-丙氨酸;丙胺酸 ALT;GPT;SGPT;丙氨酸转氨酶;谷丙;谷丙转氨酶;谷氨酸-丙酮酸氨基转移酶;谷氨酸-丙酮酸转氨酶 催化浓度(单位体积);单位体积内酶的单位数 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 血;血液 血浆或全血;血浆/血液;血浆或血液 血清、血浆或全血;血清、血浆或血液;血清/血浆/血液 血清或血浆

Example Units

Unit Source
U/L Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=77144-4