77959-5

Yellow fever virus ns5 gene [Presence] in Cerebral spinal fluid by NAA with non-probe detection

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Term Description

This assay comprises qRT-PCR targeting the ns5 gene in the yellow fever backbone followed by melt curve analysis, which identifies DNA fragments with different nucleotide compositions based on their unique melting temperature. PMID: 18501437 CSF testing is indicated for suspected adverse neurological reactions to the vaccine against yellow fever. Genome detection of CSF yellow fever vaccine in this context is considered diagnostic. In suspected patients, detection of antibodies against yellow fever in CSF should also be requested.

Part Description

LP203622-8 Yellow fever virus ns5 gene
Yellow fever (also called yellow jack, black vomit or vomito negro in Spanish, or sometimes American Plague) is an acute viral disease. It is an important cause of hemorrhagic illness in many African and South American countries despite existence of an effective vaccine. The yellow in the disease name refers to the jaundice that affects some patients. Yellow fever has been a source of several devastating epidemics. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia , Yellow fever virus (Wikipedia)

Fully-Specified Name

Component: Yellow fever virus ns5 gene
Property: PrThr
Time: Pt
System: CSF
Scale: Ord
Method: Non-probe.amp.tar

Additional Names

Long Common Name: Yellow fever virus ns5 gene [Presence] in Cerebral spinal fluid by NAA with non-probe detection
Short Name: YFV ns5 gene CSF Ql NAA+non-probe
Display Name: Yellow fever virus ns5 gene NAA+non-probe Ql (CSF)
Consumer Name Alpha Get Info: Yellow Fever virus Ns5 gene, Spinal fluid

Example Answer List: LL360-9

Source: Regenstrief Institute

Answer	Code	Score	Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value)			LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value)			LA6577-6

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 2.54
Last Updated: Version 2.63 (MIN)
Change Reason: Changed Method from "Melt.amp.tar" to "Non-probe.amp.tar", which includes other non-probe based detection methods while still distinguishing from probe-based methods.; The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation: Both

Member of these Groups Get Info

LOINC Group	Group Name
LG32769-8	Yellow fever virus

Language Variants Get Info

Tag	Language	Translation
de-DE	German (Germany)	Gelbfieber-Virus ns5-Gen:Nachweis oder Schwellenwert:Zeitpunkt:Liquor:Ordinal:Zielfragmentamplifikation mit Detektion ohne Sonde Synonyms: Zerebrospinalflüssigkeit
el-GR	Greek (Greece)	Γονίδιο ns5 ιού κίτρινου πυρετού:PrThr:Pt:ΕΝΥ:Ord:Χωρίς ανιχνευτή.ενίσχυση.στόχου Synonyms: PrThr Γονίδιο Γονίδιο ns5 ιού κίτρινου πυρετού Ιός Ιός κίτρινου πυρετού Πυρετός
es-ES	Spanish (Spain)	gen ns5 del virus de la fiebre amarilla:PrThr:Punto temporal:Líquido Cefalorraquideo:Ord:Amplificación del objetivo no basado en sonda
es-MX	Spanish (Mexico)	Gen ns5 del virus de la fiebre amarilla:Presencia o umbral:Punto temporal:Fluído espinal cerebral:Ordinal:Amplificación de ácidos nucleicos con detección sin sonda
fr-FR	French (France)	Fièvre jaune virus gène ns5:Présence/Seuil:Ponctuel:Liquide céphalorachidien:Qualitatif:Non-PCR amplification de cible
it-IT	Italian (Italy)	Virus della febbre gialla, gene ns5:PrThr:Pt:LCS:Ord:Non-sonda.amp.tar Synonyms: Amplificazione target non basata su sonda Liquido cerebrospinale Microbiologia Presenza o Soglia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA Virus della febbre gialla
zh-CN	Chinese (China)	黄热病病毒 ns5 基因:存在情况或阈值:时间点:脑脊液:序数型:非探针法.基因扩增.靶向 Synonyms: CSF CSF;脊髓液;Cerebral spinal fluid;脑脊髓液 YFV;黄热病毒传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型借助扩增的探针方法;借助扩增的探针法;探针法.扩增借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向借助靶向扩增的非探针方法;借助靶向扩增的非探针法;非探针法.扩增.靶向发烧;热病存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）扩增型扩增性时刻;随机;随意;瞬间经过扩增的脊液脊髓液脑脊液（Cerebral spinal fluid，CSF）脑脊髓液脱氧核糖核酸探针遗传基因;遗传因子;吉恩;生物基因黄热病病毒（YFV、黄热病毒） ns5 基因

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