80382-5

Influenza virus A Ag [Presence] in Upper respiratory specimen by Rapid immunoassay

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Term Description

This term was created for, but is not limited in use to, the Influenza A part of the bioMerieux bioNexia Influenza A+B test, which is intended for the qualitative detection and differentiation of Influenza type A and type B antigens in human nasopharyngeal samples. The results of the bioNexia assay should be read ten minutes after the sample is applied to the sample well.

Part Description

LP14239-5   Influenza virus A
Influenza viruses, from the family Orthomyxoviridae, are enveloped negative-strand RNA viruses with segmented genomes containing seven to eight gene segments. Of the five genera in the family, only influenza A virus (IAV), influenza B and C are medically relevant to humans. Aquatic birds harboring avian IAV are the likely natural reservoir for all known IAV subtypes and are probably the original source of all human pandemic IAV strains. IAV maintained in wild birds have been associated with stable host switch events to novel hosts, including most often to domestic poultry but also to horses, swine, toothed whales and humans. The influenza virus life cycle begins with the binding of viral HA to host cell receptors. Endocytosis and HA-mediated fusion of the viral and cellular membranes occurs. Viral ribonucleoprotein complexes are released into the cytoplasm, travel to the nucleus, then are replicated and transcribed by the viral polymerase complex. The new viruses are formed and bud when the newly formed ribonucleicprotein complexes and structural proteins reach the plasma membrane. Further research is needed to better understand how IAVs switch hosts and the viral genetic changes that underlie human adaptation. IAV causes respiratory infections in humans ranging from asymptomatic to fatal. Pandemics are attributed to "novel" viruses which possess a viral hemagglutinin (HA) to which humans do not have immunity. PMID: 20542248 ] PMID: 25812763
Influenza viruses A and B are single-stranded RNA enveloped viruses belonging to the Orthomyxoviridae family. The symptoms of infection of Influenza A and B include fever, cough, sore throat, rhinorrhea, nasal congestion, headache, myalgia and malaise. Some patients may experience gastrointestinal symptoms including watery diarrhea, vomiting and abdominal pain. The influenza viruses spread rapidly in enclosed spaces with a documented rate of infection of 70% following a common source of exposure. Infection occurs in the respiratory epithelium in both the upper and lower respiratory tract, and the virus can be found in many specimen types, including nasal aspirates, nasal or nasopharyngeal swabs, throat swabs, sputum and tracheal aspirates. When infection rates reach epidemic proportions, hospitalization of children and elderly patients rises as does the mortality rates of elderly patients.(Manual of Clinical Microbiology, 11th edition, James H. Jorgensen; Karen C. Carroll; Guido Funke; Michael A Pfaller; Marie Louise Landry; Sandra S. Richter; David W. Warnock) Source: Regenstrief LOINC

Fully-Specified Name

Component

Influenza virus A Ag

Property

PrThr

Time

Pt

System

Respiratory system specimen.upper

Scale

Ord

Method

IA.rapid

Additional Names

Long Common Name

Influenza virus A Ag [Presence] in Upper respiratory specimen by Rapid immunoassay

Short Name

FLUAV Ag Upper resp Ql IA.rapid

Display Name

FLUAV Ag IA.rapid Ql (Upper resp)

Consumer Name Alpha Get Info

Influenza A (Flu A) antigen, Upper respiratory

Example Answer List: LL744-4

Basic Attributes

Class

MICRO

Type

Laboratory

First Released

Version 2.54

Last Updated

Version 2.77 (MAJ)

Change Reason

Release 2.77: SYSTEM: Updated to standardize the representation of "Respiratory system specimen" in the System subhierarchy across LOINC; Release 2.70: SYSTEM: Updated from "Nph" to make the LOINC term consistent with the original intent to represent a manufacturer's test covering NPH washes and nose swabs, as well as to make it consistent across panel usage.; Previous Releases: Corrected System from "Nasopharynx", which is used for LOINC clinical terms, to "Nph", which is the form used for LOINC lab terms.; The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.

Order vs. Observation

Both

Common Test Rank Get Info

1303

Member of these Panels

Member of these Groups Get Info

Language Variants Get Info

Related Names

• Antigen
• Antigens
• Avian influenza
• Bird flu
• Breathing
• EIA
• ELFA
• ELISA
• Enzyme immunoassay
• FLUA
• FLUAV
• FLUV
• Fowl plague
• IAA
• ID
• Infectious Disease
• InfectiousDisease
• Influ
• Influenza A
• Influenza A virus
• Lungs
• MEIA
• Microbiology
• Ordinal
• Point in time
• PR
• QL
• Qual
• Qualitative
• Random
• RS
• Screen
• Spec
• SUDS
• Up
• Upper resp

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CodeSystem lookup

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LOINC Copyright

Copyright © 2025 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.