Version 2.78

Part Description

LP150045-5   Sequencing
Sequencing is a method used to determine the sequence of individual genes, larger genetic regions (i.e. clusters of genes or operons), full chromosomes or entire genomes. Historically, most sequencing has been performed using the chain termination method developed by Frederick Sanger in 1977. PMID: 271968 Sequencing technologies have improved dramatically, making them cheaper, faster, and more accurate. Next-generation sequencing (NGS), also known as high-throughput sequencing, deep sequencing, and second-generation sequencing, is a type of technology that uses parallel sequencing of multiple small fragments of DNA to determine sequence. This "high-throughput" technology has increased the speed and amount of DNA sequenced at a significantly reduced cost. PMID: 18576944 Several NGS platforms (ie, sequencing instruments and associated reagents) have been developed. Third-generation sequencing is another methodology currently under development that uses parallel sequencing similar to NGS. In contrast to NGS, third-generation sequencing uses single DNA molecules rather than amplified DNA as a template. PMID: 20858600 Source: Regenstrief LOINC

Fully-Specified Name

Component
HIV 1 RNA reverse transcriptase & protease & integrase gene mutations detected
Property
Prid
Time
Pt
System
Plas
Scale
Nom
Method
Sequencing

Additional Names

Short Name
HIV 1 RNA RT + PR + IN Mut Det Plas Seq
Display Name
HIV 1 RNA reverse transcriptase and protease and integrase gene mutations detected Sequencing Nom (P)
Consumer Name Alpha Get Info
HIV 1 RNA Reverse Transcriptase and Protease and Integrase gene variant analysis, Blood

Example Answer List: LL2436-5

Source: Laboratory Corporation of America
Answer Code Score Answer ID
V234L

HIV mutation in the integrase (IN) coding region

 LA24453-5
K13K/E

HIV mutation in the reverse transcriptase (RT) coding region

 LA19752-7
K20R

HIV mutation in the reverse transcriptase (RT) coding region

 LA19753-5
E28D

HIV mutation in the reverse transcriptase (RT) coding region

 LA19754-3
M41M/L

HIV mutation in the reverse transcriptase (RT) coding region

 LA19755-0
G359S

HIV mutation in the reverse transcriptase (RT) coding region

 LA25848-5
V35I

HIV mutation in the reverse transcriptase (RT) coding region

 LA25847-7
K14R

HIV mutation in the integrase (IN) coding region

 LA19756-8
V31I

HIV mutation in the integrase (IN) coding region

 LA19757-6
G193E

HIV mutation in the integrase (IN) coding region

 LA24451-9
D288N

HIV mutation in the integrase (IN) coding region

 LA24454-3
I62V

HIV mutation in the protease (PR) coding region

 LA19758-4
Q18K

HIV mutation in the protease (PR) coding region

 LA25851-9
E35D

HIV mutation in the protease (PR) coding region

 LA25852-7

Basic Attributes

Class
ABXBACT
Type
Laboratory
First Released
Version 2.56
Last Updated
Version 2.73
Order vs. Observation
Both
Common Test Rank Get Info
6046

Member of these Panels

LOINC Long Common Name
75622-1 HIV 1 and 2 tests - Meaningful Use set

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) HIV-1 RNA Reverse Transcriptase & Protease & Integrase-Gene Mutationen entdeckt:Nachweis oder Identität:Zeitpunkt:Plasma:Nominal:Sequenzierung
es-ES Spanish (Spain) Gen de la integrasa, proteasa y transcriptasa inversa del RNA del HIV 1 Detección de mutaciones:Presencia o identidad:Punto temporal:Plasma:Nom:Secuenciación
es-MX Spanish (Mexico) Se detectaron mutaciones en los genes de la transcriptasa inversa, proteasa e integrasa del ARN del VIH 1:Presencia o identidad:Punto temporal:Plasma:Nominal:Secuenciación
fr-FR French (France) VIH-1 ARN gènes reverse transcriptase et protéase et intégrase mutations détectées:Identification:Ponctuel:Plasma:Résultat nominal:Séquençage
it-IT Italian (Italy) HIV 1 proviral,RNA gene trascrittasi inversa& proteasi & integrasi, mutazioni identificate:Prid:Pt:Plasma:Nom:Sequenziamento
Synonyms: Plasma Presenza o Identità Punto nel tempo (episodio) RNA dell''HIV 1 Suscettibilità agli antibiotici
nl-NL Dutch (Netherlands) HIV 1 RNA reverse transcriptase & protease & integrase gen gedetecteerde mutaties:identificator:moment:plasma:nominaal:sequencing
uk-UA Ukrainian (Ukraine) Виявлені мутації генів ВІЛ1 РНК зворотньої транскриптази&протеази & інтегрази:Наявність або Ідентифікація:МоментЧасу:Плазма:Категорійно:Секвенування
Synonyms: AIDS; ANTIBIOTIC SUSCEPTIBILITIES; high-throughput sequencing; HIV 1 RNA RT + PR + IN; HIV type 1; HIV type I; HIV1; HTS; Human immunodeficiency virus; i; ID; Identity or presence; Infectious Disease; InfectiousDisease; Mut; Mut Det; Mutation; Muts; Next generation sequencing; NGS; Nominal; Pl; Plasma; Plsm; Point in time; PR; Random; REV; Ribonucleic acid; RT
zh-CN Chinese (China) HIV 1 型 RNA 逆转录酶与蛋白酶与整合酶基因 已检出的突变:存在与否或特征标识:时间点:血浆:名义型:序列测定
Synonyms: Ⅰ AIDS;AIDS 病毒;人类免疫缺陷病毒;人类免疫缺陷病毒（Human immunodeficiency virus，HIV）;爱滋病;艾滋病;艾滋病病毒;获得性免疫缺陷综合征;获得性免疫缺陷综合征（Acquired Immure Deficiency Syndrome，AIDS，艾滋病） HIV 1 型（人类免疫缺陷病毒 1 型、人类免疫缺陷病毒 I 型、人免疫缺陷病毒 1 型、人免疫缺陷病毒 I 型、HIV I、HIV I 型、艾滋病病毒 I 型） RNA（核糖核酸）逆转录酶（反转录酶、逆录酶、RT）与蛋白酶（Prot）与整合酶（IN）基因 HIV1 RNA HIV1;HTLV 3;HTLV III;人类免疫缺陷病毒 1 型;人类免疫缺陷病毒 I 型;HIV 1 型（人类免疫缺陷病毒 1 型、人类免疫缺陷病毒 I 型、人免疫缺陷病毒 1 型、人免疫缺陷病毒 I 型、HIV I、HIV I 型、艾滋病病毒 I 型） I RT RTase 倒 倒的 倒转 倒转的 分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答 反向 反向的 反常 反常的 反的 反相 反相的 反转录酶 存在;存在与否;特征标识;身份;身份标识 已发现的突变 序列分析;测序 抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类 时刻;随机;随意;瞬间 朊酶 核糖核酸;Ribonucleic acid 相反 相反的 突变 突变类;基因突变 蛋白质酵素 逆 逆的 逆转录酶（Reverse transcriptase，RT） 遗传基因;遗传因子;吉恩;生物基因 颠倒 颠倒的

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=80689-3