Version 2.77

Term Description

A patient's "calculated panel reactive antibody" (cPRA) determines the likelihood that a transplant recipient and donor would be incompatible. The cPRA is calculated based on how many and which HLA antibodies the patient has compared to known information about the HLA antigen frequencies from ~1200 donors from 2003-2005. PMID: 19958328 The more antibodies the patient has and the more common the HLA antigens are in the donor pool, the higher the cPRA. Calculated cPRA is not the same as a patient's percent PRA, which is simply the percentage of a pool of donors (~100) to which a patient had reactive antibodies (see the HLA Ab panel [LOINC: 46993-2]). Note that "panel" is part of the antibody name and a single result is expected. This is not panel term.
Source: Regenstrief LOINC

Fully-Specified Name

Component
Calculated panel reactive antibody
Property
RelRto
Time
Pt
System
Ser
Scale
Qn
Method
Calculated

Additional Names

Short Name
cPRA Ser Calc
Display Name
Calculated panel reactive antibody Calc (S) [Relative ratio]
Consumer Name Alpha Get Info
Calculated panel reactive antibody, Blood

Basic Attributes

Class
HLA
Type
Laboratory
First Released
Version 2.56
Last Updated
Version 2.65
Order vs. Observation
Both

Formula (Readable)

cPRA calculator is available at https://optn.transplant.hrsa.gov/resources/allocation-calculators/cpra-calculator/

Member of these Panels

LOINC Long Common Name
94428-0 HLA class I and II IgG panel - Serum or Plasma by Flow cytometry (FC)
94446-2 HLA-A and B and C (class I) IgG panel - Serum or Plasma by Flow cytometry (FC)
94440-5 HLA-DP and DQ and DR (class II) IgG panel - Serum or Plasma by Flow cytometry (FC)

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Panel de anticuerpos reactivos calculados:Ratio relativo:Punto temporal:Suero:Qn:Calculado
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Anticuerpo reactivo de panel calculado:Razón relativa:Punto temporal:Suero:Cuantitativo:Calculado
fr-FR French (France) Anticorps réactifs panel calculé (cPRA):Ratio relatif:Ponctuel:Sérum:Numérique:Résultat calculé
it-IT Italian (Italy) Panel anticorpi reattivi calcolato:RelRto:Pt:Siero:Qn:Calcolato
Synonyms: HLA tipizzazione tissutale antigeni-anticorpi Punto nel tempo (episodio) Rapporto Relativo Siero
nl-NL Dutch (Netherlands) berekend panel reactieve antistoffen:relatieve verhouding:moment:serum:kwantitatief:berekend
zh-CN Chinese (China) 群体反应性抗体计算值:相对比率:时间点:血清:定量型:计算法
Synonyms: HLA 抗原;人类白细胞抗原;human leukocyte antigen 人白细胞抗原 人类白细胞抗原 人类白细胞抗原（Human Leukocyte Antigen，HLA） 医嘱套餐 医嘱组合 反作用的 反应性 反应性的 反应的 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 套餐 套餐医嘱 时刻;随机;随意;瞬间 来自于不同体系的两种分析物之比;相对比;相对比值 活性的 白细胞抗原 组 组合 组合医嘱 组套 群体反应性抗体校正值;校正型群体反应性抗体;校正群体反应性抗体;计算型群体反应性抗体;计算群体反应性抗体;校正PRA;Calculated PRA;CPRA;cPRA;Calculated panel reactive antibody;Corrected panel reactive antibody 计算;计算型方法

Example Units

Unit Source
{ratio} Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=80737-0