Version 2.79

Term Description

CD3-CD16+CD56+ are cytotoxic lymphoctyes also known as Natural Killer (NK) cells. NK lymphocytes destroy cells that are infected by viruses, cancer cells, or cells that are subject to rejection after tissue transplantation. CD3-CD16+CD56+ kill their target cells by secreting cytoplasmic proteins known as perforin and granzyme. Perforin perforate the target cell membrane to allow the granzyme to infiltrate the target cell which causes cell destruction by apoptosis or necrosis. The NK lymphocytes require activators and inhibitors to control their cytotoxic activity. Decreased levels of CD3-CD16+CD56+ lymphocytes make patients especially susceptible to the early phases of herpes infection. Information from Wikipedia and www.path.sunysb.edu, accessed 2008 09 05.
Source: Regenstrief Institute

Reference Information

Type Source Reference
Mapping Guidance Regenstrief Help NK cells - note that CD3- means they do not show CD3 markers. Mapper’s Guide for the Top 2000 plus LOINC Laboratory Observations

Fully-Specified Name

Component
Cells.CD3-CD16+CD56+/Cells
Property
NFr
Time
Pt
System
Bld
Scale
Qn
Method

Additional Names

Long Common Name
CD3-CD16+CD56+ (Natural killer) cells/cells in Blood
Short Name
CD3-CD16+CD56+ Cells NFr Bld
Display Name
CD3-CD16+CD56+ (Natural killer) cells/cells (Bld)
Consumer Name Alpha Get Info
CD3-CD16+CD56+ (Natural Killer) Cells/cells, Blood

Basic Attributes

Class
CELLMARK
Type
Laboratory
First Released
Version 1.0h(2)
Last Updated
Version 2.79 (NAM)
Change Reason
Release 2.79: COMPONENT: Triggered by Coll w SCT: This is a specific fraction case where the denominator is percentage or /100. Because the logic is that the percentage piece is captured by Property: NFr (Numeric Fraction), and by Unit: %, therefore, it is redundant to include "100" in the component;
Order vs. Observation
Observation
Common Test Rank Get Info
2098

Member of these Panels

LOINC Long Common Name
80721-4 Lymphocyte T-cell and B-cell and Natural killer subsets panel - Blood
98073-0 Natural killer and natural killer T cell subsets panel - Blood
53759-7 Natural killer cell panel - Blood by Flow cytometry (FC)

Language Variants Get Info

Tag Language Translation
de-AT German (Austria) Synonyms: NK-Zellen [Lympho]
de-DE German (Germany) Zellen.CD3-CD16+CD56+/Zellen:Anzahl pro Fraktion:Zeitpunkt:Blut:Quantitativ:
Synonyms: NK-Zellen
el-GR Greek (Greece) Κύτταρα.CD3-CD16+CD56+/κύτταρα:NFr:Pt:Αίμα:Qn:
Synonyms: CD16 CD3 CD56 NFr Κύτταρα Κύτταρα.CD3 Κύτταρα.CD3+CD16+ Κύτταρα.CD3+CD16+CD56+ Κύτταρα.CD3-CD16+ Κύτταρα.CD3-CD16+CD56+
es-AR Spanish (Argentina) células.células CD3-CD16+CD56+/100 células:fracción de un número:punto en el tiempo:sangre:cuantitativo:
es-ES Spanish (Spain) Células CD3-CD16+CD56+/células:Fracción numérica:Punto temporal:Sangre:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Células CD3-CD16 + CD56 + / 100 células:Fracción numérica:Punto temporal:Sangre:Cuantitativo:
fr-FR French (France) CD3-CD16+CD56+/100 cellules:Fraction de nombres:Ponctuel:Sang:Numérique:
fr-CA French (Canada) Cellules.CD3-CD16+CD56+/Cellules:Fraction numérique:Temps ponctuel:Sang:Quantitatif:
it-IT Italian (Italy) Cellule.CD3-CD16+CD56+/cellule:NFr:Pt:Sangue:Qn:
Synonyms: Cellule CD3 Cellule CD3+CD16+ Cellule CD3+CD16+CD56+ Cellule CD3-CD16+ Cellule CD3-CD16+CD56+ Frazione numerica Modelli di superficie cellulare Punto nel tempo (episodio) Sangue
ko-KR Korean (Korea, Republic Of) 세포.CD3-CD16+CD56+/100 세포:숫자분획:검사시점:전혈:정량:
nl-NL Dutch (Netherlands) cellen.CD3-CD16+CD56+/cellen:getalsfractie:moment:bloed:kwantitatief:
pt-BR Portuguese (Brazil) Células.CD3-CD16+CD56+/100 células:NFr:Pt:SgTotal:Qn:
Synonyms: ; CD3-CD16+CD56+ Cells; CD3-CD16+CD56+ Cells; CD3+CD16+CD56+ Cells; CD3-CD16+ Cells; CD3+CD16+ Cells; CD3 Cells; Cell; Cellularity; Leu19; Leu-19; NKH1; Neural cell adhesion molecule; NCAM; Leu-4; Leu4; T3; Leu-11; Leu11; Leu11b; Leu-11B; Gated cells; Fr; Number fraction; Percent; Point in time; Random; Blood; WB; Whole blood; Quantitative; QNT; Quant; Quan; CELL MARKERS
ru-RU Russian (Russian Federation) Клетки.CD3-CD16+CD56+/клетки:КолДоля:ТчкВрм:Кр:Колич:
Synonyms: CD3-CD16+CD56+ (естественные киллеры) клетки;NK Количественный Количество отношение Кровь Точка во времени;Момент
tr-TR Turkish (Turkey) Hücreler.CD3-CD16+CD56+/Hücreler:SayFr:Zmlı:Kan:Kant:
uk-UA Ukrainian (Ukraine) Клітини.CD3-CD16+CD56+/100 клітин:Чисельна Фракція:МоментЧасу:Кров:Кількісно:
Synonyms: Blood; CD3 Cells; CD3+CD16+ Cells; CD3+CD16+CD56+ Cells; CD3-CD16+ Cells; CD3-CD16+CD56+ Cells; Cell; CELL MARKERS; Cellularity; FCGR3A; Gated cells; Leu11; Leu-11; Leu11b; Leu-11B; Leu19; Leu-19; Leu4; Leu-4; Natural killer cells; NCAM; Neural cell adhesion molecule; NKH1; Number fraction; Percent; Point in time; QNT; Quan; Quant; Quantitative; Random; T3; WB; Whole blood
zh-CN Chinese (China) 细胞.CD3-CD16+CD56+/细胞:计数型分数:时间点:全血:定量型:
Synonyms: CD3+CD16+CD56+细胞 CD3+CD16+细胞 CD3-CD16+CD56+细胞 CD3-CD16+细胞 CD3细胞 Leu11;Leu-11;Leu11b;Leu-11B Leu19;Leu-19;NCAM;NKH1;神经细胞粘附分子;神经细胞粘附分子（Neural cell adhesion molecule，NCAM）;神经细胞黏附分子 Leu4;Leu-4;T3 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 数量型分数;数量或计数型分数;数量型分数或计数型分数 时刻;随机;随意;瞬间 细胞含量;细胞性;细胞性质;细胞构成;细胞类 细胞标志物 血;血液

Example Units

Unit Source
% Example UCUM Units
% REGENSTRIEF
% eCHN

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