Version 2.78

Part Description

LP28780-2   Islet cell 512
Islet cell antigen (ICA) 512 is a receptor-tyrosine phosphatase-like protein associated with the secretory granules of neuroendocrine cells. ICA-512 is also known as protein tyrosine phosphatase-IA2 (PTP-IA2) or tyrosine phosphatase (IA2). It is an autoantigen of type 1 diabetes. This is NOT the same as pancreatic islet cell. Studies on type-1 diabetic patient's relatives found that the development of one or more islet autoantibodies (including IA-2 antibody) was an early indicator of the relatives' progression to type-1 diabetes. Autoantibody profiles identifying patients destined to develop type-1 diabetes are usually detectable before age three. One study found that for relatives seropositive for IA-2 antibody, the likelihood of developing type-1 diabetes mellitus within five-years was 65.3%. Some type-1 diabetic patients are originally diagnosed as having type-2 diabetes due to symptom onset in adulthood, societal obesity, and initial insulin-independence. Detection of one or more islet auto-antibodies (including IA-2) may be used to distinguish these patients with "latent autoimmune diabetes" from type-2 diabetics. Source: Regenstrief Institute

Fully-Specified Name

Component
Islet cell 512 Ab
Property
SCnc
Time
Pt
System
Ser
Scale
Qn
Method

Additional Names

Short Name
Islet Cell512 Ab Ser-sCnc
Display Name
Islet cell 512 Ab (S) [Moles/Vol]
Consumer Name Alpha Get Info
Islet cell 512 antibody, Blood

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.56
Last Updated
Version 2.73
Order vs. Observation
Both
Common Test Rank Get Info
4373

Member of these Panels

LOINC Long Common Name
104673-9 Diabetes mellitus type 1 autoimmune panel - Serum or Plasma

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Célula de los islotes 512 Anticuerpos:Concentración de sustancia:Punto temporal:Suero:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Celda de islotes 512 Ab:Concentración de sustancias:Punto temporal:Suero:Cuantitativo:
fr-CA French (Canada) ICA 512 d'îlots de Langerhans, Ac:Concentration de substance:Temps ponctuel:Sérum:Quantitatif:
fr-FR French (France) Cellules îlots 512 anticorps:Moles/Volume:Ponctuel:Sérum:Numérique:
fr-BE French (Belgium) ICA 512 d'îlots de Langerhans Ac:Concentration de substance:Temps ponctuel:Sérum:Quantitatif:
Synonyms: Anticorps
it-IT Italian (Italy) Isola 512 cellula Ab:SCnc:Pt:Siero:Qn:
Synonyms: anticorpo Concentrazione di Sostanza Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant
nl-NL Dutch (Netherlands) islet antigeen-2 As:mol/volume:moment:serum:kwantitatief:
Synonyms: antistof; antilichaam IA-2
pl-PL Polish (Poland) Komórki wyspowe 512 Ab:stężenie molowe:punkt w czasie:surowica:ilościowy:
Synonyms: Antygen 512 komórek wyspowych
ru-RU Russian (Russian Federation) Островковая клетка 512 Ат:МолКонц:ТчкВрм:Сыв:Колич:
Synonyms: Антитело Количественный Молярность;Молярная объёмная концентрация Сыворотка Точка во времени;Момент
tr-TR Turkish (Turkey) Adacık hücresi 512 Ab:SubKons:Zmlı:Ser:Kant:
Synonyms: Ak
uk-UA Ukrainian (Ukraine) Острівцева клітина 512 Антитіла:Молярна Концентрація:МоментЧасу:Сироватка:Кількісно:
Synonyms: ABS; Aby; Antby; Anti; Antibodies; Antibody; Autoantibodies; Autoantibody; Endocrine; Endocrinology; IA2; IA-2; IA2-ab; ICA; ICA512; ICA-512; Islet Cell512; Level; Point in time; protein tyrosine phosphatase-like protein IA2; PtP-IA2; QNT; Quan; Quant; Quantitative; Random; Serology; Serum; SR; Substance concentration; Tyrosine phosphatase
zh-CN Chinese (China) 岛细胞 512 抗体:物质的量浓度:时间点:血清:定量型:
Synonyms: Ab;自身抗体 IA-2;ICA;ICA512;小岛细胞 512;小岛细胞 512（Islet cell 512）;岛细胞 512（Islet cell 512）;这里的岛细胞（ Islet Cell）并不等同于胰岛细胞（ Pancreatic Islet Cell） ICA ICA512 克分子浓度;克分子浓度(单位体积);摩尔浓度;摩尔浓度(单位体积);物质的量浓度(单位体积) 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 小岛细胞 512 Ab 小岛细胞 512 抗体 岛细胞 512 Ab 时刻;随机;随意;瞬间 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类

Example Units

Unit Source
nmol/L Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=81155-4