85832-4
Beta-lactam resistance ESBL blaCTX-M-1 Group gene [Presence] by Molecular method
Active
Term Description
This test reports the presence of the CTX-M1 group extended spectrum beta lactamase gene in gram negative bacterial isolates. This term was created for, but is not limited in use to, the submitter's modified protocol for the Check-Points Check-MDR CT103XL assay.
Source: Regenstrief LOINC
Part Description
LP248278-6 Bacterial beta-lactam resistance ESBL blaCTX-M-1 Group gene
Extended-spectrum beta-lactamases (ESBL) are enzymes produced by some bacteria that are resistant to the majority of beta-lactam antibiotics which include the penicillins, cephalosporins and the monobactam aztreonam. [https://www.uptodate.com/contents/extended-spectrum-beta-lactamases] Organisms producing CTX-M type ESBL enzymes have been isolated worldwide with more than 150 enzymes identified. These enzymes have been classified into seven major phylogenetic groups: CTX-M -1, CTX-M-2, CTX-M-8, CTX-M-9, CTX-M-25, CTX-M-74 and CTX-M-75. The rare ESBL type CTX-M-8 has been isolated in Germany, mainly in E. coli, but also in Salmonella and E. aerogenes. CTX-M type ESBL have been isolated worldwide and their incidence has increased dramatically and is still increasing leading to a major therapeutic issue. Currently more than 150 allelic variants of CTX-M have been identified. These enzymes are classified in five major phylogenetic groups based on their gene sequences: CTX-M -1, CTX-M-2, CTX-M-8, CTX-M-9, CTX-M-25; two additional groups have been reported recently: CTX-M-74 and CTX-M-75. The dissemination of these enzymes has caused an increased use of carbapenems for treatment of infections which carries its own risk of furthering resistance. PMID: 25234380 The genes are named with the prefix "bla", which stands for "beta-lactam", followed by the enzyme, for example, blaCTX-M-1.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Bacterial beta-lactam resistance ESBL blaCTX-M-1 group gene
- Property
- PrThr
- Time
- Pt
- System
- Isolate/Specimen
- Scale
- Ord
- Method
- Molgen
Additional Names
- Short Name
- ESBL blaCTX-M-1 Grp gene Islt/Spm Ql
- Display Name
- Beta-lactam resistance ESBL blaCTX-M-1 Group gene Molgen Ql (Islt/Spec)
- Consumer Name Alpha Get Info
- Beta-lactam Resistance ESBL blaCTX-M-1 Group gene
Example Answer List: LL360-9
Source: Regenstrief Institute| Answer | Code | Score | Answer ID |
|---|---|---|---|
| PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) | LA6576-8 | ||
| NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) | LA6577-6 |
Basic Attributes
- Class
- ABXBACT
- Type
- Laboratory
- First Released
- Version 2.61
- Last Updated
- Version 2.67
- Change Reason
- Updated System from "Isolate" and Method from "Probe.amp.tar" according to the new, more sustainable model for LOINC molecular resistance terms [Approved by LOINC Laboratory Committee in June 2018].
- Order vs. Observation
- Observation
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 93698-9 | Gram negative bacterial resistance panel by Molecular genetics method |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-DE | German (Germany) | Bakterielle Beta-Lactam-Resistenz ESBL blaCTX-M-1-Gruppe-Gen: Synonyms: Extended Spectrum beta-lactamases |
| es-ES | Spanish (Spain) | Grupo genes bacterianos ESBL blaCTX-M-1 resistentes a beta-lactámicos: |
| es-MX | Spanish (Mexico) | Resistencia bacteriana a betalactámicos BLEE gen del grupo blaCTX-M-1: |
| fr-FR | French (France) | Résistance bactérienne aux bêta lactamases ESBL blaCTX-M-1 groupe gène: |
| it-IT | Italian (Italy) | Resistenza batterica beta-lactamica, gene Gruppo ESBL blaCTX-M-1: Synonyms: Gene Gruppo ESBL blaCTX-M-1 di resistenza batterica beta-lactamica Genetica molecolare Isolato o Campione Presenza o Soglia Punto nel tempo (episodio) Suscettibilità agli antibiotici |
| nl-NL | Dutch (Netherlands) | bacteriële bètalactamresistentie ESBL blaCTX-M-1 groep gen: Synonyms: isolaat/specimen molgen |
| zh-CN | Chinese (China) | 细菌 beta-内酰胺耐药 ESBL blaCTX-M-1 组基因: Synonyms: Ⅰ B I M 型 β 供检查用的材料; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=85832-4
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LOINC Copyright
Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright