Version 2.78

Term Description

This term is used to report the presence or absence of IgG antibodies against Porcine epidemic virus (PEDv) based on an immunofluorescence staining pattern. IgG antibodies to PEDv are typically be detected 7 to 14 days following exposure. Samples are compared to positive and negative controls. If cells fluoresce brilliant blue-green color against a background of non-infected cells, then the sample is considered positive; If cells do not fluoresce brilliantly but may show background non-specific fluorescence, then the sample is considered negative.; If cells fluoresce weakly and is not background fluorescence, then the sample is considered suspect. If high background fluorescence does not allow for an accurate determination to be made, then the sample is considered inconclusive.
Source: Regenstrief LOINC

Part Description

LP182479-8   Porcine epidemic diarrhea virus
Porcine Epidemic Diarrhea Virus (PEDv) is a large-enveloped RNA virus, which is a member of the genus Alphacoronavirus within the Coronaviridae family. The complete PEDv genome consists of 5 gene segments: open reading frame 1 (ORF1), spike (S), envelope (E), membrane (M), and nucleocapsid (N). It is encapsulated by a single N protein. The S protein contributes to the stimulation of neutralizing antibodies in the infected host. Its association to adapted growth in vitro and attenuation in vivo lends itself to use for genetic comparison among PEDV isolates and effective vaccines. The M protein is required for assembly and can also induce the production of virus-neutralizing antibodies. The E protein contributes to coronavirus budding. The N protein has functions associated with viral replication and pathogenesis.
PEDv causes viral enteritis, which leads to the destruction of villus enterocytes in pigs of all ages. It is spread by the ingestion of feces from infected pigs, resulting in vomiting, watery diarrhea, dehydration, and high mortality, especially in nursery piglets. Disease caused by PEDv is clinically similar to that caused by Transmissible gastroenteritis coronavirus (TGEV) PMID: 26689811
At least two PEDv strains have been identified in the USA: the US PEDv prototype and S INDEL variant. The INDEL variant PEDv strain has insertions and deletions (INDELs) in the spike (S) gene. PMID: 25279722 The INDEL strain is related to milder clinical signs than prototype strains. PMID: 24750580 PMID: 26748596 The genomic differences in the S gene between the US PEDv prototype and INDEL variant may be responsible for the virulence differences. Potential targets when testing for PEDv RNA include the nucleocapsid protein (N) gene and the ~2500 bp fragment of the S-gene. Source: Regenstrief LOINC

Fully-Specified Name

Component
Porcine epidemic diarrhea virus Ab.IgG
Property
PrThr
Time
Pt
System
Ser
Scale
Ord
Method
IF

Additional Names

Short Name
PEDv IgG Ser Ql IF
Display Name
Porcine epidemic diarrhea virus IgG IF Ql (S)
Consumer Name Alpha Get Info
Porcine Epidemic Diarrhea virus IgG antibody, Blood

Example Answer List: LL2431-6

Source: Regenstrief LOINC
Answer Code Score Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6
InconclusiveCopyright http://snomed.info/sct ID:419984006 Inconclusive (qualifier value) LA9663-1

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.61
Last Updated
Version 2.61
Order vs. Observation
Observation

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Virus de la diarrea epidémica porcina IgG:PrThr:Punto temporal:Suero:Ord:Inmunofluorescencia (IF)
es-MX Spanish (Mexico) Virus de la diarrea epidémica porcina Ab.IgG:Presencia o umbral:Punto temporal:Suero:Ordinal:Inmunofluorescencia (IF)
it-IT Italian (Italy) Virus della diarrea epidemica suina Ab.IgG:PrThr:Pt:Siero:Ord:IF
Synonyms: anticorpi IgG anticorpo Immunofluorescenza (IF) Microbiologia Presenza o Soglia Punto nel tempo (episodio) Siero Virus PED
nl-NL Dutch (Netherlands) 'porcine' epizoötisch diarreevirus As.IgG:aanwezigheid:moment:serum:ordinaal:immunofluorescentie
Synonyms: antistof; antilichaam epizoötisch diarreevirus van varken IF porcine
pl-PL Polish (Poland) Wirus epidemicznej biegunki świń Ab.IgG:granica wykrywalności:punkt w czasie:surowica:półilościowy:immunofluorescencja
Synonyms: IgG
ru-RU Russian (Russian Federation) Свиная эпидемическая диаррея вирус Ат.IgG:PrThr:ТчкВрм:Сыв:Пор:ИФ
Synonyms: Антитело Иммунофлюоресценция (ИФ) Порядковый Сыворотка Точка во времени;Момент
tr-TR Turkish (Turkey) Porsin epidemik diyare virüsü Ab.IgG:MevcEşik:Zmlı:Ser:Srl:IF
Synonyms: Ak Ak.IgG İmmünflorerans Mevcut
zh-CN Chinese (China) 猪流行性腹泻病毒 抗体.IgG:存在情况或阈值:时间点:血清:序数型:免疫荧光法
Synonyms: Ab.IgG;IgG;抗体 IgG Ab;自身抗体 IFA法;IF法;抗补体免疫荧光法;时间分辨荧光法;荧光原位杂交技术;荧光原位杂交法;荧光抗体 下痢;泄泻;下利;泻肚 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 免疫球蛋白 G 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 时刻;随机;随意;瞬间 猪传染性腹泻病毒;PEDv 猪的 猪科 猪科的

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CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=86207-8