Version 2.78

Term Description

The pattern of reactive bands specific to IgM antibodies associated with Borrelia afzelii, B burgdorferi, and B garinii species in human serum. Antibodies against p39, OspC, Osp17 and VlsE antigens are characterized as highly specific for Borrelia species, whereas p41 shows only limited specificity. The presence of specific bands suggests a recent infection of Lyme disease. This term was created for, but not limited in use to, the Borrelia ViraStripe IgM assay, which uses native, purified antigens immobilized on a test strip to which patient antibodies, if present, will bind. Various manufacturers label this method as an immunoblot technique. LOINC uses the immunoblot (IB) method to mean that some electrophoretic/chromatographic separation occurs such that position (size) of the band is part of the laboratory assessment (as in Western blot). Because this assay does not involve a separation step but rather uses strips with pre-fixed antigens, the LOINC Method is Line blot.
Source: Regenstrief LOINC

Part Description

LP262543-4   Borrelia afzelii+burgdorferi+garinii
Borrelia afzelii, B borgdorferi, and B garinii are spirochetes and known etiological agents of Lyme borreliosis (Lyme disease). B garinii and B afzelii are more prevalent in Europe and regions of Asia, whereas B borgdorferi is the primary agent causing in Lyme disease in North America. PMID: 21414082 Travelers or residents of these regions who are bitten by ticks are at increased risk for Lyme disease caused by a Borrelia species. The bacteria are transmitted to humans by the bite of infected ticks of the Ixodes genus. PMID: 21413339 Many patients will develop a red rash (erythema migrans) at the site of the tick bite. Other symptoms include fever, headache, feeling tired, facial nerve paralysis, joint pains, and meningitis. Symptoms can occur within a few days to a month or more after the bite. Antibiotics commonly used for oral treatment of Lyme disease include doxycycline, amoxicillin, or cefuroxime axetil.[CDC:lyme] Source: Regenstrief LOINC

Fully-Specified Name

Component
Borrelia afzelii+burgdorferi+garinii Ab.IgM band pattern
Property
Imp
Time
Pt
System
Ser
Scale
Nom
Method
Line blot

Additional Names

Short Name
B afz+burg+gari IgM Ptrn Ser Line blot
Display Name
B. afzelii+burgdorferi+garinii IgM band pattern Line blot (S) [Interp]
Consumer Name Alpha Get Info
Borrelia afzelii+burgdorferi+garinii IgM band pattern, Blood

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.63
Last Updated
Version 2.67
Change Reason
This term was created for an assay that uses a membrane strip pre-coated with a specific set of antigens in parallel lines. Because the antigens are seperated by electrophoresis/chromatographic separation during manufacturing, not during the test procedure itself, this test was assigned a LOINC Method of Immunoassay (IA) and not Immunoblot (IB). However, upon further review of IA, IB, and Immunoblot strip methodologies and regulatory distinctions between these, we changed the Method from IA to Line blot so that users can distinguish between these three Methods. The meaning of the term has not changed since it was created for an IB strip assay as described in the term description.
Order vs. Observation
Observation

Member of these Panels

LOINC Long Common Name
87274-7 Borrelia afzelii+burgdorferi+garinii IgG and IgM panel - Serum by Line blot

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Borrelia afzelii+burgdorferi+garinii Patrón de bandas de Ac. Ig M:Impresión/interpretación del estudio:Punto temporal:Suero:Nom:Line blot
es-MX Spanish (Mexico) Borrelia afzelii + burgdorferi + garinii Ab.IgM patrón de bandas:Impresión / interpretación del estudio:Punto temporal:Suero:Nominal:Mancha de línea
fr-FR French (France) Borrelia afzelii+burgdorferi+garinii Ac IgM bandes:Interprétation:Ponctuel:Sérum:Résultat nominal:Blot en ligne
it-IT Italian (Italy) Borrelia afzelii+burgdorferi+garinii Ab.profilo di banda IgM:Imp:Pt:Siero:Nom:Line blot
Synonyms: Anticorpi IgM anticorpo Impressione/interpretazione di studio Microbiologia Profilo di banda delle IgM Punto nel tempo (episodio) Siero
nl-NL Dutch (Netherlands) Borrelia afzelii + burgdorferi + garinii As.IgM-bandenpatroon:interpretatie:moment:serum:nominaal:lijnblot
Synonyms: antistof; antilichaam borrelia afzelii
zh-CN Chinese (China) 阿夫塞疏螺旋体+伯氏疏螺旋体+加里疏螺旋体 抗体.IgM 区带模式:印象:时间点:血清:名义型:线点印迹法
Synonyms: Ab.IgM;IgM;抗体 IgM Ab;自身抗体 Afzelii 疏螺旋体;Afzelii 螺旋体;阿氏疏螺旋体;阿夫塞疏螺旋体;Afzelii 包柔氏螺旋体;B Afzelii;Borrelia afzelii 免疫球蛋白 M 分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答 区带 区带（带型、条带）模式（模式特征、特征模式、图谱、式样、组份、组分、成员） 印象是一种诊断陈述，始终是对其他某种观察指标的解释或抽象（一系列检验项目结果、一幅图像或者整个某位病人），而且几乎总是由某位专业人员产生。;检查印象;检查印象/解释;检查的印象/解释;检查解释;解释;阐释 带 带状 带状核 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 抗体.IgM 带型;抗体.IgM 条带模式;Ab.IgM 区带模式;Ab.IgM 带型;Ab.IgM 条带模式（模式特征、特征模式、图谱、式样、组份、组分、成员） 时刻;随机;随意;瞬间 杆 杆状核 线点杂交技术;线点杂交法;线条状印迹法 阿夫塞疏螺旋体（Afzelii 疏螺旋体、Afzelii 螺旋体、阿氏疏螺旋体、阿夫塞疏螺旋体、Afzelii 包柔氏螺旋体、B Afzelii）+伯氏疏螺旋体（伯氏包柔螺旋体、伯氏包柔氏螺旋体）+加里疏螺旋体（加里螺旋体菌、伽里疏螺旋体、加林螺旋体菌、伽里尼疏螺旋体、伽氏疏螺旋体、Garinii 疏螺旋体）

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